Binding of G protein beta gamma-subunits to pleckstrin homology domains.

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

1991 • 1,590 citations

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

1993 • 1,438 citations

Identification of a Ten-Amino Acid Proline-Rich SH3 Binding Site

1993 • 1,205 citations

A Divergence in the MAP Kinase Regulatory Network Defined by MEK Kinase and Raf

1993 • 1,086 citations

SH2 and SH3 domains: From structure to function

1992 • 977 citations

Solubilization and Purification of Enzymatically Active Glutathione S-Transferase (pGEX) Fusion Proteins

1993 • 891 citations

Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors

1992 • 703 citations

Cloning of bovine GAP and its interaction with oncogenic ras p21

1988 • 666 citations

New roles for G-protein (βγ-dimers in transmembrane signalling

1993 • 633 citations

The PH domain: a common piece in the structural pathcwork of signalling proteins

1993 • 536 citations

Structure and mechanism of the G protein-coupled receptor kinases.

1993 • 480 citations

The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase.

1993 • 467 citations

β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family

1989 • 451 citations

Receptor-to-effector signaling through G proteins: Roles for βγ dimers as well as α subunits

1992 • 441 citations

Light-dependent phosphorylation of rhodopsin: number of phosphorylation sites

1982 • 441 citations

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

1992 • 361 citations

Signalling through SH2 and SH3 domains

1993 • 355 citations

Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases

1992 • 306 citations

Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase.

1993 • 241 citations

Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts.

1993 • 234 citations

Inositol phospholipid-specific phospholipase C: complete cDNA and protein sequences and sequence homology to tyrosine kinase-related oncogene products.

1988 • 223 citations

Molecular cloning of a second form of rac protein kinase.

1991 • 182 citations

Interaction between G-protein beta and gamma subunit types is selective.

1992 • 157 citations

G protein .beta..gamma. subunits from bovine brain and retina: equivalent catalytic support of ADP-ribosylation of .alpha. subunits by pertussis toxin but differential interactions with Gs.alpha.

1989 • 139 citations

Beta spectrin in human skeletal muscle. Tissue-specific differential processing of 3' beta spectrin pre-mRNA generates a beta spectrin isoform with a unique carboxyl terminus

1990 • 110 citations

Identification of Novel Pleckstrin Homology (PH) Domains Provides a Hypothesis for PH Domain Function

1993 • 99 citations

cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19

1990 • 81 citations

Do G protein subunits associate via a three‐stranded coiled coil?

1992 • 59 citations

New insights into protein‐tyrosine kinase receptor signaling complexes

1993 • 58 citations

G proteins and βARK: a new twist for the coiled coil

1993 • 35 citations

Sequence similarity of phospholipase A2 activating protein and the G protein β-subunits: a new concept of effector protein activation in signal transduction?

1993 • 32 citations