Osmotic stress causes a G₁ cell cycle delay and downregulation of Cln3/Cdc28 activity in Saccharomyces cerevisiae

Current protocols in molecular biology

1988 • 7,584 citations

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae

1994 • 2,554 citations

An Osmosensing Signal Transduction Pathway in Yeast

1993 • 1,252 citations

The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE).

1996 • 1,050 citations

MAP Kinase Pathways in the Yeast Saccharomyces cerevisiae

1998 • 939 citations

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1994 • 902 citations

Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity

1998 • 759 citations

Activation of Yeast PBS2 MAPKK by MAPKKKs or by Binding of an SH3-Containing Osmosensor

1995 • 649 citations

A Set of Vectors with a Tetracycline-Regulatable Promoter System for Modulated Gene Expression inSaccharomyces cerevisiae

1997 • 603 citations

Yeast Stress Responses

2002 • 592 citations

Osmotic Activation of the HOG MAPK Pathway via Ste11p MAPKKK: Scaffold Role of Pbs2p MAPKK

1997 • 569 citations

The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog.

1988 • 563 citations

CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

1993 • 521 citations

Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins.

1993 • 492 citations

Control of Cyclin D1, p27^Kip1, and Cell Cycle Progression in Human Capillary Endothelial Cells by Cell Shape and Cytoskeletal Tension

1998 • 476 citations

Msn2p, a zinc finger DNA-binding protein, is the transcriptional activator of the multistress response in Saccharomyces cerevisiae.

1996 • 476 citations

DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae.

1988 • 445 citations

Regulation of Cdc28 Cyclin-Dependent Protein Kinase Activity during the Cell Cycle of the Yeast Saccharomyces cerevisiae

1998 • 421 citations

Stress signaling in yeast

1995 • 415 citations

The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation.

1992 • 414 citations

Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1

1998 • 414 citations

CLB5: a novel B cyclin from budding yeast with a role in S phase.

1992 • 391 citations

The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae

1998 • 386 citations

Salt Tolerance in Plants and Microorganisms: Toxicity Targets and Defense Responses

1996 • 352 citations

Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae.

1995 • 337 citations

Nim1-related kinases coordinate cell cycle progression with the organization of the peripheral cytoskeleton in yeast

1999 • 308 citations

Signalling in the Yeasts: An Informational Cascade with Links to the Filamentous Fungi

1998 • 298 citations

p34^Cdc28-Mediated Control of Cln3 Cyclin Degradation

1995 • 293 citations

Coupling of cell division to cell growth by translational control of the G₁ cyclin CLN3 in yeast

1997 • 290 citations

Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator

1998 • 289 citations

A cell cycle checkpoint monitors cell morphogenesis in budding yeast.

1995 • 267 citations

Direct Inhibition of the Yeast Cyclin-Dependent Kinase Cdc28-Cln by Far1

1994 • 258 citations

Osmotic stress and the yeast cytoskeleton: phenotype-specific suppression of an actin mutation.

1992 • 245 citations

An Inhibitor of p34 ^CDC28 Protein Kinase Activity from Saccharomyces cerevisiae

1993 • 236 citations

Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1.

1996 • 227 citations

The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex.

1989 • 206 citations

A novel Mcm1-dependent element in the SWI4, CLN3, CDC6, and CDC47 promoters activates M/G1-specific transcription.

1997 • 206 citations

CLN3, not positive feedback, determines the timing of CLN2 transcription in cycling cells.

1995 • 187 citations

CLB5-Dependent Activation of Late Replication Origins in S. cerevisiae

1998 • 176 citations

The Cln3 cyclin is down-regulated by translational repression and degradation during the G1 arrest caused by nitrogen deprivation in budding yeast

1997 • 175 citations

Far1 and Fus3 link the mating pheromone signal transduction pathway to three G1-phase Cdc28 kinase complexes.

1993 • 174 citations

Yeast G1 cyclins CLN1 and CLN2 and a GAP-like protein have a role in bud formation.

1993 • 172 citations

Rck2 Kinase Is a Substrate for the Osmotic Stress-Activated Mitogen-Activated Protein Kinase Hog1

2000 • 150 citations

Cdc28 tyrosine phosphorylation and the morphogenesis checkpoint in budding yeast.

1996 • 146 citations

Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins.

1995 • 134 citations

Response of Saccharomyces cerevisiae to severe osmotic stress: evidence for a novel activation mechanism of the HOG MAP kinase pathway

2000 • 122 citations

Cell Death Studies Yield Cancer Clues

1993 • 120 citations

Heat Shock-Mediated Cell Cycle Blockage and G1 Cyclin Expression in the Yeast Saccharomyces cerevisiae

1993 • 119 citations

Regulation of the Cln3-Cdc28 kinase by cAMP in Saccharomyces cerevisiae

1998 • 119 citations

Osmostress‐induced changes in yeast gene expression

1992 • 115 citations

The B-type cyclin kinase inhibitor p40(SiC1) Controls the G1 to S transition in S-cerevisiae (vol 79, pg 233, 1994)

1996 • 111 citations

Xbp1, a Stress-Induced Transcriptional Repressor of the Saccharomyces cerevisiae Swi4/Mbp1 Family

1997 • 107 citations

Positioning of cell growth and division after osmotic stress requires a map kinase pathway

1994 • 100 citations

The Cdk-associated protein Cks1 functions both in G1 and G2 in Saccharomyces cerevisiae.

1993 • 99 citations

The Osmoregulatory Pathway Represses Mating Pathway Activity in Saccharomyces cerevisiae: Isolation of a FUS3 Mutant That Is Insensitive to the Repression Mechanism

1996 • 99 citations

Pheromone-Dependent G₁ Cell Cycle Arrest Requires Far1 Phosphorylation, but May Not Involve Inhibition of Cdc28-Cln2 Kinase, In Vivo

1998 • 92 citations

Heat shock-mediated cell cycle blockage and G1 cyclin expression in the yeast Saccharomyces cerevisiae.

1993 • 92 citations

The yeast Cln3 protein is an unstable activator of Cdc28.

1993 • 90 citations

Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets

1999 • 82 citations

Activation of the Saccharomyces cerevisiae Filamentation/Invasion Pathway by Osmotic Stress in High-Osmolarity Glycogen Pathway Mutants

1999 • 80 citations

The Molecular Chaperone Ydj1 Is Required for the p34^CDC28-Dependent Phosphorylation of the Cyclin Cln3 That Signals Its Degradation

1996 • 71 citations

Phosphorylation-Independent Inhibition of Cdc28p by the Tyrosine Kinase Swe1p in the Morphogenesis Checkpoint

1999 • 68 citations

General stress response: In search of a common denominator.

1997 • 67 citations

Cks1 Is Required for G₁Cyclin–Cyclin-Dependent Kinase Activity in Budding Yeast

2000 • 65 citations

Transcriptional Remodeling and G1 Arrest in Dioxygen Stress in Saccharomyces cerevisiae

1996 • 56 citations

Growth-Independent Regulation of CLN3 mRNA Levels by Nutrients in Saccharomyces cerevisiae

1998 • 53 citations

Cln3-Associated Kinase Activity in Saccharomyces cerevisiae Is Regulated by the Mating Factor Pathway

1998 • 49 citations

Clb5-associated Kinase Activity is Required Early in the Spindle Pathway for Correct Preanaphase Nuclear Positioning in Saccharomyces cerevisiae

1998 • 48 citations

Small Heat Shock Protein Suppression of Vpr-Induced Cytoskeletal Defects in Budding Yeast

1997 • 37 citations

In budding yeast, reactive oxygen species induce both RAS‐dependent and RAS‐independent cell cycle‐specific arrest

1999 • 25 citations

Heat‐induced cell cycle arrest of Saccharomyces cerevisiae : involvement of the RAD6/UBC2 and WSC2 genes in its reversal

1999 • 19 citations