Measurement of Mutant Frequency to 6-Thioguanine Resistance in Circulating T-lymphocytes for Human Population Monitoring

Xeroderma pigmentosum. Cutaneous, ocular, and neurologic abnormalities in 830 published cases

1987 • 1,070 citations

Xeroderma Pigmentosum

1987 • 774 citations

Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo ageing and low dose X-irradiation

1986 • 548 citations

T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood.

1982 • 386 citations

Direct demonstration of the clonogenic potential of every human peripheral blood T cell. Clonal analysis of HLA-DR expression and cytolytic activity.

1983 • 351 citations

Psoriasis: a disease of abnormal Keratinocyte proliferation induced by T lymphocytes

1986 • 335 citations

Mortality and Cancer Incidence in 263 Patients With Ataxia-Telangiectasia<xref ref-type="fn" rid="FN1">2</xref>

1986 • 309 citations

The Salmonella typhimurium/mammalian microsomal assay

1986 • 286 citations

T-cell subpopulations in the blood and skin of patients with psoriasis

1984 • 227 citations

Enumeration of 6-thioguanine-resistant peripheral blood lymphocytes in man as a potential test for somatic cell mutations arising in vivo

1979 • 183 citations

The effect of donor age on spontaneous and induced micronuclei

1985 • 179 citations

Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans

1987 • 178 citations

Ataxia-telangiectasia: a cellular and molecular link between cancer, neuropathology and immune deficiency

1983 • 161 citations

In vivo somatic mutations in human lymphocytes frequently result from major gene alterations

1985 • 146 citations

Alterations of the hprt gene in human in vivo-derived 6-thioguanine-resistant T lymphocytes

1985 • 143 citations

A further assessment of factors influencing measurements of thioguanine-resistant mutant frequency in circulating T-lymphocytes

1988 • 142 citations

Mutation frequency in human lymphocytes increases with age

1984 • 138 citations

Somatic gene mutations in vivo as indicated by the 6-thioguanine-resistant T-lymphocytes in human blood

1985 • 134 citations

Chemical carcinogens a review and analysis of the literature of selected chemicals and the establishment of the Gene-Tox carcinogen data base

1987 • 134 citations

Measurement of spontaneous and X-irradiation-induced 6-thioguanine-resistant human blood lymphocytes using a T-cell cloning technique

1984 • 102 citations

Double-blind study on the effect of cigarette smoking on the chromosomes of human peripheral blood lymphocytes in vivo

1982 • 94 citations

Population and Biological Aspects of Human Mutation

1982 • 94 citations

Sister-chromatid exchange (SCE) report on control subjects in a study of occupationally exposed workers

1984 • 92 citations

Detection of somatic mutations in man: evaluation of the microtitre cloning assay for T-lymphocytes

1986 • 80 citations

Use of T-cell receptor gene probes to quantify the in vivo hprt mutations in human T-lymphocytes

1986 • 77 citations

In vivo mutant frequency rises among breast cancer patients after exposure to high doses of γ-radiation

1985 • 77 citations

Psoralens potentiate ultraviolet light-induced inhibition of epidermal growth factor binding.

1986 • 74 citations

Human lymphocytes resistant to 6-thioguanine increase with age

1982 • 73 citations

Increased frequency of lymphocyte micronuclei in workers producing reinforced polyester resin with low exposure to styrene.

1983 • 56 citations

Variation in sister-chromatid exchange among 106 members of the general U.K. population

1986 • 55 citations

Increased frequency of chromosome aberrations in workers exposed to styrene.

1979 • 50 citations

Methods for study of mutations and mutagenesis in human lymphocytes

1985 • 50 citations

Deficiency of cyclic AMP-dependent protein kinases in human psoriasis.

1986 • 49 citations

Analysis of chromosome aberrations in lymphocytes of long-term heavy smokers

1986 • 49 citations

Increased chromosomal instability in lymphocytes from elderly humans

1985 • 49 citations

Molecular basis of X-ray-induced mutation at the HPRT locus in human lumphocytes

1986 • 47 citations

Induction of chromosome aberrations by styrene and vinylacetate in cultured human lymphocytes: dependence on erythrocytes

1986 • 45 citations

Sister-chromatid exchange in childhood in relation to age and sex

1986 • 38 citations

Abnormal lymphocyte function following long-term PUVA therapy for psoriasis

1983 • 36 citations

Higher incidence of spontaneous sister-chromatid exchanges (SCEs) and X-ray-induced chromosome aberrations in peripheral blood lymphocytes during pregnancy

1986 • 34 citations

Low human exposure to styrene in relation to chromosome breaks, gaps and sister chromatid exchanges

2008 • 32 citations

Chromosome damage induced in human lymphocytes by 5-methoxypsoralen and 8-methoxypsoralen plus UV-A

1987 • 31 citations

6-Thioguanine Resistant Peripheral Blood Lymphocytes in Humans Following Psoralen, Long-Wave Ultraviolet Light (PUVA) Therapy

1979 • 31 citations

Studies of DNA and Chromosome Damage in Skin Fibroblasts and Blood Lymphocytes from Psoriasis Patients Treated with 8-Methoxypsoralen and UVA Irradiation

1983 • 20 citations

Effects of ultraviolet radiation and immunosuppressive therapy on mouse epidermal cell kinetics

1986 • 16 citations

Tumor-producing and skin-irritating activity of dithranol (anthralin) and its 10-acyl analogues in SENCAR mice

1986 • 12 citations

Decreased Cloning of Lymphocytes from Elderly Individuals

1984 • 11 citations