A distant upstream site involved in the negative regulation of the Escherichia coli ompF gene

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

Experiments With Gene Fusions

1984 • 2,487 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu

1976 • 1,895 citations

Protein phosphorylation and regulation of adaptive responses in bacteria

1989 • 1,495 citations

COMMUNICATION MODULES IN BACTERIAL SIGNALING PROTEINS

1992 • 1,449 citations

Physiological and genetic responses of bacteria to osmotic stress

1989 • 1,433 citations

Integration host factor: A protein for all reasons

1988 • 501 citations

Control site location and transcriptional regulation in Escherichia coli

1991 • 497 citations

Two-component regulatory systems responsive to environmental stimuli share strongly conserved domains with the nitrogen assimilation regulatory genes ntrB and ntrC.

1986 • 464 citations

The ompB locus and the regulation of the major outer membrane porin proteins of Escherichia coli K12

1981 • 329 citations

Genetic analysis of the ompB locus in Escherichia coli K-12

1981 • 301 citations

PROKARYOTIC SIGNAL TRANSDUCTION MEDIATED BY SENSOR AND REGULATOR PROTEIN PAIRS

1989 • 295 citations

Phosphorylation and dephosphorylation of a bacterial transcriptional activator by a transmembrane receptor.

1989 • 271 citations

Phosphorylation of OmpR by the osmosensor EnvZ modulates expression of the ompF and ompC genes in Escherichia coli.

1989 • 258 citations

Signal transduction and gene regulation through the phosphorylation of two regulatory components: the molecular basis for the osmotic regulation of the porin genes

1990 • 230 citations

Influence of molecular size and osmolarity of sugars and dextrans on the synthesis of outer membrane proteins O-8 and O-9 of Escherichia coli K-12

1979 • 203 citations

MULTIPARTITE GENETIC CONTROL ELEMENTS: COMMUNICATION BY DNA LOOP

1989 • 188 citations

EnvZ controls the concentration of phosphorylated OmpR to mediate osmoregulation of the porin genes

1991 • 186 citations

The role of integration host factor In gene expression in Escherichia coli

1992 • 183 citations

Transfer of Phosphoryl Group between Two Regulatory Proteins Involved in Osmoregulatory Expression of the ompF and ompC Genes in Escherichia coli

1989 • 179 citations

cis-acting ompF mutations that result in OmpR-dependent constitutive expression

1991 • 175 citations

Localization and membrane topology of EnvZ, a protein involved in osmoregulation of OmpF and OmpC in Escherichia coli.

1987 • 174 citations

EnvZ, a transmembrane environmental sensor of Escherichia coli K-12, is phosphorylated in vitro

1988 • 164 citations

A bacterial environmental sensor that functions as a protein kinase and stimulates transcriptional activation.

1989 • 152 citations

Evidence for the Physiological Importance of the Phosphotransfer between the Two Regulatory Components, EnvZ and OmpR, in Osmoregulation in Escherichia coli

1989 • 150 citations

Phosphorylation of a Bacterial Activator Protein, OmpR, by a Protein Kinase, EnvZ, Results in Stimulation of Its DNA-Binding Ability1

1989 • 138 citations

DNA looping

1992 • 136 citations

Interaction of a transcriptional activator, OmpR, with reciprocally osmoregulated genes, ompF and ompC, of Escherichia coli.

1986 • 130 citations

Environmentally Regulated Gene Expression for Membrane Proteins in Escherichia coli

1988 • 130 citations

Genetic analysis of the switch that controls porin gene expression in Escherichia coli K-12

1989 • 123 citations

The tolC locus of Escherichia coli affects the expression of three major outer membrane proteins

1982 • 116 citations

Suppressor mutations in rpoA suggest that OmpR controls transcription by direct interaction with the alpha subunit of RNA polymerase

1991 • 113 citations

Open reading frame expression vectors: a general method for antigen production in Escherichia coli using protein fusions to beta-galactosidase.

1983 • 108 citations

Purification and characterization of the OmpR protein, a positive regulator involved in osmoregulatory expression of the ompF and ompC genes in Escherichia coli.

1986 • 104 citations

Role of micF in the tolC-mediated regulation of OmpF, a major outer membrane protein of Escherichia coli K-12

1987 • 99 citations

Identification of the DNA-binding domain of the OmpR protein required for transcriptional activation of the ompF and ompC genes of Escherichia coli by in vivo DNA footprinting

1989 • 94 citations

In vivo phosphorylation of OmpR, the transcription activator of the ompF and ompC genes in Escherichia coli

1990 • 85 citations

Interaction of OmpR, a positive regulator, with the osmoregulated ompC and ompF genes of Escherichia coli. Studies with wild-type and mutant OmpR proteins.

1988 • 85 citations

Phosphorylation of a bacterial activator protein, OmpR, by a protein kinase, EnvZ, stimulates the transcription of the ompF and ompC genes in Escherichia coli

1990 • 83 citations

Static bend of DNA helix at the activator recognition site of the ompF promoter in Escherichia coli

1987 • 72 citations

cis-acting sites required for osmoregulation of ompF expression in Escherichia coli K-12

1986 • 64 citations

Signal transduction in bacteria: kinases that control gene expression.

1990 • 63 citations

Novel rpoA mutation that interferes with the function of ompR and envZ, positive regulators of the ompF and ompC genes that code for outer-membrane proteins in Escherichia coli K12

1987 • 55 citations

Altered osmoregulation of ompF in integration host factor mutants of Escherichia coli

1988 • 53 citations

Molecular analysis of the signaling pathway between EnvZ and OmpR in Escherichia coli

1992 • 45 citations

In vitro interactions of integration host factor with the ompF promoter-regulatory region of Escherichia coli

1992 • 37 citations

Mutations in the alpha subunit of RNA polymerase that affect the regulation of porin gene transcription in Escherichia coli K-12

1993 • 31 citations

The EnvZ protein ofSalmonella typhimuriumLT-2 andEscherichia coliK-12 is located in the cytoplasmic membrane

1986 • 26 citations

Identification of a temperature-sensitive asparaginyl-transfer ribonucleic acid synthetase mutant of Escherichia coli

1977 • 24 citations

Molecular Analysis by Deletion and Site-Directed Mutagenesis of the cis-Acting Upstream Sequence Involved in Activation of the ompF Promoter in Escherichia coli1

1989 • 11 citations

The asparaginyl‐tRNA synthetase gene encodes one of the complementing factors for thermosensitive translation in the Escherichia coli mutant strain, N4316

1992 • 8 citations