Evidence that a G-protein transduces signals initiated by the protein-tyrosine kinase v-Fps

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

The GTPase superfamily: a conserved switch for diverse cell functions

1990 • 2,330 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Requirement for c-ras proteins during viral oncogene transformation

1986 • 680 citations

The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding.

1982 • 542 citations

Involvement of guanine nucleotide-binding protein in the gating of Ca2+ by receptors

1983 • 473 citations

Dissociation of bradykinin-induced prostaglandin formation from phosphatidylinositol turnover in Swiss 3T3 fibroblasts: evidence for G protein regulation of phospholipase A2.

1987 • 375 citations

Molecular cloning, characterization, and expression of a cDNA encoding the "80- to 87-kDa" myristoylated alanine-rich C kinase substrate: a major cellular substrate for protein kinase C.

1989 • 318 citations

Oncogenes, Growth Factors, and Signal Transduction

1989 • 296 citations

Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein

1987 • 206 citations

Evidence for involvement of guanine nucleotide‐binding regulatory proteins in the activation of phospholipases by hormones

1988 • 190 citations

Specific binding of [alpha-32P]GTP to cytosolic and membrane-bound proteins of human platelets correlates with the activation of phospholipase C.

1987 • 157 citations

Constitutive expression of a gene encoding a polypeptide homologous to biologically active human platelet protein in Rous sarcoma virus-transformed fibroblasts.

1987 • 129 citations

Bombesin, diacylglycerols, and phorbol esters rapidly stimulate the phosphorylation of an Mr = 80,000 protein kinase C substrate in permeabilized 3T3 cells. Effect of guanine nucleotides.

1988 • 120 citations

Pertussis toxin or phorbol 12-myristate 13-acetate can distinguish between epidermal growth factor- and angiotensin-stimulated signals in hepatocytes.

1986 • 101 citations

Insulin-dependent phosphorylation of GTP-binding proteins in phospholipid vesicles.

1988 • 99 citations

A pertussis toxin-sensitive G-protein mediates some aspects of insulin action in BC3H-1 murine myocytes.

1990 • 94 citations

Colony-stimulating factor 1-induced Na+ influx into human monocytes involves activation of a pertussis toxin-sensitive GTP-binding protein.

1988 • 69 citations

Mutants of Fujinami sarcoma virus which are temperature sensitive for cellular transformation and protein kinase activity

1981 • 66 citations

Evidence that v-src and v-fps gene products use a protein kinase C-mediated pathway to induce expression of a transformation-related gene.

1989 • 55 citations

Insulin stimulates a novel GTPase activity in human platelets

1987 • 37 citations

The roles of phospholipase D and a GTP-binding protein in guanosine 5′-[γ-thio]triphosphate-stimulated hydrolysis of phosphatidylcholine in rat liver plasma membranes

1990 • 32 citations

Cholera toxin induces expression of the immediate-early response gene JE via a cyclic AMP-independent signaling pathway.

1991 • 20 citations

Induction of an unusual type of shared phosphorylation in human and avian cells by tumor-promoting phorbol esters or transformation.

1986 • 16 citations

Platelet cytosolic 44-kDa protein is a substrate of cholera toxin-induced ADP-ribosylation and is not recognized by antisera against the alpha subunit of the stimulatory guanine nucleotide-binding regulatory protein.

1988 • 13 citations