The phenotype of a “Cdc2 kinase target site-deficient” mutant of oncoprotein 18 reveals a role of this protein in cell cycle control.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

ANIMAL CELL CYCLES AND THEIR CONTROL

1992 • 1,239 citations

A Short Polypeptide Marker Sequence Useful for Recombinant Protein Identification and Purification

1988 • 934 citations

A family of human cdc2-related protein kinases.

1992 • 928 citations

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

1991 • 884 citations

Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement

1988 • 786 citations

Cyclins and cyclin-dependent kinases: take your partners

1993 • 441 citations

Extracellular signals and reversible protein phosphorylation: What to Mek of it all

1993 • 426 citations

Braking the cycle

1993 • 378 citations

Targets of cyclin-dependent protein kinases

1993 • 240 citations

A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts

1990 • 209 citations

Identification of a polypeptide associated with the malignant phenotype in acute leukemia.

1988 • 177 citations

Multiple phosphorylation of stathmin. Identification of four sites phosphorylated in intact cells and in vitro by cyclic AMP-dependent protein kinase and p34cdc2.

1993 • 162 citations

Cyclins and their partners: from a simple idea to complicated reality.

1991 • 159 citations

Serine 25 of oncoprotein 18 is a major cytosolic target for the mitogen-activated protein kinase

1993 • 128 citations

Cell‐cycle‐regulated phosphorylation of oncoprotein 18 on Ser16, Ser25 and Ser38

1994 • 106 citations

Characterization of the gene for a proliferation-related phosphoprotein (oncoprotein 18) expressed in high amounts in acute leukemia.

1991 • 103 citations

Regulation of phosphoprotein p18 in leukemic cells. Cell cycle regulated phosphorylation by p34cdc2 kinase.

1994 • 103 citations

N-myc gene amplification in neuroblastoma is associated with altered phosphorylation of a proliferation related polypeptide (Op18).

1990 • 101 citations

Quantitative analysis of the expression and regulation of an activation-regulated phosphoprotein (oncoprotein 18) in normal and neoplastic cells.

1993 • 98 citations

A Single cDNA Encodes Two Isoforms of Stathmin, a Developmentally Regulated Neuron-enriched Phosphoprotein

1989 • 96 citations

Structural and functional basis for hormone binding and receptor oligomerization

1994 • 91 citations

Expression of oncoprotein 18 in human leukemias and lymphomas.

1993 • 85 citations

Directional antisense and sense cDNA cloning using Epstein-Barr virus episomal expression vectors

1989 • 82 citations

Phosphorylation of stathmin and other proteins related to nerve growth factor-induced regulation of PC12 cells.

1990 • 73 citations

Multiple signal transduction pathways induce phosphorylation of serines 16, 25, and 38 of oncoprotein 18 in T lymphocytes.

1993 • 71 citations

Serine 16 of Oncoprotein 18 is a Major Cytosolic Target for the Ca²⁺/Calmodulin‐Dependent Kinase‐Gr

1994 • 66 citations

Molecular Cloning of A Novel Human Leukemia-Associated Gene

1989 • 65 citations

Purification and characterization of a 19-kilodalton intracellular protein. An activation-regulated putative protein kinase C substrate of T lymphocytes.

1990 • 60 citations

Flow cytometric analysis of proliferation associated nuclear antigens using washless staining of unfixed cells

1992 • 53 citations

Phorbol 12-myristate 13-acetate-induced phosphorylation of Op18 in Jurkat T cells. Identification of phosphorylation sites by matrix-assisted laser desorption ionization mass spectrometry

1993 • 47 citations

Widespread differentiation stage-specific expression of the gene encoding phosphoprotein p19 (metablastin) in mammalian cells

1992 • 47 citations

T cell receptor activation induces rapid phosphorylation of prosolin, which mediates down-regulation of DNA synthesis in proliferating peripheral lymphocytes.

1991 • 35 citations

Analysis of phosphoprotein p19 by liquid chromatography/mass spectrometry. Identification of two proline-directed serine phosphorylation sites and a blocked amino terminus.

1992 • 35 citations

Expression of the leukemia-associated gene, p18, in normal and malignant tissues; inactivation of expression in a patient with cleaved B cell lymphoma/leukemia.

1993 • 30 citations