Anti-tumor necrosis factor alpha therapy suppresses the induction of experimental autoimmune uveoretinitis in mice by inhibiting antigen priming.

Statistical Methods -6th ed.-

1967 • 6,747 citations

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1975 • 4,522 citations

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

Induction of apoptosis in mature T cells by tumour necrosis factor

1995 • 1,139 citations

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis.

1990 • 692 citations

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1990 • 540 citations

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1991 • 485 citations

Uveitis: Fundamentals and Clinical Practice

1990 • 467 citations

A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens.

1988 • 451 citations

Cachectin/tumor necrosis factor exerts endocrine, paracrine, and autocrine control of inflammatory responses.

1988 • 441 citations

Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes.

1987 • 372 citations

T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat.

1986 • 358 citations

Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha.

1995 • 348 citations

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process.

1994 • 300 citations

Chapter 3 Retinal specific antigens and immunopathogenic processes they provoke

1986 • 289 citations

Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity

1990 • 285 citations

Natural killer (NK) cell-derived hematopoietic colony-inhibiting activity and NK cytotoxic factor. Relationship with tumor necrosis factor and synergism with immune interferon.

1985 • 249 citations

Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor.

1992 • 234 citations

Tumor necrosis factor in the pathophysiology of infection and sepsis

1990 • 233 citations

Enhancement of antigen- and mitogen-induced human T lymphocyte proliferation by tumor necrosis factor-alpha.

1988 • 221 citations

Human Corticotropin-Releasing Factor in Man: Pharmacokinetic Properties and Dose-Response of Plasma Adrenocorticotropin and Cortisol Secretion

1984 • 206 citations

Hypothesis: A role for tumor necrosis factor in immune-mediated demyelination and its relevance to multiple sclerosis

1988 • 199 citations

Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I

1995 • 177 citations

Cytokines in human intraocular inflammation

1992 • 156 citations

Ocular inflammatory effects of intravitreally-injected tumor necrosis factor.

1988 • 150 citations

Cytokines and uveitis, a review

1992 • 146 citations

Neutralization of endogenous tumor necrosis factor ameliorates the severity of myosin-induced myocarditis.

1992 • 131 citations

Cytotoxic effect of TNF and lymphotoxin on T lymphoblasts.

1995 • 119 citations

Mechanisms that regulate the production and effects of tumor necrosis factor-alpha.

1989 • 115 citations

Neutralization of endogenous tumor necrosis factor ameliorates the severity of myosin-induced myocarditis.

1992 • 94 citations

Mechanisms of tumor necrosis factor-alpha alteration of PMN adhesion and migration.

1990 • 93 citations

FUNCTIONAL PROPERTIES OF INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN

1991 • 90 citations

The role of tumor necrosis factor-alpha in the induction of experimental autoimmune uveoretinitis in mice.

1994 • 88 citations

In vitro production of rabbit macrophage tumor cell cytotoxin

1983 • 83 citations

Cytokine Assays: Role in Evaluation of the Pathogenesis of Autoimmunity

1991 • 83 citations

Recruitment of antigen-nonspecific cells plays a pivotal role in the pathogenesis of a T cell-mediated organ-specific autoimmune uveoretinitis

1993 • 80 citations

Differential tumor necrosis factor expression by resident retinal cells from experimental uveitis-susceptible and -resistant rat strains

1994 • 74 citations

Ocular inflammatory effects of intravitreally injected tumor necrosis factor-alpha and endotoxin

1990 • 73 citations

Inhibition of neutrophil migration by tumor necrosis factor. Ex vivo and in vivo studies in comparison with in vitro effect.

1990 • 68 citations

Anti-tumor necrosis factor antibodies suppress cell-mediated immunity in vivo.

1992 • 61 citations

Uveitogenic T lymphocytes in the rat: pathogenicity vs. lymphokine production, adhesion molecules and surface antigen expression

1994 • 30 citations

Basic Mechanisms in Immune-mediated Uveitic Disease

1989 • 27 citations

Multiple sclerosis: immunological findings and possible implications for therapy

1992 • 26 citations

Cachectin: A novel polypeptide induces uveitis in the rabbit eye

1988 • 23 citations