Interleukin 1 in Crohn's disease.

Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study.

1976 • 3,140 citations

Cortisone in Ulcerative Colitis

1955 • 2,701 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

Interleukin-1 and the Pathogenesis of the Acute-Phase Response

1984 • 1,136 citations

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 921 citations

Interleukin 1, a potential regulator of fibroblast proliferation.

1982 • 835 citations

Stimulation of Muscle Protein Degradation and Prostaglandin E₂Release by Leukocytic Pyrogen (Interleukin-1)

1983 • 689 citations

Muscle Proteolysis Induced by a Circulating Peptide in Patients with Sepsis or Trauma

1983 • 469 citations

Rapid identification of monocytes in a mixed mononuclear cell preparation

1977 • 330 citations

Purification to apparent homogeneity of murine interleukin 1.

1981 • 257 citations

Endogenous Pyrogen Activity in Human Plasma After Exercise

1983 • 256 citations

Human keratinocytes and monocytes release factors which regulate the synthesis of major acute phase plasma proteins in hepatic cells from man, rat, and mouse.

1984 • 225 citations

The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen

1981 • 224 citations

Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.

1978 • 206 citations

Cytokines and the chronic inflammation of rheumatic disease. I. The presence of interleukin-1 in synovial fluids.

1984 • 186 citations

Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes.

1984 • 136 citations

Potentiation of Cultured Mouse Thymocyte Responses by Factors Released by Peripheral Leucocytes

1971 • 124 citations

Induction of fibroblast proliferation by interleukin‐1 derived from human monocytic leukemia cells

1984 • 123 citations

Effect of inflammatory agents and interleukin 1 on iron and zinc metabolism

1984 • 116 citations

Interleukin-2 Dependent Culture of Cytolytic T Cell Lines

1981 • 102 citations

Enhancement of DNA Synthesis and cAMP Content of Mouse Thymocytes by Mediator(s) Derived from Adherent Cells

1976 • 91 citations

Characterization of a human interleukin 1 inhibitor.

1985 • 87 citations

LEUKOCYTIC PYROGEN: A MAJOR MEDIATOR OF THE ACUTE PHASE REACTION

1982 • 76 citations

An Endogenous Mediator of Depression of Amino Acids and Trace Metals in Serum during Typhoid Fever

1972 • 75 citations

Macrophage activation, chronic inflammation and gastrointestinal disease.

1984 • 70 citations

Role of the central nervous system in acute-phase responses to leukocytic pyrogen

1980 • 64 citations

Veiled cells in chronic idiopathic inflammatory bowel disease.

1984 • 62 citations

Interleukin 2‐independent stimulation of rabbit chondrocyte collagenase and prostaglandin E₂ production by an interleukin 1‐like factor

1984 • 58 citations

Stimulation of interleukin-1 production from placental monocytes.

1984 • 56 citations

Modulation of connective tissue metabolism by partially purified human interleukin 1

1985 • 49 citations

CHARACTERIZATION OF A LEUKOCYTE‐DERIVED ENDOGENOUS MEDIATOR RESPONSIBLE FOR INCREASED PLASMA FIBRINOGEN

1982 • 44 citations

Immunology of Inflammatory Bowel Disease

1985 • 44 citations

Spontaneous production of Interleukin-1 by human alveolar macrophages

1983 • 37 citations

Interleukin 1 production by peripheral blood mononuclear cells from leprosy patients

1984 • 37 citations

Constitutive secretion of interleukin 1 by human monocytes

1983 • 35 citations

Effect of leukocytic endogenous mediators on endocrine pancreas secretory responses.

1977 • 34 citations

Anergy in sarcoidosis: the role of interleukin-1 and prostaglandins in the depressed in vitro lymphocyte response.

1984 • 27 citations

Production of lymphocyte activating factor in vivo.

1983 • 7 citations

Antimetastatic effect of cimetidine on mice bearing a C3H mouse mammary adenocarcinoma: survival and lymphocyte function studies

1984 • 4 citations