Lipid Metabolism in the Fetal-Placental Unit

Body composition of the reference fetus.

1976 • 713 citations

A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis.

1977 • 705 citations

Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA.

1978 • 586 citations

Factors Influencing the Rates of Long-Chain Fatty Acid Oxidation and Synthesis in Mammalian Systems

1961 • 479 citations

Studies on the mechanism of fatty acid synthesis

1960 • 408 citations

Fuels, Hormones, and Liver Metabolism at Term and during the Early Postnatal Period in the Rat

1973 • 351 citations

Chemical Composition of Newly Born Mammals

1950 • 306 citations

The role of malonyl-coa in the coordination of fatty acid synthesis and oxidation in isolated rat hepatocytes.

1978 • 269 citations

Role of carnitine in hepatic ketogenesis.

1975 • 266 citations

Changes in lipid synthesis in rat liver during development

1967 • 230 citations

Studies on the inhibition of hepatic lipogenesis by N6,O2′-dibutyryl adenosine 3′,5′-monophosphate

1975 • 196 citations

Lipoprotein Metabolism in Pregnancy, Fat Transport to the Fetus, and the Effects of Diabetes

1986 • 191 citations

Ketone Bodies as Precursors of Sterols and Fatty Acids in the Developing Rat

1974 • 175 citations

Changes in hepatic lipogenesis during development of the rat

1967 • 171 citations

Two Phases of Adipose Tissue Metabolism in Pregnancy: Maternal Adaptations for Fetal Growth1

1973 • 167 citations

Studies on the Mechanism of Fatty Acid Synthesis

1961 • 161 citations

Maternal-fetal carnitine relationship and neonatal ketosis in the rat.

1976 • 151 citations

Cellular energy metabolism during fetal development

1972 • 150 citations

Regulation of hepatic acetyl coenzyme A carboxylase by insulin and glucagon.

1979 • 147 citations

Placental transfer of palmitic acid-1-C14 in rabbits

1962 • 138 citations

Development of Insulin and Glucagon Binding and the Adenylate Cyclase Response in Liver Membranes of the Prenatal, Postnatal, and Adult Rat: Evidence of Glucagon “Resistance”

1976 • 137 citations

BODY COMPOSITION OF INFANTS OF DIABETIC MOTHERS BY DIRECT ANALYSIS*

1963 • 135 citations

Inhibition of Rat-Liver Acetyl-Coenzyme-A Carboxylase by Palmitoyl-Coenzyme A. Formation of Equimolar Enzyme-Inhibitor Complex

1978 • 126 citations

Fatty acid synthesis in vivo in maternal and fetal tissues in the rat

1966 • 125 citations

Placental transfer of essential fatty acids in humans: venous-arterial difference for docosahexaenoic acid in fetal umbilical erythrocytes.

1990 • 121 citations

Bilirubin Metabolism in the Fetus*

1964 • 118 citations

Transfer of free fatty acids across the primate placenta

1969 • 109 citations

Short‐term effects of insulin and glucagon on lipid synthesis in isolated rat hepatocytes

1978 • 106 citations

Effect of Insulin on Growth and Biochemical Composition of the Rat Fetus

1967 • 104 citations

Transfer Across Perfused Human Placenta. II. Free Fatty Acids

1973 • 99 citations

METABOLIC ADJUSTMENTS IN NORMAL AND DIABETIC PREGNANCY

1981 • 95 citations

Incorporation of carbon atoms from glucose into free amino acids in brain under normal and altered conditions

1970 • 92 citations

Placental transport of free palmitic and linoleic acids in the guinea pig

1968 • 89 citations

Carnitine palmitoyltransferase activity and fatty acid oxidation by livers from fetal and neonatal rats

1970 • 87 citations

[Free fatty acids].

1967 • 85 citations

The Biological Basis of Reproductive and Developmental Medicine

1984 • 84 citations

Effect of Oxygen Deprivation on the Metabolism of Fetal and Adult Tissues

1958 • 82 citations

Glucose carbon recycling and oxidation in human newborns

1986 • 81 citations

Ketogenesis and malonyl coenzyme A content of isolated rat hepatocytes.

1978 • 80 citations

MINERAL GROWTH OF THE HUMAN FETUS

1934 • 78 citations

Inhibition of carnitine palmitoyl-CoA transferase activity and fatty acid oxidation by lactate and oxfenicine in cardiac muscle

1985 • 77 citations

Placental metabolism and transport of lipid.

1986 • 77 citations

Neonatal changes in the concentration of rat liver cyclic AMP and of serum glucose, free fatty acids, insulin, pancreatic, and total glucagon in man and in the rat.

1974 • 77 citations

Both insulin and epidermal growth factor stimulate fatty acid synthesis and increase phosphorylation of acetyl‐CoA carboxylase and ATP‐citrate lyase in isolated hepatocytes

1985 • 76 citations

The Role of Lactate as an Energy Substrate for the Brain during the Early Neonatal Period

1985 • 75 citations

MATERNAL AND F$OElig;TAL KETONE CONCENTRATIONS IN PLASMA AND URINE

1967 • 74 citations

The Gaseous Metabolism of the Newborn Infant

1957 • 73 citations

Marked acceleration of exogenous fatty acid incorporation into cellular triglycerides by fetuin.

1990 • 72 citations

Evidence that the sensitivity of carnitine palmitoyltransferase I to inhibition by malonyl-CoA is an important site of regulation of hepatic fatty acid oxidation in the fetal and newborn rabbit. Perinatal development and effects of pancreatic hormones in cultured rabbit hepatocytes

1990 • 70 citations

Insulin and Glucagon during the Perinatal Period: Secretion and Metabolic Effects on the Liver

1985 • 70 citations

Fetal fuels. I. Utilization of ketones by isolated tissues at various stages of maturation and maternal nutrition during late gestation

1977 • 69 citations

The transfer of free fatty acids across the human placenta

1985 • 68 citations

Plasma Membrane Fatty-Acid-Binding Protein in Human Placenta: Identification and Characterization

1995 • 65 citations

Plasma membrane fatty acid‐binding protein (FABP_pm) is exclusively located in the maternal facing membranes of the human placenta

1995 • 64 citations

Gestational Age Dependency of Essential Fatty Acids in Cord Plasma Cholesterol Esters and Triglycerides

1994 • 64 citations

INFLUENCE OF ENVIRONMENTAL TEMPERATURE AND ACIDOSIS ON LIPID MOBILIZATION IN THE HUMAN INFANT DURING THE FIRST TWO HOURS AFTER BIRTH

1971 • 60 citations

Transfer of fatty acids across the rabbit placenta.

1975 • 60 citations

The Effect of Pregnancy on the Control of Lipolysis in Fat Cells Isolated from Human Adipose Tissue

1975 • 59 citations

De novo fatty acid synthesis in developing rat lung

1982 • 58 citations

Fetal utilization of maternally derived ketone bodies for lipogenesis in the rat

1977 • 57 citations

CLINICAL OBSTETRICS AND GYNECOLOGY

1961 • 56 citations

Lipids, Lipoproteins and Apolipoproteins A<sub>I</sub> A<sub>II</sub>, B, C<sub>II</sub>, C<sub>III</sub> and E in Newborns

1991 • 49 citations

CONCENTRATIONS OF FREE FATTY ACIDS IN MATERNAL AND UMBILICAL CORD BLOOD DURING ELECTIVE CAESAREAN SECTION

1976 • 49 citations

The transfer of free fatty acids across the rabbit placenta.

1977 • 48 citations

Effects of Exogenous Insulin on the Rate of Fatty Acid Synthesis and Glucose C-14 Utilization in the Twenty-day Rat Fetus

1968 • 47 citations

Influences on fetal growth

1976 • 46 citations

Some Aspects of Fatty Acid Oxidation and Ketone Body Formation and Utilization during Development of the Rat

1973 • 44 citations

Placental Transfer of Non-Esterified Fatty Acids in Normal and Diabetic Pregnancy

1987 • 40 citations

Metabolism of Subcutaneous Adipose Tissue in the Immediate Postnatal Period of Human Newborns. 1. Developmental Changes in Lipolysis and Glycogen Content

1972 • 38 citations

Essential fatty acid status during early human development

1992 • 38 citations

Hepatic triglyceride hydrolysis and development of ketogenesis in rabbits

1985 • 37 citations

Ketosis in the Rat Fetus.

1958 • 36 citations

Fatty acids as energy sources

1975 • 36 citations

Fetal lung surfactant lipid synthesis from glycogen during organ culture

1986 • 35 citations

RESPIRATORY QUOTIENT AND METABOLIC RATE IN NORMAL FULL‐TERM AND SMALL‐FOR‐DATE NEWBORN INFANTS1

1970 • 35 citations

Transfer across Perfused Human Placenta. III. Effect of Chain Length on Transfer of Free Fatty Acids

1974 • 34 citations

Localization and regulation of the human very low density lipoprotein/apolipoprotein-E receptor: trophoblast expression predicts a role for the receptor in placental lipid transport

1995 • 33 citations

Decreased hepatic fatty acid oxidation at weaning in the rat is not linked to a variation of malonyl-CoA concentration.

1988 • 32 citations

Evidence that the development of hepatic fatty acid oxidation at birth in the rat is concomitant with an increased intramitochondrial CoA concentration

1986 • 31 citations

Comparison between the essential fatty acid status of preterm and full-term infants, measured in umbilical vessel walls

1995 • 31 citations

l-Lactate as a source of carbon for fatty acid synthesis in adult and foetal sheep

1981 • 29 citations

The relationship between hepatic low-density lipoprotein receptor activity and serum cholesterol level in the human fetus

1991 • 28 citations

Release of free fatty acids from adipose tissue obtained from newborn infants

1965 • 28 citations

In vitro metabolism of palmitic acid and glucose in the developing tissue of the rhesus monkey

1974 • 27 citations

Cellular energy metabolism during fetal development. III. Deficient acetyl-CoA synthetase, acetylcarnitine transferase and oxidation of acetate in the fetal bovine heart

1970 • 27 citations

Effects of dietary nutrients on lipogenic enzyme and mRNA activities in rat liver during induction

1986 • 26 citations

Prenatal Induction of Ketone-Body Enzymes in the Rat

1971 • 25 citations

Lipid metabolism in the fetal and neonatal rabbit

1966 • 25 citations

Studies on the Placental Hydrolysis and Transfer of Lipids to the Fetal Guinea Pig

1984 • 24 citations

Synthesis of C20 and C22 Polyunsaturated Fatty Acids by the Placenta of the Sheep

1985 • 23 citations

Serum hormones and metabolites in fetally decapitated pigs.

1984 • 23 citations

Multifunctional role for fetuin (fetal protein) in lipid transport

1991 • 23 citations

High Density Lipoprotein Particle Size Distribution in Cord Blood

1991 • 22 citations

The Biological Basis of Reproductive and Developmental Medicine

1983 • 21 citations

Fetal fuels. III: Ketone utilization by fetal hepatocyte.

1978 • 21 citations

Regulation of hepatic gene expression by lipogenic diet and thyroid hormone.

1986 • 21 citations

Placental Transfer of Free Fatty Acids: Importance of Fetal Albumin Concentration and Acid-Base Status

1993 • 21 citations

Influence of Exogenous Glucagon on Fetal Glucose Metabolism and Ketone Production

1983 • 20 citations

Increased Maternal-Fetal Transport of Fat in Diabetes Assessed by Polyunsaturated Fatty Acid Content in Fetal Lipids

1985 • 20 citations

Lipogenesis from Lactate in Fetal Rat Brain during Late Gestation

1993 • 18 citations

Hepatic mitochondrial fatty acid oxidation during the perinatal period in the rat

1983 • 18 citations

Fetal nutrition, metabolism and immunology; the role of the placenta

1985 • 17 citations

Placental transfer of free fatty acids: factors affecting transfer across the guinea-pig placenta.

1983 • 17 citations

Influence of the Pituitary on Lipolysis and Lipogenesis in Fetal Pig Adipose Tissue

1993 • 17 citations

Metabolism of Subcutaneous Adipose Tissue in the Immediate Postnatal Period of Human Newborns

1973 • 17 citations

Fatty acid synthesis from amino acids in sheep adipose tissue

1985 • 15 citations

Newly Recognized Lipid Carrier Proteins in Fetal Life

1991 • 15 citations

Hyperglycaemia induced by glucose infusion in the unrestrained pregnant rat: Effect on body weight and lipid synthesis in post-mature fetuses

1983 • 14 citations

Effects of altering umbilical flow and umbilical free fatty acid concentration on transfer of free fatty acids across the rabbit placenta.

1991 • 13 citations

Main Routes of Plasma Lactate Carbon Disposal in the Midgestation Fetal Lamb

1995 • 13 citations

Cellular Energy Metabolism

1990 • 12 citations

Octanoate metabolism in isolated hepatocytes and mitochondria from fetal, newborn and adult rabbit

1989 • 11 citations

Effect of maternal diet during late pregnancy on fetal lipid stores in rabbits.

1983 • 10 citations

Blood chemistry of human fetuses in the second and third trimesters

1990 • 9 citations

Metabolic Development of Porcine Fetal Adipose Tissue

1988 • 9 citations

Effects of Fat Mobilization on Liver Acetate Metabolism

1966 • 9 citations

Cellular energy metabolism during fetal development

1973 • 9 citations

Transfer of maternal plasma free fatty acids into the rat fetus.

1975 • 8 citations

Premature Appearance of Gluconeogenesis and Fatty Acid Oxidation in the Liver of the Postterm Rabbit Fetus

1988 • 8 citations

Stimulatory Effect of Calcitonin on Fatty Acid Synthesis in the Liver of Fed Rats

1985 • 7 citations

Quantitative Studies on the Fetal Lipid Metabolism in Rats: Liver Fatty Acid Esterification and Conversion into Carbon Dioxide, and Hepatic Output of Triglycerides and Phospholipids into Serum

1986 • 7 citations

Effect of Lactate on Glucose Incorporation into Fetal Lung Phospholipids

1988 • 7 citations

Insulin Stimulates Amino Acid and Lipid Metabolism in Isolated Fetal Rat Hepatocytes

1986 • 6 citations

Quantitative evaluation of the fetal fatty acid synthesis in the rat.

1978 • 6 citations

Lipid chain length alterations during placental transfer in the guinea pig.

1985 • 5 citations