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Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity

1984 • 1,746 citations

THE ROLE OF ENDOTHELIAL CELLS IN INFLAMMATION

1990 • 808 citations

Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase.

1986 • 576 citations

Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process

1990 • 563 citations

Elastase in Tissue Injury

1985 • 512 citations

Neutrophil-mediated mucosal injury

1988 • 445 citations

Toward an Epidemiology of Gastropathy Associated With Nonsteroidal Antiinflammatory Drug Use

1989 • 392 citations

ONO-5046, a novel inhibitor of human neutrophil elastase

1991 • 359 citations

Proteolysis by Neutrophils

1982 • 244 citations

Indomethacin-induced leukocyte adhesion in mesenteric venules: role of lipoxygenase products

1992 • 206 citations

Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumour necrosis factor alpha.

1994 • 192 citations

Gastroscopy is incomplete without biopsy: Clinical relevance of distinguishing gastropathy from gastritis

1995 • 161 citations

Gastric mucosal protection by OPC-12759, a novel antiulcer compound, in the rat

1987 • 144 citations

Reperfusion-induced leukocyte infiltration: role of elastase

1990 • 137 citations

Stimulation of prostaglandin biosynthesis mediates gastroprotective effect of rebamipide in rats

1993 • 132 citations

Levofloxacin, a new quinolone antibacterial agent. An introductory overview.

1992 • 120 citations

Antiulcer mechanism of action of rebamipide, a novel antiulcer compound, on diethyldithiocarbamate-induced antral gastric ulcers in rats

1992 • 96 citations

An oxygen-dependent mechanism of neutrophil-mediated cytotoxicity

1980 • 95 citations

Granulocyte proteases and hydrogen peroxide synergistically inactivate thrombomodulin of endothelial cells in vitro.

1994 • 88 citations

Prostacyclin and beraprost sodium as suppressors of activated rat polymorphonuclear leukocytes

1990 • 84 citations

Iloprost Inhibits Neutrophil-induced Lung Injury and Neutrophil Adherence to Endothelial Monolayers

1990 • 84 citations

Effect of OPC-12759, a novel antiulcer agent, on chronic and acute experimental gastric ulcer, and gastric secretion in rats.

1989 • 82 citations

Rebamipide, novel prostaglandin-inducer, accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer comparison with cimetidine

1995 • 65 citations

Effect of rebamipide on mucus secretion by endogenous prostaglandin-independent mechanism in rat gastric mucosa.

1992 • 65 citations

Endotoxin-induced pulmonary vascular injury is mainly mediated by activated neutrophils in rats

1995 • 64 citations

Non-Steroidal Anti-Inflammatory Drug Gastropathy and Cytoprotection: Pathogenesis and Mechanisms Re-examined

1992 • 63 citations

Effect of rebamipide on lipid peroxidation and gastric mucosal injury induced by indometacin in rats.

1993 • 58 citations

Formation of isotonic Nycodenz gradients for cell separations

1982 • 43 citations

A sensitive and specific assay for granulocyte elastase in inflammatory tissue fluid using L-pyroglutamyl-L-prolyl-L-valine-p-nitroanilide

1990 • 35 citations

Role of granulocyte elastase in the formation of hemorrhagic shock-induced gastric mucosal lesions in the rat

1996 • 23 citations

Studies on 2(1H)-quinolinone derivatives as gastric antiulcer active agents. Synthesis and antiulcer activity of the metabolites of 2-(4-chlorobenzoylamino)-3-(2(1H)-quinolinon-4-yl)propionic acid.

1986 • 16 citations

Role of lipid peroxidation in protection of rats by rebamipide against gastric mucosal lesions induced by stress plus indomethacin

1994 • 6 citations