Isolation and Relationship of Human Hexosaminidases

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

The Thiobarbituric Acid Assay of Sialic Acids

1959 • 6,482 citations

Quantitive estimation of sialic acids

1957 • 2,782 citations

Polyacrylamide Gel Electrophoresis

1971 • 784 citations

[5] Molecular weight determination of glycoproteins by polyacrylamide gel electrophoresis in sodium dodecyl sulfate

1972 • 782 citations

Tay-Sachs Disease: Generalized Absence of a Beta-D- N -Acetylhexosaminidase Component

1969 • 707 citations

N-Acetyl-β-glucosaminidases in human spleen

1968 • 523 citations

A hypothesis for I-cell disease: Defective hydrolases that do not enter lysosomes

1972 • 446 citations

Physical Studies of Lysozyme

1962 • 377 citations

ENZYME ALTERATIONS AND LIPID STORAGE IN THREE VARIANTS OF TAY‐SACHS DISEASE

1971 • 292 citations

Variation of β‐N‐acetylhexosaminidase‐pattern in Tay‐Sachs disease

1969 • 258 citations

Sphingolipids, Sphingolipidoses and Allied Disorders

1972 • 158 citations

The demonstration of multiple heat stable forms of N-acetyl-β-glucosaminidase in normal human serum

1972 • 154 citations

Membrane Sialic Acid and the Mechanism of Insulin Action in Adipose Tissue Cells

1971 • 144 citations

Demonstration of an alteration of ganglioside metabolism in Tay-Sachs disease

1969 • 133 citations

SYNTHESIS OF GLYCOPROTEINS AND GANGLIO-SIDES IN DEVELOPING RAT BRAIN

1971 • 115 citations

Anreicherung und Charakterisierung zweier Formen der menschlichen N-Acetyl-β-D-hexosaminidase

1971 • 111 citations

Isolation of β-N-Acetylhexosaminidase, β-N-Acetylglucosaminidase, and β-N-Acetylgalactosaminidase from Calf Brain^*

1967 • 110 citations

Hexosaminidase-A and Hexosamini-dase-B: Studies in Tay-Sachs' and Sandhoff's Disease

1973 • 100 citations

Purification of Two β-N-Acetyl-d-glucosaminidases from Beef Spleen

1972 • 84 citations

STUDIES ON BRAIN LIPIDS IN TAY‐SACHS’DISEASE—I ISOLATION OF TWO SIALIC ACID‐FREE GLYCOLIPIDS*

1963 • 84 citations

Immunological properties of N-acetyl-β-<scp>d</scp>-glucosaminidase of normal human liver and of GM2-gangliosidosis liver

1973 • 69 citations

The hydrolysis of Tay‐Sachs ganglioside (TSG) by human N‐acetyl‐β‐D‐hexosaminidase A

1970 • 65 citations

Tay‐sachs disease and related disorders: Fractionation of brain N‐acetyl‐β‐hexosaminidase on DEAE‐cellulose

1970 • 63 citations

The metabolism of Tay-Sachs ganglioside: catabolic studies with lysosomal enzymes from normal and Tay-Sachs brain tissue

1972 • 56 citations

Studies on the substrate specificity of hexosaminidase A and B from liver

1972 • 50 citations

The Catabolism of Tay-Sachs Ganglioside in Rat Brain Lysosomes

1972 • 47 citations

The purification and properties of a mammalian neuraminidase (sialidase)

1973 • 37 citations

The preparation of trihexosyl ‐ and tetrahexosyl gangliosides specifically labeled in the n‐acetylgalactosaminyl moiety

1972 • 16 citations

SH groups masked by subunit interaction in glyceraldehyde-3-phosphate dehydrogenase

1973 • 13 citations

Lipidoses

1972 • 9 citations