Vasopressin induces V1 receptors to activate phosphatidylinositol- and phosphatidylcholine-specific phospholipase C and stimulates the release of arachidonic acid by at least two pathways in the smooth muscle cell line, A-10.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

Production of diglyceride from phosphatidylinositol in activated human platelets.

1979 • 727 citations

Diglyceride lipase: a pathway for arachidonate release from human platelets.

1979 • 696 citations

Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of the toxin-specific substrate in the Ca2+-mobilizing receptor-mediated biosignaling system.

1985 • 509 citations

Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells.

1986 • 491 citations

Effect of vasopressin and cyclic AMP on permeability of isolated collecting tubules

1966 • 448 citations

Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin

1984 • 418 citations

Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger.

1986 • 415 citations

Identification of neutral active phospholipase C which hydrolyzes choline glycerophospholipids and plasmalogen selective phospholipase A2 in canine myocardium.

1985 • 315 citations

Stimulation of 1,2-diacylglycerol accumulation in hepatocytes by vasopressin, epinephrine, and angiotensin II.

1985 • 304 citations

Phospholipase A2 and phospholipase C activities of platelets. Differential substrate specificity, Ca2+ requirement, pH dependence, and cellular localization.

1980 • 287 citations

Pertussis toxin does not inhibit muscarinic-receptor-mediated phosphoinositide hydrolysis or calcium mobilization

1985 • 284 citations

A novel mechanism of diglyceride formation. 12-O-tetradecanoylphorbol-13-acetate stimulates the cyclic breakdown and resynthesis of phosphatidylcholine.

1986 • 267 citations

Regulation of prostaglandin synthesis and of the selective release of lysosomal hydrolases by mouse peritoneal macrophages

1978 • 255 citations

Phosphatidylcholine breakdown in rat liver plasma membranes. Roles of guanine nucleotides and P2-purinergic agonists.

1987 • 253 citations

Regulation of arachidonic acid production: role of phospholipases C and A2

1982 • 239 citations

Prostaglandin synthesis by rat glomerular mesangial cells in culture. Effects of angiotensin II and arginine vasopressin.

1983 • 228 citations

Advances in Inflammation Research

1983 • 211 citations

Phosphatidic and lysophosphatidic acid production in phospholipase C-and thrombin-treated platelets. possible involvement of a platelet lipase

1978 • 166 citations

Prostaglandin E2 biosynthesis by rabbit renomedullary interstitial cells in tissue culture. Mechanism of stimulation by angiotensin II, bradykinin, and arginine vasopressin.

1977 • 163 citations

Diacylglycerol accumulation and superoxide anion production in stimulated human neutrophils.

1987 • 103 citations

The effect of arginine vasopressin and its analogs on the synthesis of prostaglandin E2 by rat renal medullary interstitial cells in culture.

1980 • 102 citations

Antibodies prepared to Bacillus cereus phospholipase C crossreact with a phosphatidylcholine preferring phosoholipase C in mammalian cells

1986 • 97 citations

Activation of V1-receptors by vasopressin stimulates inositol phospholipid hydrolysis and arachidonate metabolism in human platelets

1986 • 97 citations

Activation of phospholipase C and prostaglandin synthesis by [arginine]vasopressin in cultures

1984 • 94 citations

Vasopressin induced production of inositol trisphosphate and calcium efflux in a smooth muscle cell line

1985 • 91 citations

Leukotriene D4 treatment of bovine aortic endothelial cells and murine smooth muscle cells in culture results in an increase in phospholipase A2 activity.

1986 • 90 citations

Evidence for sequential signals in the induction of the arachidonic acid cascade in macrophages.

1986 • 80 citations

Prostaglandin production by homogeneous cultures of rat glomerular epithelial and mesangial cells

1982 • 68 citations

Vascular vasopressin receptors mediate phosphatidylinositol turnover and calcium efflux in an established smooth muscle cell line

1986 • 67 citations

Phosphatidylcholine metabolism in endothelial cells: Evidence for phospholipase A and a novel Ca2+-independent phospholipase C

1987 • 58 citations

A transient increase in diacylglycerols is associated with the action of vasopressin on hepatocytes

1984 • 53 citations

Vasoconstrictor-evoked prostaglandin synthesis in cultured vascular smooth muscle

1983 • 48 citations

Mechanism of action of vasopressin on prostaglandin synthesis and vascular function in the isolated rat kidney: effect of calcium antagonists and calmodulin inhibitors.

1984 • 33 citations

A selective defect in arachidonic acid release from macrophage membranes in high potassium media.

1984 • 32 citations

Identification and characterization of vascular (V1) vasopressin receptors of an established smooth muscle cell line.

1987 • 25 citations