Novel variants in benzo(a)pyrene metabolism. Isolation by fluorescence-activated cell sorting.

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 1,691 citations

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture.

1970 • 1,464 citations

Arene Oxides: A New Aspect of Drug Metabolism

1974 • 1,043 citations

Some current perspectives on chemical carcinogenesis in humans and experimental animals: Presidential Address.

1978 • 938 citations

A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses

1975 • 788 citations

Fluorescence Activated Cell Sorting

1972 • 774 citations

Chemical Carcinogenesis

1975 • 741 citations

Two Types of Ribosome in Mouse–Hamster Hybrid Cells

1971 • 577 citations

Handbook of Experimental Immunology

1988 • 446 citations

The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states

1969 • 425 citations

Aryl hydrocarbon (benzo[a]pyrene) hydroxylase in microsomes from rat tissues: Differential inhibition and stimulation by benzoflavones and organic solvents

1971 • 374 citations

Biochemical Mechanisms of Drug Toxicity

1974 • 337 citations

Metabolic Activation of Drugs to Toxic Substances

1975 • 281 citations

Metabolic Interactions Among Environmental Chemicals and Drugs

1972 • 261 citations

A perspective on the role of chemically reactive metabolites of foreign compounds in toxicity—I correlation of changes in covalent binding of reactivity metabolites with changes in the incidence and severity of toxicity

1974 • 225 citations

HISTOCHEMICAL DEMONSTRATION OF REDUCED PYRIDINE NUCLEOTIDE DEPENDENT POLYCYCLIC HYDROCARBON METABOLIZING SYSTEMS

1962 • 210 citations

Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase.

1979 • 191 citations

Alpha-Naphthoflavone: An Inhibitor of Hydrocarbon Cytotoxicity and Microsomal Hydroxylase

1969 • 185 citations

High-pressure liquid chromatographic analysis of benzo(alpha)pyrene metabolism and covalent binding and the mechanism of action of 7,8-benzoflavone and 1,2-epoxy-3,3,3-trichloropropane.

1974 • 175 citations

Carcinogens, Enzyme Induction, and Gene Action

1967 • 172 citations

Expression of liver phenotypes in cultured mouse hepatoma cells: Synthesis and secretion of serum albumin

1973 • 171 citations

ENZYMATIC HYDROXYLATION OF BENZOPYRENE AND ITS RELATIONSHIP TO CYTOTOXICITY

1969 • 136 citations

A perspective on the role of chemically reactive metabolites of foreign compounds in toxicity—II. Alterations in the kinetics of covalent binding

1974 • 107 citations

Mechanisms of Chemical Carcinogenesis

1978 • 91 citations

AUTOMATED CELL SORTING WITH FLOW SYSTEMS

1978 • 68 citations

STUDIES ON THE MECHANISM OF ARYL HYDROCARBON HYDROXYLASE INDUCTION AND ITS ROLE IN CYTOTOXICITY AND TUMORIGENICITY

1971 • 62 citations

Benzpyrene Hydroxylase Induction by Polycyclic Hydrocarbons in Hamster Embryonic Cells Grown in vitro

1967 • 48 citations

Variation in aryl hydrocarbon (benzo(a)pyrene) hydroxylase activity in heteroploid and predominantly diploid rat liver cells in culture.

1976 • 26 citations

Aryl hydrocarbon (benzo(a)pyrene) hydroxylase induction in cells in culture

1979 • 18 citations

Cell sorter analysis of carcinogen metabolites in human tissues.

1979 • 8 citations

Automated single-cell analysis of aryl hydrocarbon hydroxylase in human lymphocytes

1977 • 7 citations

In Vitro Cellular Uptake of Benzo [a] pyrene Measured by a Microfluorometric Technique

1971 • 4 citations