Phosphorothioate analogs of (2'-5')(A)4: agonist and antagonist activities in intact cells

Biochemistry of Interferons and Their Actions

1982 • 868 citations

Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity

1988 • 278 citations

Automated solid-phase synthesis, separation, and stereochemistry of phosphorothioate analogs of oligodeoxyribonucleotides

1984 • 272 citations

Ribosomal RNA cleavage, nuclease activation and 2-5A (ppp(A2′p)_nA) in interferon-treated cells

1981 • 245 citations

Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells

1980 • 242 citations

Synthesis of 2'5'-oligo(A) in extracts of interferon-treated HeLa cells.

1979 • 174 citations

Phosphorothioates in molecular biology

1989 • 173 citations

[30] Microinjection of tissue culture cells

1983 • 160 citations

Purification and analysis of murine 2-5A-dependent RNase.

1988 • 83 citations

Synthesis, Characterization and Properties of ppp(A2′p)nApCp and Related High-Specific-Activity 32P-Labelled Derivatives of ppp(A2′p)nA

2005 • 79 citations

Affinity Labelling and Characterization of the ppp(A2′p)_nA‐Dependent Endoribonuclease from Different Mammalian Sources

1982 • 78 citations

Expression of the 2-5A system druing the cell cycle

1985 • 77 citations

Chemical modification potentiates the biological activities of 2-5A and its congeners.

1982 • 65 citations

Functional analysis of 2-5A-dependent RNase and 2-5A using 2′,5′-oligoadenylate-cellulose

1985 • 64 citations

Phosphorothioate analogs of 2',5'-oligoadenylate. Enzymatically synthesized 2',5'-phosphorothioate dimer and trimer: unequivocal structural assignment and activation of 2',5'-oligoadenylate-dependent endoribonuclease

1987 • 57 citations

Activation of ribonuclease L by (2'-5')(A)4-poly(L)-lysine) conjugates in intact cells

1986 • 50 citations

[13] Stereochemistry of enzymic phosphoryl and nucleotidyl transfer

1982 • 49 citations

Microinjection of Interferon and 2′,5′-Oligoadenylate into Mouse L Cells and Their Effects on Virus Growth

1982 • 47 citations

Characterization of two murine (2′‐5′)(A)_n‐dependent endonucleases of different molecular mass

1989 • 46 citations

Increased stability and antiviral activity of 2′‐O‐phosphoglyceryl derivatives of (2′‐5′)oligo(adenylate)

1984 • 44 citations

Phosphorothioate analogs of 2',5'-oligoadenylate. Activation of 2',5'-oligoadenylate-dependent endoribonuclease by 2',5'-phosphorothioate cores and 5'-monophosphates

1987 • 44 citations

[27] Analysis of (2′-5′)-oligo(A) and related oligonucleotides by high-performance liquid chromatography

1981 • 33 citations

5'-Modified agonist and antagonist (2'-5')(A)n analogs: synthesis and biological activity

1987 • 28 citations

Phosphorothioate analogs of 2',5'-oligoadenylate. Enzymic synthesis, properties, and biological activities of 2',5'-phosphorothioates from adenosine 5'-O-(2-thiotriphosphate) and adenosine 5'-O-(3-thiotriphosphate)

1987 • 25 citations

Antiviral activity of a chemically stabilized 2‐5A analog upon microinjection into HeLa cells

1986 • 13 citations

Phosphorothioate Analogs OF 2-5A: Activation / Inhibition of Rnase L and Inhibition of HIV-1 Reverse Transcriftase

1989 • 13 citations

An Antiviral State Induced in HeLa Cells by Microinjected Poly(rI){middle dot}Poly(rC)

1986 • 12 citations

Synthesis, Specific Intracellular Delivery and Biological Activity of Novel Stabilized (2′-5′)(A)_nAnalogues

1985 • 6 citations