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Mass spectrometric study of the enzymatic conversion of cholesterol to (22R)-22-hydroxycholesterol, (20R,22R)-20,22-dihydroxycholesterol, and pregnenolone, and of (22R)-22-hydroxycholesterol to the lgycol and pregnenolone in bovine adrenocortical preparations. Mode of oxygen incorporation

Data up to Jan 2025

Published1975
Citations73
References15

Total Citations Per Year

Abstract

References (15)

Identification of 22‐, 24‐ and 26‐Hydroxycholesterol in the Steroid Sulphate Fraction of Faeces from Infants

1969 • 61 citations

Studies on the Biosynthetic Conversion of Cholesterol into Pregnenolone

1972 • 59 citations

Transformation of labeled cholesterol, 20α-hydroxycholesterol, (22R)-22-hydroxycholesterol, and (22R)-20α,22-dihydroxycholesterol by adrenal acetone-dried preparations from guinea pigs, cattle and man: I. Establishment of radiochemical purity of products

1970 • 53 citations

Inhibition of the biosynthesis of pregnenolone by 20α-hydroxycholesterol☆

1964 • 51 citations

Occurrence and metabolism of 20α-hydroxycholesterol in bovine adrenal preparations

1969 • 47 citations

Sterol metabolism VIII. Conversion of cholesterol 20α-hydroperoxide to 20α, 21- and 20α,22R-dihydroxycholesterol by adrenal cortex mitochondria

1970 • 44 citations

Determination of specific radioactivity of [14C]-compounds by mass spectroscopy

1972 • 43 citations

Transformation of labeled cholesterol, 20α-hydroxycholesterol, (22R)-22-hydroxycholesterol, and (22R)-20α, 22-dihydroxycholesterol by adrenal acetone-dried preparations from Guinea pigs, cattle and man: II. Kinetic studies

1970 • 41 citations

The isolation of crystalline 22R-hydroxycholesterol and 20α,22R-dihydroxycholesterol from bovine adrenals

1970 • 39 citations

Sterol metabolism. XVI. Cholesterol 20α-hydroperoxide as an intermediate in pregnenolone biosynthesis from cholesterol

1970 • 37 citations

Side-chain cleavage as related to steroid hormone synthesis

1967 • 31 citations

Enzymatic formation of (20R,22R)-20,22-dihydroxycholesterol from cholesterol and a mixture of 16O2 and 18O2: Random incorporation of oxygen atoms

1974 • 26 citations

Kinetic studies on substrate-enzyme interaction in the adrenal cholesterol side-chain cleavage system

1972 • 23 citations

Fate of molecular oxygen required by endocrine enzymes for the side-chain cleavage of cholesterol

1968 • 23 citations

Silyl derivatives of steroids. Intramolecular silylation processes and electron impact-induced reciprocal exchange of trimethylsilyl groups

1973 • 22 citations

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Mass spectrometric study of the enzymatic conversion of cholesterol to… (1975) – Journal of Biological Chemistry | Metascience Observatory Explorer