Cardiac homeobox gene NKX2-5mutations and congenital heart disease

Congenital Heart Disease Caused by Mutations in the Transcription Factor NKX2-5

1998 • 1,284 citations

Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways

1999 • 667 citations

Emery and Rimoin's Principles and Practice of Medical Genetics

1997 • 508 citations

Cardiac Septal and Valvular Dysmorphogenesis in Mice Heterozygous for Mutations in the Homeobox Gene Nkx2-5

2000 • 340 citations

NKX2.5 Mutations in Patients With Tetralogy of Fallot

2001 • 333 citations

Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development.

1997 • 323 citations

The association between the diameter of a patent foramen ovale and the risk of embolic cerebrovascular events

2000 • 258 citations

Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease

2000 • 164 citations

Identification of connexin43 (α1) gap junction gene mutations in patients with hypoplastic left heart syndrome by denaturing gradient gel electrophoresis (DGGE)

2001 • 149 citations

Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein

2001 • 141 citations

Reduced Penetrance, Variable Expressivity, and Genetic Heterogeneity of Familial Atrial Septal Defects

1998 • 98 citations

Novel Point Mutation in the Cardiac Transcription Factor CSX/NKX2.5 Associated With Congenital Heart Disease.

2002 • 90 citations

Molecular Basis of Cardiovascular Disease

2010 • 64 citations

Molecular genetics of congenital heart disease

1997 • 41 citations

Co-Administration of Eplerenone with an Angiotensin-Converting Enzyme Inhibitor or an Angiotensin II Antagonist in Patients with Mild to Moderate Hypertension

2002 • 6 citations