Purification and characterization of an inactive form of cAMP-dependent protein kinase containing bound cAMP.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A Method for Determining the Sedimentation Behavior of Enzymes: Application to Protein Mixtures

1961 • 5,561 citations

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

1966 • 2,239 citations

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

[1] Assays of protein kinase

1983 • 832 citations

The distribution and dissociation of cyclic adenosine 3':5'-monophosphate-dependent protein kinases in adipose, cardiac, and other tissues.

1975 • 758 citations

The enzymatic preparation of [α-32P]nucleoside triphosphates, cyclic [32P]AMP, and cyclic [32P]GMP

1979 • 574 citations

Comparison of adenosine 3':5'-monophosphate-dependent protein kinases from rabbit skeletal and bovine heart muscle.

1975 • 569 citations

Studies on the properties and mode of action of the purified regulatory subunit of bovine heart adenosine 3‘:5‘-monophosphate-dependent protein kinase.

1978 • 467 citations

Regulatory Mechanisms in the Control of Protein Kinase

1982 • 357 citations

Purification and characterization of catalytic subunit of skeletal muscle adenosine 3':5'-monophosphate-dependent protein kinase.

1977 • 328 citations

Purification and characterization of the catalytic subunit of adenosine 3':5'-cyclic monophosphate-dependent protein kinase from bovine liver

1976 • 295 citations

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

1986 • 286 citations

Phosphorylation of a Cyclic Adenosine 3′ : 5′-Monophosphate-dependent Protein Kinase from Bovine Cardiac Muscle

1974 • 253 citations

Characterization and regulation of heart adenosine 3':5'-monophosphate-dependent protein kinase isozymes.

1977 • 207 citations

A cloned bovine cDNA encodes an alternate form of the catalytic subunit of cAMP-dependent protein kinase.

1986 • 206 citations

Protein Phosphorylation Catalyzed by Cyclic AMP-Dependent and Cyclic GMP-Dependent Protein Kinases

1980 • 201 citations

Two different intrachain cAMP binding sites of cAMP-dependent protein kinases.

1980 • 189 citations

Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase.

1981 • 188 citations

Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues

1976 • 164 citations

Amino acid sequence of the regulatory subunit of bovine type II cAMP-dependent protein kinase

1984 • 128 citations

Effect of cAMP and ATP on the reassociation of phosphorylated and nonphosphorylated subunits of the cAMP-dependent protein kinase from bovine cardiac muscle.

1977 • 124 citations

The mechanism of activation of bovine skeletal muscle protein kinase by adenosine 3‘:5‘-monophosphate.

1980 • 115 citations

Stoichiometry of cAMP binding and limited proteolysis of protein kinase regulatory subunits R I and R II

1979 • 115 citations

Magnetic resonance studies of the effect of the regulatory subunit on metal and substrate binding to the catalytic subunit of bovine heart protein kinase.

1980 • 82 citations

Microheterogeneity of type II cAMP-dependent protein kinase in various mammalian species and tissues.

1984 • 81 citations

Sulfhydryl group reactivity of adenosine 3',5'-monophosphate dependent protein kinase from bovine heart: a probe of holoenzyme structure

1978 • 74 citations

Studies on the function of the two intrachain cAMP binding sites of protein kinase.

1981 • 73 citations

cAMP-dependent protein kinase activation lowers hepatocyte cAMP.

1985 • 67 citations

[7] Regulatory subunits of bovine heart and rabbit skeletal muscle cAMP-dependent protein kinase isozymes

1983 • 67 citations

Effect of Cyclic Nucleotide Analogs on Intrachain Site 1 of Protein Kinase Isozymes

1982 • 66 citations

Characterization of the interchain and intrachain interactions between the binding sites of the free regulatory moiety of protein kinase I.

1984 • 64 citations

Cyclic AMP-dependent protein kinase I: Cyclic nucleotide binding, structural changes, and release of the catalytic subunits

1981 • 59 citations

Conversion of bovine cardiac adenosine cyclic 3',5'-phosphate dependent protein kinase to a heterodimer by removal of 45 residues at the N-terminus of the regulatory subunit

1986 • 50 citations

Kinetic studies on the dissociation of adenosine cyclic 3',5'-monophosphate from the regulatory subunit of protein kinase from rabbit skeletal muscle

1980 • 46 citations

Activation of type I cyclic AMP-dependent protein kinases with defective cyclic AMP-binding sites.

1987 • 39 citations

The regulatory subunit monomer of cAMP-dependent protein kinase retains the salient kinetic properties of the native dimeric subunit.

1985 • 34 citations

Identification of a ternary complex between cAMP and a trimeric form of cAMP-dependent protein kinase.

1986 • 22 citations

Stimulation of [3H]cIMP binding by cAMP analogs in extracts of perfused rat hearts.

1982 • 7 citations