Induction of platelet-derived growth factor alpha- and beta-receptor mRNA and protein by platelet-derived growth factor BB.

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

1973 • 3,279 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Oncogenes and signal transduction

1991 • 2,816 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

1985 • 1,107 citations

TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

1990 • 756 citations

Interleukin-1 Mitogenic Activity for Fibroblasts and Smooth Muscle Cells Is Due to PDGF-AA

1989 • 648 citations

Two Different Subunits Associate to Create Isoform-Specific Platelet-derived Growth Factor Receptors

1989 • 633 citations

Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes

1989 • 610 citations

Complexity of the early genetic response to growth factors in mouse fibroblasts.

1988 • 579 citations

Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.

1988 • 514 citations

Platelet-derived growth factor: mechanism of action and possible in vivo function.

1990 • 491 citations

Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.

1983 • 446 citations

cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor.

1989 • 413 citations

Dimerization of B-type Platelet-derived Growth Factor Receptors Occurs After Ligand Binding and Is Closely Associated with Receptor Kinase Activation

1989 • 366 citations

Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor

1983 • 352 citations

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules.

1988 • 338 citations

Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class.

1988 • 314 citations

Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation.

1988 • 288 citations

Epidermal growth factor regulates the expression of its own receptor.

1985 • 253 citations

Platelet-derived growth factor synthesis in mesangial cells: induction by multiple peptide mitogens.

1989 • 240 citations

Possible positive autocrine feedback in the prereplicative phase of human fibroblasts

1987 • 234 citations

Ligand-induced dimerization of the platelet-derived growth factor receptor

1989 • 190 citations

Epidermal growth factor (EGF) stimulates EGF receptor synthesis.

1986 • 190 citations

Identification and Structural Analysis of the A Type Receptor for Platelet-derived Growth Factor

1989 • 179 citations

Comparison of Biological Properties and Transforming Potential of Human PDGF-A and PDGF-B Chains

1988 • 178 citations

Rat Brain Capillary Endothelial Cells Express Functional PDGF B-Type Receptors

1989 • 153 citations

Transcriptional regulation of the A and B chain genes of platelet-derived growth factor in microvascular endothelial cells.

1988 • 138 citations

The Effects of Platelet-Derived Growth Factor in Cultured Microvessel Endothelial Cells*

1989 • 137 citations

Differential regulation of expression of two platelet-derived growth factor receptor subunits by transforming growth factor-β

1989 • 136 citations

Cell-specific cyclic AMP-mediated induction of the PDGF receptor.

1990 • 134 citations

Regulated expression of the platelet-derived growth factor A chain gene in microvascular endothelial cells.

1987 • 126 citations

Expression of Three Recombinant Homodimeric Isoforms of PDGF inSaccharomyces cerevisiae: Evidence for Difference in Receptor Binding and Functional Activities

1989 • 126 citations

Bi‐functional action of transforming growth factor‐β on DNA synthesis in early passage human fetal fibroblasts

1986 • 121 citations

Growth factor‐induced proliferation of human fibroblasts in serum‐free culture depends on cell density and extracellular calcium concentration

1984 • 95 citations

Ligand-induced interaction between .alpha.- and .beta.-type platelet-derived growth factor (PDGF) receptors: role of receptor heterodimers in kinase activation

1991 • 93 citations

Purification of the receptor for platelet-derived growth factor from porcine uterus.

1987 • 83 citations

Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects.

1988 • 71 citations

Density-Dependent Inhibition of Cell Growth by Transforming Growth Factor-β1 in Normal Human Fibroblasts

1988 • 51 citations