Selective Mediation of Nerve Injury-Induced Tactile Hypersensitivity by Neuropeptide Y

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Quantitative assessment of tactile allodynia in the rat paw

1994 • 6,953 citations

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

1988 • 4,963 citations

AChE-stained horizontal sections of the rat brain in stereotaxic coordinates

1980 • 4,422 citations

Classification of Chronic Pain: Descriptions of Chronic Pain Syndromes and Definitions of Pain Terms

1994 • 3,265 citations

An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

1992 • 3,001 citations

Efficient Analysis of Experimental Observations

1980 • 2,012 citations

Neuroanatomy of the Pain System and of the Pathways That Modulate Pain

1997 • 882 citations

H1-Receptor Antagonists

1994 • 757 citations

Myelinated afferents signal the hyperalgesia associated with nerve injury

1988 • 565 citations

Dynamic and static components of mechanical hyperalgesia in human hairy skin

1992 • 510 citations

Potent Analgesic Effects of GDNF in Neuropathic Pain States

2000 • 506 citations

Nociceptor modulated central sensitization causes mechanical hyperalgesia in acute chemogenic and chronic neuropathic pain

1994 • 469 citations

Tactile allodynia in the absence of C-fiber activation: altered firing properties of DRG neurons following spinal nerve injury

2000 • 433 citations

Properties of afferent nerve impulses originating from a neuroma

1974 • 422 citations

Spontaneous discharge originates in the dorsal root ganglion at the onset of a painful peripheral neuropathy in the rat

1992 • 419 citations

Onset of a painful peripheral neuropathy in rat: a partial and differential deafferentation and spontaneous discharge in A beta and A delta primary afferent neurons

1992 • 367 citations

An immunohistochemical study of neuronal populations containing neuropeptides or γ-aminobutyrate within the superficial layers of the rat dorsal horn

1981 • 364 citations

Increased neuropeptide Y (NPY)-like immunoreactivity in rat sensory neurons following peripheral axotomy

1991 • 357 citations

Time-Dependent Descending Facilitation from the Rostral Ventromedial Medulla Maintains, But Does Not Initiate, Neuropathic Pain

2002 • 343 citations

μ-Opioid receptor mRNA expression in the rat CNS: comparison to μ-receptor binding

1994 • 298 citations

Subtype selectivity of the novel nonpeptide neuropeptide Y Y1 receptor antagonist BIBO 3304 and its effect on feeding in rodents

1998 • 254 citations

Visceral nociceptive input into the ventral posterolateral nucleus of the thalamus: a new function for the dorsal column pathway

1996 • 235 citations

Neuropathic pain and injured nerve: Peripheral mechanisms

1991 • 228 citations

Pelvic visceral input into the nucleus gracilis is largely mediated by the postsynaptic dorsal column pathway

1996 • 227 citations

The distribution and origin of a novel brain peptide, neuropeptide Y, in the spinal cord of several mammals

1984 • 223 citations

Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats

1999 • 216 citations

Is there a pathway in the posterior funiculus that signals visceral pain?

1996 • 205 citations

Spontaneous activity of axotomized afferent neurons after L5 spinal nerve injury in rats

2000 • 204 citations

Detection of static and dynamic components of mechanical allodynia in rat models of neuropathic pain: are they signalled by distinct primary sensory neurones?

1999 • 200 citations

BIIE0246: A selective and high affinity neuropeptide Y Y2 receptor antagonist

1999 • 192 citations

Down-regulation of μ-opioid receptors in rat and monkey dorsal root ganglion neurons and spinal cord after peripheral axotomy

1997 • 191 citations

Effects of peripheral nerve injuries and tissue inflammation on the levels of neuropeptide Y-like immunoreactivity in rat primary afferent neurons

1992 • 189 citations

Presence of avian pancreatic polypeptide-like immunoreactivity in catecholamine and methionine-enkephalin-containing neurones within the central nervous system

1981 • 186 citations

The antinociceptive effects of spinally administered neuropeptide Y in the rat: systematic studies on structure-activity relationship.

1991 • 185 citations

Characteristics of ectopic discharges in a rat neuropathic pain model

2000 • 184 citations

Characterization of the antiallodynic efficacy of morphine in a model of neuropathic pain in rats

1995 • 180 citations

Systemic and supraspinal, but not spinal, opiates suppress allodynia in a rat neuropathic pain model

1995 • 179 citations

Primary sensory neurons exhibit altered gene expression in a rat model of neuropathic pain

1994 • 176 citations

The loss of antinociceptive efficacy of spinal morphine in rats with nerve ligation injury is prevented by reducing spinal afferent drive

1995 • 149 citations

Quantification of axotomy‐induced alteration of neuropeptide mRNAs in dorsal root ganglion neurons with special reference to neuropeptide Y mRNA and the effects of neonatal capsaicin treatment

1993 • 146 citations

Surgical interruption of a midline dorsal column visceral pain pathway

1997 • 144 citations

Nerve injury-induced tactile allodynia is mediated via ascending spinal dorsal column projections

2001 • 128 citations

Anxiolytic-like effect of neuropeptide Y (NPY), but not other peptides in an operant conflict test

1992 • 128 citations

Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system1Published on the World Wide Web on 4 December 1997.1

1998 • 125 citations

Impulses in dorsal spinal nerve rootlets in cats and rabbits arising from dorsal root ganglia isolated from the periphery

1974 • 120 citations

Are there separate central nervous system pathways for touch and pain?

1995 • 115 citations

Ascending projections from the area around the spinal cord central canal: APhaseolus vulgaris leucoagglutinin study in rats

1999 • 114 citations

Large Calibre Primary Afferent Neurons Projecting to the Gracile Nucleus Express Neuropeptide Y after Sciatic Nerve Lesions: an Immunohistochemical and In Situ Hybridization Study in Rats

1993 • 108 citations

GABAergic Neurons that Contain Neuropeptide Y Selectively Target Cells with the Neurokinin 1 Receptor in Laminae III and IV of the Rat Spinal Cord

1999 • 103 citations

Neuropathic Pain Syndromes, with Special Reference to Causalgia and Reflex Sympathetic Dystrophy

1986 • 103 citations

Regulation of galanin and neuropeptide Y in dorsal root ganglia and dorsal horn in rat mononeuropathic models: possible relation to tactile hypersensitivity

1999 • 97 citations

Ultrastructural studies on peptides in the dorsal horn of the spinal cord—I. Co-existence of galanin with other peptides in primary afferents in normal rats

1993 • 96 citations

Avian pancreatic polypeptide (APP) immunoreactive neurons in the spinal cord and spinal trigeminal nucleus

1981 • 89 citations

The anterior pretectal nucleus: a proposed role in sensory processing

1993 • 89 citations

Cholecystokinins in the central nervous system and neurohypophysis

1981 • 88 citations

Loss of antiallodynic and antinociceptive spinal/supraspinal morphine synergy in nerve-injured rats: restoration by MK-801 or dynorphin antiserum

1999 • 88 citations

Antihyperalgesic effects of intrathecal neuropeptide Y during inflammation are mediated by Y1 receptors

2002 • 84 citations

Nerve injury increases an excitatory action of neuropeptide Y and Y2-agonists on dorsal root ganglion neurons

1999 • 76 citations

Distribution of neuropeptide Y-like immunoreactivity and its relationship to FMRF-amide-like immunoreactivity in the sixth lumbar and first sacral spinal cord segments of the rat

1985 • 75 citations

Dorsal column lesions reverse the reduction of homecage activity in rats with pancreatitis

1997 • 74 citations

Neurobehavioral profile of neuropeptide Y

1991 • 74 citations

Neuropeptide Y receptor(s) mediating feeding in the rat: characterization with antagonists

2000 • 72 citations

The Cells of Origin of the Dorsal Column Postsynaptic Projection in the Lumbosacral Enlargements of Cats and Monkeys

1983 • 70 citations

Potent and selective tools to investigate neuropeptide Y receptors in the central and peripheral nervous systems: BIBO3304 (Y1) and CGP71683A (Y5)

2000 • 67 citations

Expression of peptides, nitric oxide synthase and NPY receptor in trigeminal and nodose ganglia after nerve lesions

1996 • 65 citations

Dorsal column-thalamic pathway is involved in thalamic hyperexcitability following peripheral nerve injury: a lesion study in rats with experimental mononeuropathy

2000 • 62 citations

The differential synaptic organization of the spinal and lemniscal projections to the ventrobasal complex of the rat thalamus. Evidence for convergence of the two systems upon single thalamic neurons

1987 • 59 citations

Do nociceptive signals from the pancreas travel in the dorsal column?

2001 • 58 citations

The effects of intrathecal neuropeptide Y on the spinal nociceptive flexor reflex in rats with intact sciatic nerves and after peripheral axotomy

1994 • 55 citations

Neuropeptide Y Y5 receptor antagonist CGP71683A: the effects on food intake and anxiety-related behavior in the rat

2001 • 54 citations

NPY-like immunoreactivity in sensory nerve fibers in rat sciatic neuroma

1992 • 53 citations

Upregulation of brain-derived neurotrophic factor and neuropeptide Y in the dorsal ascending sensory pathway following sciatic nerve injury in rat

1999 • 51 citations

Agonists for neuropeptide Y receptor subtypes NPY-1 and NPY-2 have opposite actions on rat nodose neuron calcium currents

1993 • 51 citations

Cell size-specific appearance of neuropeptide Y in the trigeminal ganglion following peripheral axotomy of different branches of the mandibular nerve of the rat

1993 • 50 citations

Antinociceptive effects of dorsal column stimulation in the rat: involvement of the anterior pretectal nucleus.

1989 • 50 citations

Antinociceptive effects of neuropeptide Y and related peptides in mice

1996 • 49 citations

Inhibition of amphetamine- and apomorphine-induced behavioural effects by neuropeptide Y Y1 receptor antagonist BIBO 3304

2000 • 47 citations

Pre- and postsynaptic location of mu, delta and kappa opioid receptors in the superficial layers of the dorsal horn of the rat spinal cord.

1990 • 42 citations

The effect of intrathecal selective agonists of Y1 and Y2 neuropeptide Y receptors on the flexor reflex in normal and axotomized rats

1999 • 38 citations

Alterations in neuropeptide Y, tyrosine hydroxylase, and Y-receptor subtype distribution following spinal nerve injury to rats

1999 • 31 citations

Partial sciatic nerve ligation induced more dramatic increase of neuropeptide Y immunoreactive axonal fibers in the gracile nucleus of middle-aged rats than in young adult rats

2000 • 26 citations

The expression of different cytochemical markers in normal and axotomised dorsal root ganglion cells projecting to the nucleus gracilis in the adult rat

1990 • 23 citations

Effect on nociception of intracerebroventricular administration of low doses of neuropefitde y in mice

1996 • 22 citations

Dorsal column lesion prevents mechanical hyperalgesia and allodynia in osteotomy model

1999 • 22 citations

Dynamic and static components of mechanical hyperalgesia in human hairy skin

1993 • 19 citations

Light- and electron-microscopic analysis of neuropeptide Y-immunoreactive profiles in the cat spinal dorsal horn

1994 • 18 citations

The Egg Cortex in Early Development of Sea Urchins and Starfish

1986 • 17 citations

Partial sciatic nerve ligation induced more dramatic increase of neuropeptide Y immunoreactive axonal fibers in the gracile nucleus of middle‐aged rats than in young adult rats

2000 • 1 citations