Molecular characterization of the HLA-linked steroid 21-hydroxylase B gene from an individual with congenital adrenal hyperplasia.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

HISTOCOMPATIBILITY TESTING, 1972

1974 • 1,267 citations

Oxygen Activation by Cytochrome P-4501

1980 • 1,013 citations

Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

1981 • 910 citations

Structure of human steroid 21-hydroxylase genes.

1986 • 568 citations

Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene.

1986 • 559 citations

Photochemical Action Spectrum of the Terminal Oxidase of Mixed Function Oxidase Systems

1965 • 503 citations

Two genes encoding steroid 21-hydroxylase are located near the genes encoding the fourth component of complement in man.

1985 • 492 citations

A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B

1984 • 433 citations

The structural basis of the multiple forms of human complement component C4

1984 • 419 citations

CLOSE GENETIC LINKAGE BETWEEN HLA AND CONGENITAL ADRENAL HYPERPLASIA (21-HYDROXYLASE DEFICIENCY)

1977 • 372 citations

Mapping of steroid 21-hydroxylase genes adjacent to complement component C4 genes in HLA, the major histocompatibility complex in man.

1985 • 371 citations

The gene structure of human anti-haemophilic factor IX.

1984 • 361 citations

HLA-linked congenital adrenal hyperplasia results from a defective gene encoding a cytochrome P-450 specific for steroid 21-hydroxylation.

1984 • 291 citations

Statement on the Nomenclature of Human C4 Allotypes

1983 • 228 citations

Structural basis of the polymorphism of human complement components C4A and C4B: gene size, reactivity and antigenicity.

1986 • 220 citations

Deletion of complement C4 and steroid 21-hydroxylase genes in the HLA class III region.

1985 • 209 citations

Molecular cloning and nucleotide sequence of cDNA for mRNA of mitochondrial cytochrome P-450(SCC) of bovine adrenal cortex.

1984 • 208 citations

Polymorphism of human complement component C4

1985 • 136 citations

Gene Conversion in Salt-Losing Congenital Adrenal Hyperplasia with Absent Complement C4B Protein*

1986 • 127 citations

Cloning and expression of cDNA encoding a bovine adrenal cytochrome P-450 specific for steroid 21-hydroxylation.

1984 • 105 citations

Nucleotide sequence analysis of murine 21-hydroxylase genes: mutations affecting gene expression.

1986 • 102 citations

Structure of a bovine gene for P-450c21 (steroid 21-hydroxylase) defines a novel cytochrome P-450 gene family.

1986 • 96 citations

Structure and organization of theC4genes

1984 • 89 citations

Inborn errors of steroid biosynthesis.

1979 • 88 citations

Structural analysis of cloned cDNA for mRNA of microsomal cytochrome P-450(C21) which catalyzes steroid 21-hydroxylation in bovine adrenal cortex.

1986 • 70 citations

Models for ferric cytochrome P450. Characterization of hemin mercaptide complexes by electronic and ESR spectra

1979 • 68 citations

Deletion of the steroid 21-hydroxylase and complement C4 genes in congenital adrenal hyperplasia.

1986 • 64 citations

Steroid 21-hydroxylase (cytochrome P-450) from porcine adrenocortical microsomes: microsequence analysis of cysteine-containing peptides

1983 • 59 citations

Rodgers (Rg) and Chido (Ch) determinants on human C4: characterization of two C4 B5 subtypes, one of which contains Rg and Ch determinants.

1984 • 58 citations

Endogenous cysteine ligation in ferric and ferrous cytochrome P-450. Direct evidence from x-ray absorption spectroscopy.

1982 • 49 citations

Recent Advances in 21-Hydroxylase Deficiency

1984 • 43 citations

C4 AND HLA HAPLOTYPES ASSOCIATED WITH PARTIAL INHIBITION OF ANTI‐RG AND ANTI‐CH

1984 • 34 citations

Some guidelines for identification of recognition sequences: Regulatory sequences frequently contain (T)GTG/CAC(A), TGA/TCA and (T)CTC/GAG(A)

1986 • 19 citations

Model systems for the coordination chemistry of cytochrome P-450.

1979 • 1 citations