Auranofin modulated cytoplasmic free calcium in neutrophils by mobilizing intracellular calcium and inhibiting protein kinase.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

A model for receptor-regulated calcium entry

1986 • 2,535 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Use of Manganese to Discriminate Between Calcium Influx and Mobilization From Internal Stores in Stimulated Human Neutrophils

1989 • 520 citations

Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration

1986 • 489 citations

"Calciosome," a cytoplasmic organelle: the inositol 1,4,5-trisphosphate-sensitive Ca2+ store of nonmuscle cells?

1988 • 451 citations

Ca2+ homeostasis in permeabilized human neutrophils. Characterization of Ca2+-sequestering pools and the action of inositol 1,4,5-triphosphate.

1984 • 266 citations

Choline-linked Phosphoglycerides

1989 • 234 citations

Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils.

1985 • 196 citations

Phorbol myristate acetate stimulates ATP-dependent calcium transport by the plasma membrane of neutrophils.

1984 • 193 citations

Nucleotide regulatory protein-mediated activation of phospholipase C in human polymorphonuclear leukocytes is disrupted by phorbol esters.

1987 • 184 citations

Inositol(1,3,4,5)tetrakisphosphate-induced activation of sea urchin eggs requires the presence of inositol trisphosphate

1987 • 163 citations

Characterization of fMet-Leu-Phe receptor-mediated Ca2+ influx across the plasma membrane of human neutrophils.

1986 • 157 citations

Activation of the human neutrophil by calcium-mobilizing ligands. II. Correlation of calcium, diacyl glycerol, and phosphatidic acid generation with superoxide anion generation.

1988 • 133 citations

Calcium influx stimulates a second pathway for sustained diacylglycerol production in leukocytes activated by chemoattractants.

1988 • 119 citations

Phorbol myristate acetate (PMA) augments chemoattractant-induced diglyceride generation in human neutrophils but inhibits phosphoinositide hydrolysis. Implications for the mechanism of PMA priming of the respiratory burst.

1988 • 101 citations

Cellular association, intracellular distribution, and efflux of auranofin via sequential ligand exchange reactions

1986 • 95 citations

Quantitative changes in inositol 1,4,5-trisphosphate in chemoattractant-stimulated neutrophils.

1986 • 88 citations

Chemoattractant receptor promotion of Ca2+ influx across the plasma membrane of HL-60 cells

1989 • 77 citations

Evidence that phorbol ester interferes with stimulated Ca2+ redistribution by activating Ca2+ efflux in neutrophil leucocytes

1985 • 76 citations

Phorbol 12, myristate 13, acetate potentiates the respiratory burst while inhibits phosphoinositide hydrolysis and calcium mobilization by formyl-methionyl-leucyl-phenylalanine in human neutrophils

1986 • 73 citations

Changes in diacylglycerol labeling, cell shape, and protein phosphorylation distinguish “triggering” from “activation” of human neutrophils.

1988 • 72 citations

Use of fluoride ion as a probe for the guanine nucleotide‐binding protein involved in the phosphoinositide‐dependent neutrophil transduction pathway

1986 • 72 citations

Effects of sulfhydryl reagents and other inhibitors on Ca2+ transport and inositol trisphosphate-induced Ca2+ release from human platelet membranes.

1986 • 72 citations

Signal transduction in cells following binding of chemoattractants to membrane receptors

1988 • 62 citations

Phorbol ester stimulates calcium sequestration in saponized human platelets.

1987 • 59 citations

Propionic acid‐induced calcium mobilization in human neutrophils

1988 • 55 citations

Are Ca²⁺ channels in neutrophils activated by a rise in cytosolic free Ca²⁺?

1987 • 54 citations

Cellular and molecular pharmacology of auranofin and related gold complexes

1986 • 46 citations

Diacylglycerols Modulate Human Polymorphonuclear Neutrophil Responsiveness: Effects on Intracellular Calcium Mobilization, Granule Exocytosis, and Superoxide Anion Production

1988 • 33 citations

N-formylpeptide-receptor dynamics, cytoskeletal activation, and intracellular calcium response in human neutrophil cytoplasts.

1987 • 32 citations

Effects of gold coordination complexes on neutrophil function are mediated via inhibition of protein kinase C.

1989 • 29 citations

Cellular interactions of auranofin and a related gold complex with raw 264.7 macrophages

1987 • 28 citations

Lysosomotropic amines modulate neutrophil calcium homeostasis

1988 • 20 citations

[10] Preparation and cryopreservation of cytoplasts from human phagocytes

1986 • 11 citations

Calcium release associated with discharge of specific granule contents from human neutrophils

1988 • 6 citations

Separation and function of neutrophil karyogranuloplasts and comparison with cytoplasts and intact cells

1987 • 2 citations