Targeting gene-modified hematopoietic cells to the central nervous system: Use of green fluorescent protein uncovers microglial engraftment

Bone marrow cells regenerate infarcted myocardium

2001 • 5,234 citations

Microglia: a sensor for pathological events in the CNS

1996 • 4,309 citations

‘Green mice’ as a source of ubiquitous green cells

1997 • 2,586 citations

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo

2000 • 2,366 citations

Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow

2000 • 1,859 citations

From Marrow to Brain: Expression of Neuronal Phenotypes in Adult Mice

2000 • 1,709 citations

Perivascular Microglial Cells of the CNS Are Bone Marrow-Derived and Present Antigen in Vivo

1988 • 1,451 citations

Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice

1997 • 1,020 citations

A Novel Geneiba1in the Major Histocompatibility Complex Class III Region Encoding an EF Hand Protein Expressed in a Monocytic Lineage

1996 • 813 citations

Turnover of resident microglia in the normal adult mouse brain

1992 • 679 citations

Reduced Brain Edema and Infarction Volume in Mice Lacking the Neuronal Isoform of Nitric Oxide Synthase after Transient MCA Occlusion

1996 • 422 citations

Bone Marrow-derived Elements in the Central Nervous System: An Immunohistochemical and Ultrastructural Survey of Rat Chimeras

1992 • 395 citations

Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation

2000 • 387 citations

Mature microglia resemble immature antigen-presenting cells

1998 • 339 citations

Kinetics of Central Nervous System Microglial and Macrophage Engraftment: Analysis Using a Transgenic Bone Marrow Transplantation Model

1997 • 336 citations

Retroviral-Mediated Transfer of the Green Fluorescent Protein Gene Into Murine Hematopoietic Cells Facilitates Scoring and Selection of Transduced Progenitors In Vitro and Identification of Genetically Modified Cells In Vivo

1997 • 230 citations

Cells expressing human glucocerebrosidase from a retroviral vector repopulate macrophages and central nervous system microglia after murine bone marrow transplantation

1994 • 166 citations

Neuronal MCP-1 Expression in Response to Remote Nerve Injury

2001 • 127 citations

Mature monocytic cells enter tissues and engraft

1998 • 110 citations

Sustained High-Level Reconstitution of the Hematopoietic System by Preselected Hematopoietic Cells Expressing a Transduced Cell-Surface Antigen

1997 • 80 citations

Distribution and Characterization of GFP+ Donor Hematogenous Cells in Twitcher Mice after Bone Marrow Transplantation

2000 • 73 citations

Regulation of Microglia by CD4⁺ and CD8⁺ T Cells: Selective Analysis in CD45‐congenic Normal and Toxoplasma gondii‐infected Bone Marrow Chimeras

2001 • 38 citations

Region-specific activation of microglial cells in the rat septal complex following fimbria-fornix transection

1998 • 24 citations

Gene-marked autologous hematopoietic stem cell transplantation of autoimmune disease.

2000 • 22 citations

Reply to “Human neural progenitor cells: better blue than green?”

2000 • 10 citations