Disruption of intracellular processing of epidermal growth factor by methylamine inhibits epidermal growth factor-induced DNA synthesis but not early morphological or transcriptional events.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Epidermal Growth Factor and a New Derivative

1972 • 1,225 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

1980 • 798 citations

Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts

1983 • 721 citations

Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells

1978 • 647 citations

Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431.

1978 • 578 citations

A common sequence of calcium and pH signals in the mitogenic stimulation of eukaryotic cells

1985 • 456 citations

Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts

1975 • 432 citations

Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts.

1985 • 344 citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

1986 • 339 citations

Acidification of macrophage and fibroblast endocytic vesicles in vitro.

1983 • 331 citations

Role of a Na+-dependent Cl-/HCO3- exchange in regulation of intracellular pH in fibroblasts.

1985 • 175 citations

Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line.

1983 • 155 citations

Characterization by electrophoresis of epidermal growth factor stimulated phosphorylation using A-431 membranes

1980 • 153 citations

Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells.

1983 • 150 citations

State of the viral DNA in rat cells transformed by polyoma virus. I. Virus rescue and the presence of nonintergrated viral DNA molecules

1976 • 127 citations

Further purification of epidermal growth factor by high-performance liquid chromatography

1982 • 103 citations

Human lysosomes can be purified from diploid skin fibroblasts by free-flow electrophoresis.

1980 • 84 citations

Inhibitors of 125I-epidermal growth factor internalization

1980 • 74 citations

Lysosomotropic amines inhibit mitogenesis induced by growth factors.

1981 • 73 citations

Evaluation of S phase synchronization by analysis of DNA replication in 5-bromodeoxyuridine

1973 • 68 citations

Intracellular processing of epidermal growth factor. I. Acidification of 125I-epidermal growth factor in intracellular organelles.

1984 • 54 citations

Intracellular processing of epidermal growth factor. II. Intracellular cleavage of the COOH-terminal region of 125I-epidermal growth factor.

1984 • 49 citations

Exposure of cells to an acidic environment reverses the inhibiton by methylamine of the mitogenic response to epidermal growth factor

1982 • 26 citations

Effect of methylamine on internalization, processing and biological activation of epidermal growth factor receptor

1980 • 26 citations

Mechanism of synergistic induction of DNA synthesis by epidermal growth factor and tumor promoters

1981 • 23 citations

Binding, internalization and intracellular processing of 125I-epidermal growth factor purified by isoelectric focusing

1982 • 19 citations

Intracellular processing of ¹²⁵I‐epidermal growth factor in rat embryo fibroblasts

1982 • 16 citations

Differential effects of lysosomotropic amines and polyamines on processing and biological activity of EGF

1984 • 10 citations