Cutting Edge: Both Activating and Inhibitory Fc Receptors Expressed on Mast Cells Regulate Experimental Allergic Encephalomyelitis Disease Severity

Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes.

1989 • 2,118 citations

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

2002 • 1,644 citations

Multiple Sclerosis: A Coordinated Immunological Attack against Myelin in the Central Nervous System

1996 • 903 citations

Identification of autoantibodies associated with myelin damage in multiple sclerosis

1999 • 881 citations

Roles of Fc receptors in autoimmunity

2002 • 609 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity

2002 • 496 citations

Mast Cells Are Essential for Early Onset and Severe Disease in a Murine Model of Multiple Sclerosis

2000 • 427 citations

Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity

2002 • 384 citations

Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis.

1997 • 363 citations

Roles of mast cells and basophils in innate and acquired immunity

2000 • 350 citations

Substance P selectively activates TNF-alpha gene expression in murine mast cells.

1993 • 333 citations

Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: A case for antigen-specific antibody mediation

1999 • 289 citations

Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis

1997 • 267 citations

B cells and antibodies in CNS demyelinating disease

2001 • 246 citations

An unexpected version of horror autotoxicus: anaphylactic shock to a self-peptide

2001 • 187 citations

Cutting Edge: VacA, a Vacuolating Cytotoxin of Helicobacter pylori, Directly Activates Mast Cells for Migration and Production of Proinflammatory Cytokines

2002 • 151 citations

Fc Receptors are Critical for Autoimmune Inflammatory Damage to the Central Nervous System in Experimental Autoimmune Encephalomyelitis

2002 • 96 citations

Immunoglobulin G Fc-receptor (FcγR) IIA and IIIB polymorphisms related to disability in MS

1999 • 88 citations

Autoimmunity through infection or immunization?

2001 • 78 citations

Mechanisms underlying mast cell influence on EAE disease course

2002 • 69 citations

Activating and inhibitory signaling in mast cells: New opportunities for therapeutic intervention?

2000 • 67 citations

Further Characterization of FcγRII and FcγRIII Expression by Cultured Human Mast Cells

2001 • 43 citations