Role of Escherichia coli heat shock proteins DnaK and HtpG (C62.5) in response to nutritional deprivation

Experiments in molecular genetics

1972 • 28,260 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

Culture Medium for Enterobacteria

1974 • 3,002 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

Homologous plant and bacterial proteins chaperone oligomeric protein assembly

1988 • 1,316 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

The Heat Shock Respons

1985 • 809 citations

THE GENETICS AND REGULATION OF HEAT-SHOCK PROTEINS

1984 • 648 citations

hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures.

1989 • 624 citations

The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels

1982 • 542 citations

Major heat shock gene of Drosophila and the Escherichia coli heat-inducible dnaK gene are homologous.

1984 • 513 citations

Molecular chaperones: proteins essential for the biogenesis of some macromolecular structures

1989 • 491 citations

The E. coli dnaK gene product, the hsp70 homolog, can reactivate heat-inactivated RNA polymerase in an ATP hydrolysis-dependent manner

1990 • 407 citations

Accumulation of a specific subset of D. melanogaster heat shock mRNAs in normal development without heat shock

1983 • 365 citations

Characterization of the yeast HSP60 gene coding for a mitochondrial assembly factor

1989 • 335 citations

The dnaK protein modulates the heat-shock response of Escherichia coli

1983 • 328 citations

An Ancient Developmental Induction: Heat-Shock Proteins Induced in Sporulation and Oogenesis

1986 • 294 citations

Mutations in the gene coding for Escherichia coli DNA topoisomerase I affect transcription and transposition.

1981 • 284 citations

Starvation proteins in Escherichia coli: kinetics of synthesis and role in starvation survival

1986 • 268 citations

Sigma 32 synthesis can regulate the synthesis of heat shock proteins in Escherichia coli.

1987 • 249 citations

A Highly Evolutionarily Conserved Mitochondrial Protein Is Structurally Related to the Protein Encoded by the Escherichia coli groEL Gene

1988 • 247 citations

hsp82 Is an Essential Protein That Is Required in Higher Concentrations for Growth of Cells at Higher Temperatures

1989 • 244 citations

Cellular defects caused by deletion of the Escherichia coli dnaK gene indicate roles for heat shock protein in normal metabolism

1989 • 234 citations

Escherichia coli dnaK null mutants are inviable at high temperature

1987 • 231 citations

Eukaryotic Mr 83,000 heat shock protein has a homologue in Escherichia coli.

1987 • 211 citations

Escherichia coli heat shock gene mutants are defective in proteolysis.

1988 • 205 citations

Modulation of gene expression by drugs affecting deoxyribonucleic acid gyrase

1979 • 197 citations

Role of the Escherichia coli DnaK and DnaJ heat shock proteins in the initiation of bacteriophage lambda DNA replication.

1988 • 194 citations

Heat-shock proteins DnaK and GroEL facilitate export of LacZ hybrid proteins in E. coli

1990 • 175 citations

Ancient heat shock gene is dispensable

1988 • 173 citations

Modulation of stability of the Escherichia coli heat shock regulatory factor sigma

1989 • 169 citations

A highly evolutionarily conserved mitochondrial protein is structurally related to the protein encoded by the Escherichia coli groEL gene.

1988 • 163 citations

A new bacterial gene (groPC) which affects λ DNA replication

1977 • 156 citations

Genetic analysis of two genes, dnaJ and dnaK, necessary for Escherichia coli and bacteriophage lambda DNA replication

1978 • 144 citations

The Role of Cyclic AMP in Bacteria

1971 • 141 citations

Differential regulation by cyclic AMP of starvation protein synthesis in Escherichia coli

1988 • 118 citations

Overlapping and separate controls on the phosphate regulon in Escherichia coli K12

1983 • 68 citations

Aging results in an unusual expression of Drosophila heat shock proteins.

1988 • 62 citations

The B66.0 protein of Escherichia coli is the product of the dnaK+ gene

1982 • 62 citations

Antibody to sigma 32 cross-reacts with DnaK: association of DnaK protein with Escherichia coli RNA polymerase.

1988 • 23 citations

An RNA Polymerase Mutant Defective in ATP Initiations

1970 • 15 citations

The Escherichia coli dnaJ mutation affects biosynthesis of specific proteins, including those of the lac operon

1987 • 13 citations