The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells.

Prevalence of Human Papillomavirus in Cervical Cancer: a Worldwide Perspective

1995 • 3,371 citations

Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers

2000 • 3,004 citations

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3

2000 • 1,073 citations

Increasing complexity of Ras signaling

1998 • 1,069 citations

Epigenetic Inactivation of RASSF1A in Lung and Breast Cancers and Malignant Phenotype Suppression

2001 • 770 citations

The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.

2000 • 534 citations

Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features.

2001 • 419 citations

Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours

2001 • 379 citations

The candidate tumor suppressor gene, RASSF1A , from human chromosome 3p21.3 is involved in kidney tumorigenesis

2001 • 296 citations

Ras Uses the Novel Tumor Suppressor RASSF1 as an Effector to Mediate Apoptosis

2000 • 295 citations

High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma.

2001 • 290 citations

Epigenetic inactivation of the RASSF1A 3p21.3 tumor suppressor gene in both clear cell and papillary renal cell carcinoma.

2001 • 200 citations

Generation and genetic characterization of immortal human prostate epithelial cell lines derived from primary cancer specimens.

1997 • 138 citations

Frequent epigenetic inactivation of RASSF1A in human bladder carcinoma.

2001 • 138 citations

RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours

2001 • 137 citations

Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma.

2001 • 135 citations

Stepwise immortalization and transformation of adult human prostate epithelial cells by a combination of HPV-18 and v-Ki-ras.

1994 • 96 citations

Widely used prostate carcinoma cell lines share common origins

2001 • 82 citations

Human cell lines engineered for tetracycline‐regulated expression of tumor suppressor candidate genes from a frequently affected chromosomal region, 3p21

2002 • 59 citations

Human papillomavirus and urological tumours: II. Role in bladder, prostate, renal and testicular cancer

2000 • 34 citations

A novel human cancer culture model for the study of prostate cancer

2001 • 34 citations

Malignant transformation of human prostate epithelial cells by N-nitroso-N-methylurea.

1997 • 27 citations