CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis.

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

1991 • 1,685 citations

Osteopontin: a protein with diverse functions

1993 • 1,082 citations

CD44 and Its Interaction with Extracellular Matrix

1993 • 1,082 citations

Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.

1992 • 1,040 citations

CD44: Structure, Function and Association with the Malignant Process

1997 • 1,004 citations

Receptor-Ligand Interaction Between CD44 and Osteopontin (Eta-1)

1996 • 930 citations

Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor α4β1

1990 • 616 citations

Integrins and cancer

1996 • 520 citations

The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro.

1995 • 508 citations

Integrin cytoplasmic interactions and bidirectional transmembrane signalling

1996 • 396 citations

Prevention of tumor metastasis formation by anti-variant CD44.

1993 • 339 citations

Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival.

1997 • 284 citations

CD44 splice variants: metastases meet lymphocytes

1993 • 268 citations

Osteopontin N-terminal Domain Contains a Cryptic Adhesive Sequence Recognized by α9β1 Integrin

1996 • 246 citations

A Biochemical Characterization of the Binding of Osteopontin to Integrins αvβ1 and αvβ5

1995 • 245 citations

Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis

1989 • 238 citations

Integrin activation: the link between ligand binding and signal transduction

1996 • 227 citations

The two major CD44 proteins expressed on a metastatic rat tumor cell line are derived from different splice variants: each one individually suffices to confer metastatic behavior.

1993 • 223 citations

Rat osteoclasts adhere to a wide range of rgd (arg-gly-asp) peptide-containing proteins, including the bone sialoproteins and fibronectin, via a β3 integrin

1992 • 215 citations

Molecular and cellular basis of genetic resistance to bacterial infection: the role of the early T-lymphocyte activation-1/osteopontin gene.

1993 • 207 citations

An Essential Role for CD44 Variant Isoforms in Epidermal Langerhans Cell and Blood Dendritic Cell Function

1997 • 176 citations

Reduced malignancy of ras-transformed NIH 3T3 cells expressing antisense osteopontin RNA.

1994 • 146 citations

Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity.

1996 • 144 citations

The role of osteopontin in tumorigenesis and metastasis.

1997 • 119 citations

Role of CD44 cytoplasmic domain in hyaluronan binding

1995 • 119 citations

Site‐directed mutagenesis of the arginine‐glycine‐aspartic acid sequence in osteopontin destroys cell adhesion and migration functions

1995 • 105 citations

Osteopontin and p53 expression are associated with tumor progression in a case of synchronous, bilateral, invasive mammary carcinomas.

1997 • 105 citations

Variant Exons v6 and v7 Together Expand the Repertoire of Glycosaminoglycans Bound by CD44

1997 • 95 citations

Hyaluronate-independent metastatic behavior of CD44 variant-expressing pancreatic carcinoma cells.

1996 • 93 citations

Orthotopic is orthodox: Why are orthotopic‐transplant metastatic models different from all other models?

1994 • 91 citations

Expression and function of fibronectin binding integrins on rat mast cells

1995 • 90 citations

Antigenic differences between metastatic and nonmetastatic BSp73 rat tumor variants characterized by monoclonal antibodies.

1989 • 83 citations

CD44 is the major peanut lectin-binding glycoprotein of human epidermal keratinocytes and plays a role in intercellular adhesion

1995 • 75 citations

Identification and functional characterization of mouse CD29 with a mAb

1995 • 57 citations

Non-RGD domains of osteopontin promote cell adhesion without involving αv integrins

1996 • 50 citations

Integrins: Role in Cell Adhesion and Communication

1996 • 47 citations

Recombinant human granulocyte colony‐stimulating factor inhibits the metastasis of hematogenous and non‐hematogenous tumors in mice

1991 • 40 citations

Functional analysis of mononuclear cells infiltrating into tumors. III. Soluble factors involved in the regulation of T lymphocyte infiltration into tumors.

1988 • 29 citations

An efficient and reliable method for cloning PCR-amplification products: a survey of point mutations in integrin cDNA.

1992 • 23 citations