Flanking AT-rich tracts cause a structural distortion in Z-DNA in plasmids.

THE CHEMISTRY AND BIOLOGY OF LEFT-HANDED Z-DNA

1984 • 1,149 citations

A hypothesis on a specific sequence-dependent conformation of DNA and its relation to the binding of the lac-repressor protein

1979 • 390 citations

Structures for the polynucleotide complexes Poly(dA)·Poly(dT) and Poly (dT)·Poly(dA)·Poly(dT)

1975 • 369 citations

Unusual DNA structures.

1988 • 309 citations

KMnO4 as a probe for lac promoter DNA melting and mechanism in vivo

1989 • 294 citations

Chemical probes of DNA conformation: detection of Z-DNA at nucleotide resolution

1985 • 286 citations

Sequence-dependent helical periodicity of DNA

1981 • 282 citations

DNA supercoiling promotes formation of a bent repression loop in lac DNA

1987 • 252 citations

Nucleosomes will not form on double-stranded RNA or over poly(dA)-poly(dT) tracts in recombinant DNA

1981 • 244 citations

Stabilization of Z DNA in Vivo by Localized Supercoiling

1989 • 220 citations

Left-Handed DNA in Vivo

1987 • 214 citations

DNA Structure and Gene Regulation

1980 • 200 citations

Facile cruciform formation by an (A-T)34 sequence from a Xenopus globin gene

1985 • 186 citations

Diethyl pyrocarbonate: a chemical probe for secondary structure in negatively supercoiled DNA.

1985 • 169 citations

The facile generation of covalently closed, circular DNAs with defined negative superhelical densities

1982 • 139 citations

Conditions which cause the right-handed to left-handed DNA conformational transitions. Evidence for several types of left-handed DNA structures in solution.

1982 • 138 citations

Transmission of stability (telestability) in deoxyribonucleic acid. Physical and enzymatic studies on the duplex block polymer d(C15A15) - d(T15G15).

1975 • 134 citations

Monoclonal antibodies recognize different parts of Z-DNA.

1982 • 133 citations

Transition of a cloned d(AT)n-d(AT)n tract to a cruciformin vivo

1985 • 130 citations

The supercoil-stabilised cruciform of ColE1 is hyper-reactive to osmium tetroxide.

1984 • 120 citations

S1 nuclease recognizes DNA conformational junctions between left-handed helical (dT-dG n. dC-dA)n and contiguous right-handed sequences.

1984 • 119 citations

(A-T)_ntracts embedded in random sequence DNA — formation of a structure which is chemically reactive and torsionally deformable

1986 • 113 citations

Internal motions in DNA.

1979 • 112 citations

A dominant influence of flanking sequences on a local structural transition in DNA

1986 • 104 citations

An alternating conformation characterizes the phosphodiester backbone of poly(dA-dT) in solution.

1979 • 103 citations

The B- to Z-DNA equilibrium in vivo is perturbed by biological processes.

1988 • 90 citations

Structural perturbation in supercoiled DNA: hypersensitivity to modification by a single-strand-selective chemical reagent conferred by inverted repeat sequences

1983 • 73 citations

Site-specific OsO4 modification of the B-Z junctions formed at the (dA-dC)32 region in supercoiled DNA.

1986 • 72 citations

1H nuclear magnetic resonance investigation of flexibility in DNA.

1979 • 71 citations

Hhalmethylase and restriction endonuclease as probes for B to Z DNA conformational changes in d(GCGC) sequences

1984 • 71 citations

A Structural Transition in d(AT)_n·d(AT)_nInserts within Superhelical DNA

1985 • 69 citations

High-resolution analysis of lac transcription complexes inside cells

1986 • 61 citations

Recognition of the Structural Distortions at the Junctions Between B and Z Segments in Negatively Supercoiled DNA by Osmium Tetroxide

1985 • 58 citations

Conformational transitions in oriented fibres of the synthetic polynucleotide poly[d(AT)]·poly[d(AT)] double helix

1983 • 56 citations

Left-Handed Z-DNA and Genetic Recombination

1989 • 54 citations

The role of DNA sequence in the formation of Z-DNA versus cruciforms in plasmids.

1988 • 52 citations

A two-state conformational equilibrium for alternating (A-T)n sequences in negatively supercoiled DNA

1987 • 52 citations

The role of sequence in the stabilization of left-handed DNA helices in vitro and in vivo

1988 • 47 citations

Unusual conformational effect exerted by Z-DNA upon its neighboring sequences.

1987 • 45 citations

Tetracycline promoter mutations decrease non-B DNA structural transitions, negative linking differences and deletions in recombinant plasmids in Escherichia coli

1989 • 44 citations

Reaction conditions affect the specificity of bromoacetaidehyde as a probe for DNA cruciforms and B—Z junctions

1987 • 44 citations

Characteristics of Z-DNA helices formed by imperfect (purine-pyrimidine) sequences in plasmids.

1988 • 43 citations

(AT)n is an interspersed repeat in the Xenopus genome.

1985 • 41 citations

Thermodynamic parameters are sequence-dependent for the supercoil-induced B to Z transition in recombinant plasmids.

1986 • 40 citations

13C NMR Study of Conformation and Mobility of 145-Base-Pair Poly(dA-dT) . poly(dA-dT) in Solution

1981 • 38 citations

Long range structural communication between sequences in supercoiled DNA. Sequence dependence of contextual influence on cruciform extrusion mechanism.

1988 • 34 citations