Molecular cloning of a cDNA encoding the “61-kDa” calmodulin-stimulated cyclic nucleotide phosphodiesterase. Tissue-specific expression of structurally related isoforms.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Current protocols in molecular biology

1988 • 7,584 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Structural features in eukaryotic mRNAs that modulate the initiation of translation.

1991 • 1,849 citations

λ ZAP: a bacteriophage λ expression vector within vivoexcision properties

1988 • 1,394 citations

Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors

1990 • 860 citations

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

1987 • 699 citations

Suppression by glutamate of cGMP-activated conductance in retinal bipolar cells

1990 • 465 citations

Selective inhibition of cyclic nucleotide phosphodiesterases of human, bovine and rat aorta

1986 • 301 citations

Alpha 1-adrenergic and muscarinic cholinergic stimulation of phosphoinositide hydrolysis in adult rat cardiomyocytes.

1985 • 298 citations

Multiple molecular forms of cyclic nucleotide phosphodiesterase in cardiac and smooth muscle and in platelets

1986 • 249 citations

Molecular biology of α-adrenergic receptors: implications for receptor classification and for structure-function relationships

1991 • 191 citations

Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle

1984 • 138 citations

Action of the cardiac alpha 1-adrenergic receptor. Activation of cyclic AMP degradation.

1985 • 117 citations

Molecular cloning of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase cDNA. Identification and distribution of isozyme variants.

1991 • 111 citations

Distribution of components of the guanosine 3′,5′-phosphate system in rat caudate-putamen

1983 • 102 citations

Purification of two calcium/calmodulin-dependent forms of cyclic nucleotide phosphodiesterase by using conformation-specific monoclonal antibody chromatography

1982 • 102 citations

Differential localization of calmodulin-dependent enzymes in rat brain: evidence for selective expression of cyclic nucleotide phosphodiesterase in specific neurons.

1987 • 96 citations

Demonstration of bovine brain calmodulin-dependent cyclic nucleotide phosphodiesterase isozymes by monoclonal antibodies.

1984 • 95 citations

Cellular distribution of phosphodiesterase isoforms in rat cardiac tissue.

1991 • 90 citations

Evidence for domain organization within the 61-kDa calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine brain

1991 • 85 citations

Biochemical events associated with activation of smooth muscle contraction.

1988 • 83 citations

Molecular cloning of cDNA encoding a “63”-kDa calmodulin-stimulated phosphodiesterase from bovine brain.

1992 • 72 citations

Differential recognition of calmodulin-enzyme complexes by a conformation-specific anti-calmodulin monoclonal antibody.

1986 • 67 citations

Proteolytic activation of calmodulin-dependent cyclic nucleotide phosphodiesterase.

1985 • 64 citations

Purification and characterization of bovine lung calmodulin-dependent cyclic nucleotide phosphodiesterase. An enzyme containing calmodulin as a subunit.

1986 • 63 citations

Potentiation of the effects of sodium nitroprusside and of isoproterenol by selective phosphodiesterase inhibitors.

1983 • 61 citations

Angiotensin II decreases cGMP levels in neuronal cultures from rat brain

1991 • 58 citations

Role of cyclic nucleotide phosphodiesterase isozymes in intact canine trachealis.

1991 • 54 citations

Characterization of a calcium-calmodulin-stimulated cyclic GMP phosphodiesterase from bovine brain

1985 • 51 citations

Identification of the phosphodiesterase regulated by muscarinic cholinergic receptors of 1321N1 human astrocytoma cells.

1986 • 48 citations

Sequence comparison of the 63-, 61-, and 59-kDa calmodulin-dependent cyclic nucleotide phosphodiesterases

1991 • 45 citations

Electron microscopic immunocytochemical evidence that the calmodulin-dependent cyclic nucleotide phosphodiesterase is localized predominantly at postsynaptic sites in the rat brain

1991 • 38 citations

Induction of a calcium/calmodulin-dependent phosphodiesterase during phytohemagglutinin-stimulated lymphocyte mitogenesis.

1990 • 37 citations

Testis-specific calmodulin-dependent phosphodiesterase. A distinct high affinity cAMP isoenzyme immunologically related to brain calmodulin-dependent cGMP phosphodiesterase.

1988 • 37 citations

The involvement of a calmodulin‐dependent phosphodiesterase in the negative control of carbamylcholine on cyclic AMP levels in dog thyroid slices

1983 • 34 citations

Mechanism of calcium-dependent inactivation of a potassium current in Aplysia neuron R15: interaction between calcium and cyclic AMP

1988 • 31 citations

The Biosynthesis and Actions of Prostaglandins in the Renal Collecting Tubule and Thick Ascending Limb

1989 • 17 citations