The role of HLA-G in human pregnancy

Natural killer cells and pregnancy

2002 • 1,216 citations

Combinations of Maternal KIR and Fetal HLA-C Genes Influence the Risk of Preeclampsia and Reproductive Success

2004 • 1,082 citations

Some immunological and endocrinological problems raised by the evolution of viviparity in verte- brates

1953 • 838 citations

Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis

1997 • 691 citations

HLA‐G and immune tolerance in pregnancy

2005 • 517 citations

Cutting Edge: Soluble HLA-G1 Triggers CD95/CD95 Ligand-Mediated Apoptosis in Activated CD8+ Cells by Interacting with CD8

2000 • 465 citations

Protein Expression and Peptide Binding Suggest Unique and Interacting Functional Roles for HLA-E, F, and G in Maternal-Placental Immune Recognition

2003 • 376 citations

Soluble HLA‐A,‐B,‐C and ‐G molecules induce apoptosis in T and NK CD8⁺ cells and inhibit cytotoxic T cell activity through CD8 ligation

2002 • 352 citations

HLA-G2, -G3, and -G4 Isoforms Expressed as Nonmature Cell Surface Glycoproteins Inhibit NK and Antigen-Specific CTL Cytolysis

2001 • 328 citations

Soluble HLA-G protein secreted by allo-specific CD4⁺T cells suppresses the allo-proliferative response: A CD4⁺T cell regulatory mechanism

2001 • 316 citations

HLA-G1-expressing antigen-presenting cells induce immunosuppressive CD4⁺T cells

2004 • 314 citations

HLA-G-mediated inhibition of antigen-specific cytotoxic T lymphocytes

1999 • 313 citations

Tolerization of dendritic cells by HLA‐G

2005 • 307 citations

Human Leukocyte Antigen-G Expression After Heart Transplantation Is Associated With a Reduced Incidence of Rejection

2002 • 248 citations

Immunology of term and preterm labor.

2003 • 217 citations

Microchimerism

2004 • 213 citations

HLA‐G has a concentration‐dependent effect on the generation of an allo‐CTL response

2000 • 200 citations

Detection of soluble HLA‐G molecules in plasma and amniotic fluid

1999 • 186 citations

HLA-G and IL-10 in serum in relation to HLA-G genotype and polymorphisms

2004 • 186 citations

HLA-G1 protein expression is not essential for fetal survival

1998 • 181 citations

Soluble HLA-G circulates in maternal blood during pregnancy

2000 • 180 citations

Association between human leukocyte antigen‐G genotype and success of in vitro fertilization and pregnancy outcome

2004 • 174 citations

Embryonic soluble HLA-G as a marker of developmental potential in embryos

2004 • 164 citations

HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition

2001 • 159 citations

Soluble HLA-G influences the release of cytokines from allogeneic peripheral blood mononuclear cells in culture

2001 • 147 citations

Crystal structure of HLA-G: A nonclassical MHC class I molecule expressed at the fetal–maternal interface

2005 • 146 citations

HLA-G inhibits the functions of murine dendritic cells via the PIR-B immune inhibitory receptor

2002 • 141 citations

Secretion of pro-apoptotic intron 4-retaining soluble HLA-G1 by human villous trophoblast

2002 • 127 citations

Placental Cell Expression of HLA-G2 Isoforms Is Limited to the Invasive Trophoblast Phenotype

2003 • 120 citations

Membrane-bound HLA-G activates proliferation and interferon- production by uterine natural killer cells

2004 • 114 citations

Maturation of antigen-presenting cells is compromised in HLA-G transgenic mice

2001 • 109 citations

Secretion of human leukocyte antigen-G by human embryos is associated with a higher in vitro fertilization pregnancy rate

2005 • 108 citations

Identification of a novel MHC class I gene, Mamu-AG, expressed in the placenta of a primate with an inactivated G locus.

1997 • 99 citations

Low plasma HLA-G protein concentrations in early gestation indicate the development of preeclampsia later in pregnancy

2005 • 97 citations

HLA-G inhibits the transendothelial migration of human NK cells

2000 • 95 citations

Soluble HLA-G inhibits human dendritic cell-triggered allogeneic T-cell proliferation without altering dendritic differentiation and maturation processes

2003 • 83 citations

Differential actions of progesterone and cortisol on lymphocyte and monocyte interaction during lymphocyte activation — relevance to immunosuppression in pregnancy

1983 • 81 citations

Major histocompatibility complex class I genes in primates: co‐evolution with pathogens

1999 • 74 citations

Recombinant HLA-G5 and -G6 drive U937 myelomonocytic cell production of TGF-β1

2004 • 72 citations

Role of HLA-G versus HLA-E on NK function: HLA-G is able to inhibit NK cytolysis by itself

1999 • 67 citations

HLA-G EXPRESSION PROTECTS PORCINE ENDOTHELIAL CELLS AGAINST NATURAL KILLER CELL-MEDIATED XENOGENEIC CYTOTOXICITY1,2

1999 • 62 citations

Allelic diversity at the primateMhc-G locus: Exon 3 bears stop codons in allCercophitecinae sequences

1996 • 60 citations

Premenstrual and Menstrual Changes in the Macaque and Human Endometrium

2002 • 58 citations

Fetomaternal cell traffic, pregnancy-associated progenitor cells, and autoimmune disease

2004 • 40 citations

Induction of HLA-G-restricted human cytomegalovirus pp65 (UL83)-specific cytotoxic T lymphocytes in HLA-G transgenic mice

2003 • 39 citations

Evolution of a new nonclassical MHC class I locus in two Old World primate species

1999 • 34 citations

Baboon placentas express soluble and membrane-bound Paan-AG proteins encoded by alternatively spliced transcripts of the class Ib major histocompatibility complex gene, Paan-AG

2002 • 34 citations

Do Nonhuman Primates Comprise Appropriate Experimental Models for Studying the Function of Human Leukocyte Antigen-G?1

2002 • 14 citations

Potential regulatory sequences in the untranslated regions of the baboon MHC class Ib gene, Paan-AG, more closely resemble those in the human MHC class Ia genes than those in the class Ib gene, HLA-G

2004 • 11 citations

Nonhuman primate placental MHC expression: a model for exploring mechanisms of human Maternal-Fetal immune tolerance

2003 • 10 citations

HLA-G expression protects porcine endothelial cells from xenogeneic cytotoxicity mediated by human natural killer cells

1999 • 8 citations

Inflammatory cells and cytokine production

2006 • 4 citations