A mechanism of protein localization: the signal hypothesis and bacteria.

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Functions of Lysosomes

1966 • 2,942 citations

Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu

1976 • 1,895 citations

Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.

1978 • 791 citations

The Outer Membrane of Gram-negative Bacteria

1980 • 588 citations

The Outer Membrane Proteins of Gram-Negative Bacteria: Biosynthesis, Assembly, and Functions

1978 • 457 citations

Isolation of the Bacteriophage Lambda Receptor from Escherichia coli

1973 • 433 citations

Maltose Transport in Escherichia coli K12. A Comparison of Transport Kinetics in Wild-Type and lamba-Resistant Mutants with the Dissociation Constants of the Maltose-Binding Protein as Measured by Fluorescence Quenching

1976 • 313 citations

Amino acid sequence for the peptide extension on the prolipoprotein of the Escherichia coli outer membrane.

1977 • 286 citations

The mechanism of protein secretion across membranes

1980 • 285 citations

Mutations which alter the function of the signal sequence of the maltose binding protein of Escherichia coli

1980 • 268 citations

Use of gene fusion to study secretion of maltose-binding protein into Escherichia coli periplasm

1979 • 267 citations

Bacterial outer membranes: Biogenesis and functions

1979 • 254 citations

Active Transport of Maltose in Escherichia coli K12

1974 • 251 citations

Sequence analysis of mutations that prevent export of λ receptor, an Escherichia coli outer membrane protein

1980 • 195 citations

Translocation of proteins across membranes: the signal hypothesis and beyond.

1979 • 176 citations

Dominant constitutive mutations in malT, the positive regulator gene of the maltose regulon in Escherichia coli

1978 • 165 citations

Export without proteolytic processing of inner and outer membrane proteins encoded by F sex factor tra cistrons in Escherichia coli minicells.

1979 • 162 citations

Use of gene fusions to study outer membrane protein localization in Escherichia coli.

1977 • 148 citations

Studies on bacteriophage fd DNA

1977 • 147 citations

Labeling of proteins with beta-galactosidase by gene fusion. Identification of a cytoplasmic membrane component of the Escherichia coli maltose transport system.

1980 • 145 citations

Structure of the malB region in Escherichia coli K12

1979 • 144 citations

Outer membrane of gram-negative bacteria. XVIII. Electron microscopic studies on porin insertion sites and growth of cell surface of Salmonella typhimurium

1978 • 143 citations

DIVERGENT OPERONS AND THE GENETIC STRUCTURE OF THE MALTOSE B REGION IN ESCHERICHIA COLI K12

1974 • 130 citations

Escherichia coli mutants accumulating the precursor of a secreted protein in the cytoplasm

1979 • 129 citations

Extracellular labeling of nascent polypeptides traversing the membrane of Escherichia coli.

1977 • 128 citations

Precursors of three exported proteins in Escherichia coli.

1978 • 123 citations

Escherichia coli pleiotropic mutant that reduces amounts of several periplasmic and outer membrane proteins

1979 • 118 citations

Mutations altering the cellular localization of the phage lambda receptor, an Escherichia coli outer membrane protein.

1978 • 106 citations

Membrane biogenesis: cotranslational integration of the bacteriophage f1 coat protein into an Escherichia coli membrane fraction.

1979 • 103 citations

Intergration of the receptor for bacteriophage lambda in the outer membrane of Escherichia coli: coupling with cell division

1975 • 99 citations

The Assembly of Cell Membranes

1979 • 95 citations

Functional Specialization of Membrane-Bound Ribosomes in Eukaryotic Cells

1976 • 61 citations

DNA sequence encoding the NH2-terminal peptide involved in transport of lambda receptor, an Escherichia coli secretory protein.

1980 • 52 citations

Use of gene fusions to determine a partial signal sequence of alkaline phosphatase

1979 • 41 citations

Sequence and Regulatory Signals of the Filamentous Phage Genome

1978 • 29 citations