Steroid binding properties of beef adrenal cortical cytochrome P-450 which catalyzes the conversion of cholesterol into pregnenolone.

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

1949 • 16,078 citations

Coupling of spin, substrate, and redox equilibriums in cytochrome P450

1976 • 424 citations

Drug interaction with hepatic microsomal cytochrome.

1966 • 335 citations

SPIN-STATE CHANGES IN CYTOCHROME P-450 _cam ON BINDING OF SPECIFIC SUBSTRATES

1970 • 266 citations

Camphor binding by Pseudomonas putida cytochrome P-450

1971 • 262 citations

Cytochrome P-450 from Bovine Adrenocortical Mitochondria: an Enzyme for the Side Chain Cleavage of Cholesterol

1973 • 155 citations

Direct Studies on the Electron Transfer Sequence in Xanthine Oxidase by Electron Paramagnetic Resonance Spectroscopy

1964 • 142 citations

20α, 22ξ-Dihydroxycholesterol, an Intermediate in the Biosynthesis of Pregnenolone (3β-Hydroxypregn-5-en-20-one) from Cholesterol

1962 • 118 citations

Separation of two forms of cytochrome P450 adrenal cortex mitochondria

1970 • 107 citations

The Transformation of 20α-Hydroxycholesterol to Isocaproic Acid and C21 Steroids

1961 • 100 citations

Fractional solubilization of haemoproteins and partial purification of carbon monoxide-binding cytochrome from liver microsomes

1963 • 90 citations

Temperature dependence of cholesterol binding to cytochrome P-450scc of the rat adrenal. Effect of adrenocorticotropic hormone and cycloheximide.

1976 • 89 citations

Purification of cytochrome P-450 from bovine adrenocortical mitochondria by an “Aniline-sepharose” and the properties

1975 • 78 citations

Purification and characterization of adrenal cortex mitochondrial cytochrome P-450 specific for cholesterol side chain cleavage activity.

1976 • 75 citations

Mass spectrometric study of the enzymatic conversion of cholesterol to (22R)-22-hydroxycholesterol, (20R,22R)-20,22-dihydroxycholesterol, and pregnenolone, and of (22R)-22-hydroxycholesterol to the lgycol and pregnenolone in bovine adrenocortical preparations. Mode of oxygen incorporation

1975 • 73 citations

Substrate-induced Changes in Visible Absorption and Electron Spin Resonance Properties of Adrenal Cortex Mitochondrial P450

1970 • 66 citations

Studies on P-450

1969 • 64 citations

Formation of a cytochrome P-450scc-adrenodoxin complex

1977 • 54 citations

Temperature Jump Studies of Sperm Whale Metmyoglobin

1965 • 50 citations

Electron paramagnetic resonance and temperature dependent spin state studies of ferric cytochrome P-450 from Rhizobium japonicum

1972 • 45 citations

Cytochrome P-450 of bovine adrenal mitochondria. Ligand binding to two forms resolved by EPR spectroscopy.

1976 • 44 citations

Ligand modification of corpus luteum mitochondrial cytochrome P-450 spectra and cholesterol monooxygenation: an assay of enzyme-specific inhibitors

1977 • 43 citations

Anaerobic reductive titrations with solid diluted sodium dithionite in an apparatus suitable for EPR spectroscopy

1969 • 42 citations

Adrenal Mitochondrial Cytochrome P-450 and Cholesterol Side Chain Cleavage Activity

1973 • 40 citations

Substrate induced spin state changes in cytochrome P450

1969 • 35 citations

Cytochrome P-450 of adrenal mitochondria. Spin states as detected by difference spectroscopy.

1975 • 34 citations

Implication of Ligand Modified Spectra of Cytochrome P-450 Associated with Pregnenolone Synthesis in Mitochondria from Corpus Luteum

1975 • 2 citations