Mistletoe viscotoxins increase natural killer cell‐mediated cytotoxicity

Biology of Natural Killer Cells

1989 • 2,970 citations

Surface IgM-kappa specificity on a Burkitt lymphoma cell in vivo and in derived culture lines.

1968 • 833 citations

Characterization of a human cell line (NK-92) with phenotypical and functional characteristics of activated natural killer cells.

1994 • 671 citations

The cytosensor microphysiometer: biological applications of silicon technology

1992 • 631 citations

Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis

2000 • 358 citations

On guard—activating NK cell receptors

2001 • 350 citations

Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia.

1996 • 350 citations

Surface markers on human b and t lymphocytes. VI. Cytotoxicity against cell lines as a functional marker for lymphocyte subpopulations

1975 • 312 citations

Cell Biology of Cytotoxic and Helper T Cell Functions: Immunofluorescence Microscopic Studies of Single Cells and Cell Couples

1989 • 296 citations

Thionins: properties, possible biological roles and mechanisms of action

1994 • 221 citations

Mutations that impair a posttranscriptional step in expression of HLA-A and -B antigens.

1985 • 183 citations

Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type.

1993 • 178 citations

Human NK-cell receptors

2000 • 176 citations

The effect of an adjuvant mistletoe treatment programme in resected head and neck cancer patients

2001 • 174 citations

Chemical Synthesis and Biological Activity of Bromohydrin Pyrophosphate, a Potent Stimulator of Human γδ T Cells

2001 • 148 citations

Thionins: Plant Peptides that Modify Membrane Permeability in Cultured Mammalian Cells

1981 • 144 citations

Signaling pathways engaged by NK cell receptors: double concerto for activating receptors, inhibitory receptors and NK cells

2000 • 122 citations

Potassium channels mediate killing by human natural killer cells.

1986 • 101 citations

The Cytotoxic Plant Protein, β-Purothionin, Forms Ion Channels in Lipid Membranes

2000 • 91 citations

Immunomodulatory Effects of Iscador: A <i>Viscum album</i> Preparation

1986 • 90 citations

Immunomodulatory Activity of a Peptide Isolated fromViscum AlbumExtract (NSC 635 089)

1992 • 76 citations

Cloning of a breakpoint cluster region at band 3q27 involved in human non‐Hodgkin's lymphoma

1993 • 70 citations

AViscum album oligosaccharide activating human natural cytotoxicity is an interferon γ inducer

1990 • 69 citations

Mechanism of stimulation of human natural killer cytotoxicity by arabinogalactan fromLarix occidentalis

1993 • 66 citations

Functional Studies of Fc Receptor-Bearing Human Lymphocytes: Effect of Treatment with Proteolytic Enzymes

1979 • 66 citations

Cytotoxicity of Different Viscotoxins and Extracts from the European Subspecies ofViscum albumL.

1996 • 65 citations

Characterization of cytotoxic proteins from mistletoe (Viscum album L.)

1990 • 64 citations

An Overview on Anticancer Activities of theViscum AlbumExtract Isorel^®

2001 • 62 citations

Daudi lymphoma killing triggers the programmed death of cytotoxic V gamma 9/V delta 2 T lymphocytes.

1995 • 61 citations

Correlation of immune cell activities and beta-endorphin release in breast carcinoma patients treated with galactose-specific lectin standardized mistletoe extract

1999 • 56 citations

Potassium channels in human NK cells are involved in discrete stages of the killing process.

1986 • 55 citations

Amino Acid Sequence, S-S Bridge Arrangement and Distribution in Plant Tissues of Thionins from Viscum album

1997 • 54 citations

An immunologically active arabinogalactan from Viscum album ‘berries’

1988 • 48 citations

Amino Acid Sequence and Disulphide-bridge Pattern of three gamma-Thionins from Sorghum bicolor

1995 • 46 citations

Treatment of advanced pancreatic cancer with mistletoe: results of a pilot trial.

1996 • 46 citations

Comparative study on the cytotoxic effect of viscotoxin and mistletoe lectin on tumour cells in culture

1995 • 44 citations

Signaling for cytotoxicity

2000 • 43 citations

Modes of membrane interaction of a natural cysteine-rich peptide: viscotoxin A3

2002 • 42 citations

Synergistic action of a plant rhamnogalacturonan enhancing antitumor cytotoxicity of human natural killer and lymphokine-activated killer cells: chemical specificity of target cell recognition.

1990 • 41 citations

Cytotoxic effects of the components in heat-treated mistletoe ( Viscum album )

1999 • 41 citations

The cytotoxic effect of mistletoe lectins I, II and III on sensitive and multidrug resistant human colon cancer cell lines in vitro

2002 • 40 citations

A high-resolution view of NK-cell receptors: structure and function

2000 • 36 citations

Stimulation of the specific immune system by mistletoe extracts

1997 • 35 citations

Mediation of human NK-activity by components in extracts of Viscum album

1987 • 35 citations

Chemical specificity of effector cell/tumor cell bridging by a Viscum album rhamnogalacturonan enhancing cytotoxicity of human NK cells

1990 • 33 citations

Biochemical characterization of a component in extracts of Viscum album enhancing human NK cytotoxicity

1989 • 32 citations

Mistletoe Lectin I-Induced Effects on Human Cytotoxic Lymphocytes. I. Synergism with Il-2 in the Induction of Enhanced Lak Cytotoxicity

1998 • 30 citations

Mistletoe therapy for human cancer: the role of the natural killer cells

1997 • 29 citations

Über Harnstoff‐ und Tetrahydroimidazol‐Derivate von D‐Glucosamin

1961 • 29 citations

Mistletoe extract-induced effects on immunocompetent cells: in vitro studies

1997 • 27 citations

Activation of human γδ T-cell by heat-treated mistletoe plant extracts

1996 • 26 citations

[The mistletoe myth--claims, reality and provable perspectives].

1996 • 9 citations

Future developments with ??Tomudex?? (raltitrexed)

1997 • 8 citations

[Immunomodulating mistletoe therapy by lectin standardization: a double-edged sword?].

1999 • 3 citations