AU RNA-binding factors differ in their binding specificities and affinities.

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Regulation of Lymphokine Messenger RNA Stability by a Surface-Mediated T Cell Activation Pathway

1989 • 910 citations

Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation

1988 • 707 citations

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

1988 • 691 citations

CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines.

1989 • 662 citations

T-Cell Proliferation Involving the CD28 Pathway Is Associated witH Cyclosporine-Resistant Interleukin 2 Gene Expression

1987 • 522 citations

Identification of an AUUUA-Specific Messenger RNA Binding Protein

1989 • 515 citations

A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA

1989 • 511 citations

Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level.

1990 • 495 citations

An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

1991 • 484 citations

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro.

1989 • 472 citations

Estrogen stabilizes vitellogenin mRNA against cytoplasmic degradation

1983 • 440 citations

Sequence-specific RNA binding by the HIV-1 Rev protein

1989 • 384 citations

Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro

1989 • 377 citations

DNA binding of purified transcription factor NF-kappa B. Affinity, specificity, Zn2+ dependence, and differential half-site recognition.

1991 • 349 citations

Translational Blockade Imposed by Cytokine-Derived UA-Rich Sequences

1989 • 347 citations

Rapid Cytoplasmic Turnover of c-myc mRNA: Requirement of the 3′ Untranslated Sequences

1987 • 302 citations

An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3' untranslated region of lymphokine mRNA.

1991 • 293 citations

A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs.

1991 • 268 citations

GM-CSF and oncogene mRNA stabilities are independently regulated in trans in a mouse monocytic tumor

1988 • 227 citations

The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.

1991 • 222 citations

A redox switch and phosphorylation are involved in the post-translational up-regulation of the adenosine-uridine binding factor by phorbol ester and ionophore.

1991 • 184 citations

The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation.

1987 • 177 citations

Regulation of c-myc mRNA Stability In Vitro by a Labile Destabilizer with an Essential Nucleic Acid Component

1989 • 172 citations

The AU-rich sequences in the 3' untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids.

1991 • 170 citations

The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein.

1989 • 144 citations

Regulation of Granulocyte- and Monocyte-colony Stimulating Factor mRNA Levels in Human Blood Monocytes Is Mediated Primarily at a Post-transcriptional Level

1989 • 139 citations

Multiple determinants of eukaryotic mRNA stability.

1989 • 118 citations

Mechanisms regulating the level of IL-2 mRNA in T lymphocytes.

1988 • 115 citations

Cytokine messenger RNA stability is enhanced in tumor cells

1991 • 65 citations

Stability of IL-2 mRNA in T lymphocytes is controlled by a protein kinase C-regulated mechanism

1990 • 12 citations