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2‘,5‘-Oligoadenylate-dependent RNase L is a dimer of regulatory and catalytic subunits.

Data up to Jan 2025

Published1993
Citations31
References26

Total Citations Per Year

Abstract

References (26)

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

1977 • 3,556 citations

pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells.

1978 • 787 citations

An absolute method for protein determination based on difference in absorbance at 235 and 280 nm

1980 • 592 citations

Interferon Action: RNA Cleavage Pattern of a (2′-5′)Oligoadenylate—Dependent Endonuclease

1981 • 357 citations

Constitutive expression of (2′–5′) oligo A synthetase confers resistance to picornavirus infection

1987 • 277 citations

Ribosomal RNA cleavage, nuclease activation and 2-5A (ppp(A2′p)nA) in interferon-treated cells

1981 • 245 citations

Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells

1980 • 242 citations

Interferon, double-stranded RNA, and RNA degradation: activation of an endonuclease by (2'-5')An.

1979 • 140 citations

New monoclonal antibodies directed against human renin. Powerful tools for the investigation of the renin system.

1984 • 133 citations

Constitutive Expression of a 2′,5′-Oligoadenylate Synthetase cDNA Results in Increased Antiviral Activity and Growth Suppression

1989 • 133 citations

Interaction of cAMP Derivatives with the ‘Stable’ CAMP‐Binding Site in the CAMP‐Dependent Protein Kinase Type I

1982 • 111 citations

A full-length murine 2-5A synthetase cDNA transfected in NIH-3T3 cells impairs EMCV but not VSV replication

1990 • 96 citations

Purification and analysis of murine 2-5A-dependent RNase.

1988 • 83 citations

Nuclease activity associated with mammalian mRNA in its native state: possible basis for selectivity in mRNA decay.

1990 • 81 citations

Synthesis, Characterization and Properties of ppp(A2′p)nApCp and Related High-Specific-Activity 32P-Labelled Derivatives of ppp(A2′p)nA

2005 • 79 citations

Affinity Labelling and Characterization of the ppp(A2′p)nA‐Dependent Endoribonuclease from Different Mammalian Sources

1982 • 78 citations

Continuous Production of Interferon in Normal Mice: Effect of Anti-interferon Globulin, Sex, Age, Strain and Environment on the Levels of 2-5A Synthetase and p67K Kinase

1985 • 72 citations

Functional analysis of 2-5A-dependent RNase and 2-5A using 2′,5′-oligoadenylate-cellulose

1985 • 64 citations

Interferon action. Covalent linkage of (2'-5')pppApApA(32P)pCp to (2'-5')(A)n-dependent ribonucleases in cell extracts by ultraviolet irradiation.

1982 • 53 citations

Activation of ribonuclease L by (2'-5')(A)4-poly(L)-lysine) conjugates in intact cells

1986 • 50 citations

Production and Characterization of Monoclonal Antibodies Against Human Thyroglobulin

1985 • 50 citations

Characterization of two murine (2′‐5′)(A)n‐dependent endonucleases of different molecular mass

1989 • 46 citations

Phosphorothioate analogs of (2'-5')(A)4: agonist and antagonist activities in intact cells

1990 • 28 citations

Polyclonal antibodies against RNase L. Subcellular localization of this enzyme in mouse cells.

1991 • 20 citations

Regeneration of enzyme activity after Western blot: Activation of RNase L by 2-5A on filter— Importance for its detection

1991 • 7 citations

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2‘,5‘-Oligoadenylate-dependent RNase L is a dimer of regulatory and catalytic subunits. (1993) – Journal of Biological Chemistry | Metascience Observatory Explorer