A subset of human CD34+ hematopoietic progenitors express low levels of CD4, the high-affinity receptor for human immunodeficiency virus-type 1

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

Establishment and characterization of a unique human cell line that proliferates dependently on GM‐CSF, IL‐3, or erythropoietin

1989 • 833 citations

T Cell Subsets and the Recognition of MHC Class

1983 • 702 citations

Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis.

1992 • 689 citations

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family

1985 • 669 citations

Molecular Biology and Function of CD4 and CD8

1989 • 388 citations

Infection and Replication of HIV-1 in Purified Progenitor Cells of Normal Human Bone Marrow

1988 • 375 citations

Perturbation of the T4 molecule transmits a negative signal to T cells.

1985 • 335 citations

T Cell Activation Antigen, CD26, as a Cofactor for Entry of HIV in CD4 ⁺ Cells

1993 • 217 citations

CD34+ bone marrow cells are infected with HIV in a subset of seropositive individuals.

1992 • 173 citations

Pathophysiology and management of HIV-associated hematologic disorders

1989 • 164 citations

Quantitative Immunocytofluorographic Analysis of CD4 Surface Antigen Expression and HIV Infection of Human Peripheral Blood Monocyte/Macrophages

1987 • 153 citations

Differences in CD4 dependence for infectivity of laboratory-adapted and primary patient isolates of human immunodeficiency virus type 1

1994 • 148 citations

CD34+ hematopoietic progenitor cells are not a major reservoir of the human immunodeficiency virus

1990 • 144 citations

In vitro suppression of normal human bone marrow progenitor cells by human immunodeficiency virus

1991 • 133 citations

Human eosinophils express CD4 protein and bind human immunodeficiency virus 1 gp120.

1989 • 133 citations

The Block to HIV-1 Envelope Glycoprotein-Mediated Membrane Fusion in Animal Cells Expressing Human CD4 Can Be Overcome by a Human Cell Component(s)

1993 • 124 citations

Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta + and TCR gamma delta + to human immunodeficiency virus infection: a mechanism for CD4+ (T4) lymphocyte depletion.

1990 • 124 citations

Lack of evidence for infection of or effect on growth of hematopoietic progenitor cells after in vivo or in vitro exposure to human immunodeficiency virus

1990 • 123 citations

Human T lymphocytes and monocytes bear the same Leu-3(T4) antigen.

1986 • 121 citations

Molecular Interactions, T‐Cell Subsets and a Role of the CD4/CD8:p56^lck Complex in Human T‐Cell Activation

1989 • 118 citations

Cofactor requirement for human immunodeficiency virus type 1 entry into a CD4-expressing human cell line

1993 • 107 citations

Role of human immunodeficiency virus replication in defective in vitro growth of hematopoietic progenitors

1992 • 95 citations

Macrophage-active colony-stimulating factors enhance human immunodeficiency virus type 1 infection in bone marrow stem cells [see comments]

1991 • 87 citations

CD4 is expressed on murine pluripotent hematopoietic stem cells

1992 • 81 citations

In vitro exposure to human immunodeficiency virus type 1 induces apoptotic cell death of the factor-dependent TF-1 hematopoietic cell line

1994 • 74 citations

Sequential loss of CD34 and class II MHC antigens on purified cord blood hematopoietic progenitors cultured with IL-3: characterization of CD34-, HLA-DR+ cells

1989 • 73 citations

Uninfected haematopoietic progenitor (CD34+) cells purified from the bone marrow of AIDS patients are committed to apoptotic cell death in culture

1993 • 63 citations

Detection of surface and cytoplasmic CD4 on blood monocytes from normal and HIV-1 infected individuals

1990 • 60 citations

Expression of CD4 by human megakaryocytes.

1990 • 59 citations

Human megakaryocytes have a CD4 molecule capable of binding human immunodeficiency virus-1

1993 • 59 citations

Presence and characteristics of circulating megakaryocyte progenitor cells in human fetal blood

1993 • 32 citations

Role of HIV infection in the hematologic manifestations of HIV seropositive subjects

1993 • 23 citations

The CD4 molecule belongs to the phenotypic repertoire of most cases of acute myeloid leukemia.

1992 • 14 citations