Reversible cellular adhesion to vitronectin linked to urokinase receptor occupancy.

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Protein Purification: Principles and Practice

1982 • 1,029 citations

Cell-Associated Plasminogen Activation: Regulation and Physiological Functions

1988 • 826 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase.

1985 • 731 citations

Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors

1987 • 625 citations

Novel purification of vitronectin from human plasma by heparin affinity chromatography.

1988 • 525 citations

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes.

1990 • 480 citations

Structure and Biological Role of Vitronectin

1991 • 477 citations

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes.

1985 • 450 citations

Prevention of metastasis by inhibition of the urokinase receptor.

1993 • 387 citations

Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1.

1990 • 374 citations

Autocrine saturation of pro-urokinase receptors on human A431 cells

1986 • 361 citations

A 55,000-60,000 Mr receptor protein for urokinase-type plasminogen activator. Identification in human tumor cell lines and partial purification.

1988 • 275 citations

Inhibition of receptor-bound urokinase by plasminogen-activator inhibitors.

1990 • 272 citations

A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin.

1993 • 264 citations

Structural requirements for the growth factor activity of the amino-terminal domain of urokinase.

1992 • 236 citations

Macrophage fibrinolytic activity: Identification of two pathways of plasmin formation by intact cells and of a plasminogen activator inhibitor

1982 • 225 citations

Interaction of Plasminogen Activator Inhibitor (PAI-1) with Vitronectin

1989 • 191 citations

Internalization of the urokinase-plasminogen activator inhibitor type-1 complex is mediated by the urokinase receptor.

1992 • 184 citations

Accessibility of receptor-bound urokinase to type-1 plasminogen activator inhibitor.

1989 • 182 citations

Cytokines induce urokinase-dependent adhesion of human myeloid cells. A regulatory role for plasminogen activator inhibitors.

1993 • 138 citations

An autocrine role for urokinase in phorbol ester-mediated differentiation of myeloid cell lines.

1991 • 137 citations

Single chain urokinase. Augmentation of enzymatic activity upon binding to monocytes

1991 • 110 citations

Functional characteristics of receptor-bound urokinase on human monocytes: catalytic efficiency and susceptibility to inactivation by plasminogen activator inhibitors

1989 • 99 citations

Endogenous receptor-bound urokinase mediates tissue invasion of human monocytes.

1989 • 96 citations

Alteration of vitronectin. Characterization of changes induced by treatment with urea.

1993 • 70 citations

Protein Purification: Principles and Practice

1984 • 66 citations

Binding of vitronectin-thrombin-antithrombin III complex to human endothelial cells is mediated by the heparin binding site of vitronectin.

1992 • 63 citations

Receptor-mediated endocytosis of vitronectin is regulated by its conformational state

1993 • 57 citations

Developmental expression of plasminogen activator inhibitor type 1 by human alveolar macrophages. Possible role in lung injury.

1990 • 55 citations

Lipopolysaccharide-induced modulation of human monocyte urokinase production and activity.

1990 • 36 citations