Peptide intermediates in the degradation of cellular proteins. Bestatin permits their accumulation in mouse liver in vivo.

Functions of Lysosomes

1966 • 2,942 citations

Lysosomes in biology and pathology

1977 • 2,068 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells

1974 • 1,775 citations

Endocytosis

1977 • 1,275 citations

The Role of Surface Carbohydrates in the Hepatic Recognition and Transport of Circulating Glycoproteins

1974 • 1,200 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells: Part 2

1976 • 1,060 citations

Proteinases in mammalian cells and tissues

1978 • 981 citations

Lysosomes and storage diseases

1973 • 745 citations

The biochemistry of glycoproteins and proteoglycans

1980 • 651 citations

Mechanisms of Intracellular Protein Breakdown

1982 • 647 citations

PROTEIN DEGRADATION IN CULTURED CELLS

1974 • 603 citations

A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes.

1977 • 553 citations

PROCESSING MECHANISMS IN THE BIOSYNTHESIS OF PROTEINS*

1980 • 461 citations

GASOMETRIC DETERMINATION OF CARBOXYL GROUPS IN FREE AMINO ACIDS

1941 • 457 citations

Protein Turnover and Lysosome Function

1978 • 279 citations

Inhibition by insulin of the formation of autophagic vacuoles in rat liver. A morphometric approach to the kinetics of intracellular degradation by autophagy.

1978 • 276 citations

Inhibition of glycosidases by aldonolactones of corresponding configuration. 2. Inhibitors of β-N-acetylglucosaminidase

1958 • 251 citations

Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells

1976 • 234 citations

Quantitative relationship between autophagy and proteolysis during graded amino acid deprivation in perfused rat liver.

1981 • 223 citations

Direct evidence of importance of lysosomes in degradation of intracellular proteins

1975 • 209 citations

Protein Degradation in Cultured Cells

1973 • 195 citations

Autophagy, heterophagy, microautophagy and crinophagy as the means for intracellular degradation

1981 • 177 citations

Role of changes in protein degradation in the growth of regenerating livers.

1976 • 150 citations

Isolation of autophagic vacuoles from rat liver: morphological and biochemical characterization.

1982 • 150 citations

In Vivo Rate of Translation by Ribosomes of Normal and Regenerating Liver

1974 • 135 citations

THE FATE OF PEPTIDES PINOCYTOSED BY MACROPHAGES IN VITRO

1969 • 127 citations

General characteristics of protein degradation in diabetes and starvation.

1978 • 125 citations

The selective degradation of injected proteins occurs principally in the cytosol rather than in lysosomes

1981 • 103 citations

Evidence for the autophagy of microinjected proteins in HeLA cells.

1977 • 95 citations

A study of permeability of lysosomes to amino acids and small peptides

1971 • 66 citations

Evidence for degradation of myofibrillar proteins in lysosomes. Myofibrillar proteins derivatized by intramuscular injection of N-ethylmaleimide are sequestered in lysosomes.

1979 • 37 citations

Isolation and Characterization of Autolysosomes which Appeared in Rat Liver after Leupeptin Treatment

1982 • 34 citations

Degradation of abnormal proteins in intact mouse reticulocytes: accumulation of intermediates in the presence of bestatin.

1979 • 33 citations

Intermediates in the degradation of abnormal globin. Bestatin permits the accumulation of the same peptides in cell-free extracts as in intact reticulocytes.

1979 • 32 citations

Characterization of chloroquine-induced autophagic vacuoles isolated from rat liver

1981 • 27 citations

PROTEASE ACTIVITIES PRESENT IN DOG PANCREATIC MEMBRANES THAT PROCESS HUMAN PRE‐PLACENTAL LACTOGEN

1980 • 24 citations