Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral Tat protein and cellular transcription factor Sp1

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Trans -Activator Gene of Human T-Lymphotropic Virus Type III (HTLV-III)

1985 • 872 citations

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

1985 • 825 citations

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

1987 • 672 citations

Tat trans-activates the human immunodeficiency virus through a nascent RNA target

1989 • 644 citations

Activators and targets

1990 • 582 citations

HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation

1989 • 577 citations

A vector for expressing GAL4(1–147) fusions tn mammalian cells

1989 • 558 citations

HIV-1 tat trans-activation requires the loop sequence within tar

1988 • 551 citations

Trans -Acting Transcriptional Regulation of Human T-Cell Leukemia Virus Type III Long Terminal Repeat

1985 • 500 citations

Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes

1988 • 397 citations

Characterization of a Human TAR RNA-Binding Protein That Activates the HIV-1 LTR

1991 • 391 citations

Binding of general transcription factor TFIIB to an acidic activating region

1991 • 377 citations

Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeat.

1989 • 357 citations

Elevated levels of mRNA can account for the trans-activation of human immunodeficiency virus.

1986 • 303 citations

HIV-1 Tat protein trans-activates transcription in vitro

1990 • 277 citations

Human immunodeficiency virus type 1 LTR TATA and TAR region sequences required for transcriptional regulation.

1989 • 275 citations

Alternative Mechanisms for Activation of Human Immunodeficiency Virus Enhancer in T Cells

1988 • 265 citations

TAR-independent activation of the HIV-1 LTR: Evidence that Tat requires specific regions of the promoter

1990 • 253 citations

Trans-activation by HIV-1 Tat via a heterologous RNA binding protein

1990 • 236 citations

The HIV-1 Tat protein: An RNA sequence-specific processivity factor?

1990 • 220 citations

The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: implications for Tat function.

1991 • 217 citations

Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein

1990 • 192 citations

Role of SP1-binding domains in in vivo transcriptional regulation of the human immunodeficiency virus type 1 long terminal repeat

1989 • 188 citations

HIV TAR: An RNA enhancer?

1989 • 175 citations

Structural requirements for trans activation of human immunodeficiency virus type 1 long terminal repeat-directed gene expression by tat: importance of base pairing, loop sequence, and bulges in the tat-responsive sequence

1990 • 142 citations

tat regulates binding of the human immunodeficiency virus trans-activating region RNA loop-binding protein TRP-185.

1991 • 139 citations

An Epstein-Barr virus immediate-early gene product trans-activates gene expression from the human immunodeficiency virus long terminal repeat.

1988 • 137 citations

Sp1-dependent activation of a synthetic promoter by human immunodeficiency virus type 1 Tat protein.

1991 • 124 citations

Isolation of a cellular protein that binds to the human immunodeficiency virus Tat protein and can potentiate transactivation of the viral promoter.

1991 • 59 citations

HIV-1 Expression Is Posttranscriptionally Repressed inDrosophilaCells

1989 • 5 citations