Characterization of the interchain and intrachain interactions between the binding sites of the free regulatory moiety of protein kinase I.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Thermodynamics of protein association reactions: forces contributing to stability

1981 • 5,079 citations

Protein Phosphorylation

1975 • 762 citations

Site-site interactions among insulin receptors. Characterization of the negative cooperativity.

1976 • 601 citations

Mechanism of Activation of Catabolite-Sensitive Genes: A Positive Control System

1970 • 430 citations

Protein Kinases* *Support of the National Institutes of Arthritis and Metabolic Diseases, NIH, U. S. Public Health Service (AM 12842), the Muscular Dystrophy Association of America, and the American Heart Association is acknowledged.

1972 • 416 citations

Regulatory Mechanisms in the Control of Protein Kinase

1982 • 357 citations

Slow Transitions and Hysteretic Behavior in Enzymes

1979 • 292 citations

Concentrations of cyclic AMP-dependent protein kinase subunits in various tissues.

1977 • 270 citations

Enzymes: Physical principles

1973 • 245 citations

Structure of catabolite gene activator protein at 2.9-A resolution. Incorporation of amino acid sequence and interactions with cyclic AMP.

1982 • 229 citations

Quantitative aspects of hormone-receptor interactions of high affinity

1975 • 210 citations

Reduction of aryl azides by thiols: Implications for the use of photoaffinity reagents

1978 • 208 citations

Estradiol-binding kinetics of the activated and nonactivated estrogen receptor.

1977 • 191 citations

Two different intrachain cAMP binding sites of cAMP-dependent protein kinases.

1980 • 189 citations

Positive cooperativity of the estrogen receptor.

1981 • 173 citations

Relationships between structural domains and function in the regulatory subunit of cAMP-dependent protein kinases I and II from porcine skeletal muscle

1979 • 134 citations

Role of hydrophobicity in the binding of coenzymes

1978 • 133 citations

The cAMP-binding domains of the regulatory subunit of cAMP-dependent protein kinase and the catabolite gene activator protein are homologous.

1982 • 132 citations

The mechanism of activation of bovine skeletal muscle protein kinase by adenosine 3‘:5‘-monophosphate.

1980 • 115 citations

An equilibrium study of the cooperative binding of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate to the adenosine cyclic 3',5'-monophosphate receptor protein from Escherichia coli

1980 • 112 citations

Interaction of cAMP Derivatives with the ‘Stable’ CAMP‐Binding Site in the CAMP‐Dependent Protein Kinase Type I

1982 • 111 citations

The reaction between thiols and 8-azidoadenosine derivatives

1976 • 108 citations

Probable involvement of both intrachain cAMP binding sites in activation of protein kinase.

1983 • 106 citations

Stoichiometry of cAMP and 1,N6-etheno-cAMP binding to protein kinase.

1980 • 103 citations

Evidence that rabbit muscle protein kinase has two kinetically distinct binding sites for adenosine 3′; 5′-cyclic monophosphate

1978 • 98 citations

Studies of two different intrachain cGMP-binding sites of cGMP-dependent protein kinase.

1983 • 96 citations

The kinetics of association of cyclic AMP to the two types of binding sites associated with protein kinase II from bovine myocardium

1981 • 73 citations

Binding proteins for cyclic AMP in mammalian tissues

1981 • 72 citations

Mechanism of the isotopic exchange of the C-8 hydrogen of purines in nucleosides and in deoxyribonucleic acid

1972 • 69 citations

Effect of Cyclic Nucleotide Analogs on Intrachain Site 1 of Protein Kinase Isozymes

1982 • 66 citations

Properties of regulatory subunit of cyclic AMP-dependent protein kinase (peak I) from rabbit skeletal muscle prepared by urea treatment of the holoenzyme.

1977 • 61 citations

Mapping of the two intrachain cyclic nucleotide binding sites of adenosine cyclic 3',5'-phosphate dependent protein kinase I

1983 • 61 citations

Cyclic AMP-dependent protein kinase I: Cyclic nucleotide binding, structural changes, and release of the catalytic subunits

1981 • 59 citations

Evidence that cyclic nucleotides activating rabbit muscle protein kinase I interact with both types of cAMP binding sites associated with the enzyme.

1983 • 59 citations

Site-specific cyclic nucleotide binding and dissociation of the holoenzyme of cAMP-dependent protein kinase.

1982 • 47 citations

Kinetic studies on the dissociation of adenosine cyclic 3',5'-monophosphate from the regulatory subunit of protein kinase from rabbit skeletal muscle

1980 • 46 citations

The kinetics of the interaction between cyclic AMP and the regulatory moiety of protein kinase II

1981 • 45 citations

Activation of protein kinase isoenzymes under near physiological conditions

1982 • 45 citations

Protein kinase II has two distinct binding sites for cyclic AMP, only one of which is detectable by the conventional membrane‐filtration method

1980 • 42 citations

Bovine lung cyclic GMP-dependent protein kinase exhibits two types of specific cyclic GMP-binding sites.

1982 • 41 citations

Comparison of some physicochemical and kinetic properties of S-Adenosylhomocysteine hydrolase from bovine liver, bovine adrenal cortex and mouse liver

1982 • 37 citations

Binding proteins for adenosine 3′:5′-cyclic monophosphate in bovine adrenal cortex

1977 • 35 citations

Spectroscopic studies of the cAMP binding sites of the regulatory subunits of types I and II protein kinase.

1980 • 33 citations

Equilibrium ligand binding assays using labeled substrates: Nature of the errors introduced by radiochemical impurities

1978 • 33 citations

Release of [3H]adenosine cyclic 3',5'-phosphate bound to the regulatory moiety of protein kinase I in the presence of magnesium(2+), ATP and the catalytic subunit of the kinase

1983 • 32 citations

A pitfall in the interpretation of data on ligand-protein interaction

1975 • 32 citations

Mechanism of Activation of Protein Kinase I from Rabbit Skeletal Muscle. The Equilibrium Parameters of Ligand Interaction and Protein Dissociation

1978 • 29 citations

Perturbation and structural organization of the two intrachain cAMP binding sites of cAMP-dependent protein kinase II.

1981 • 27 citations

Characterization of Phosphorylated and Dephosphorylated Regulatory Subunit of CAMP-Dependent Protein Kinase II

1982 • 23 citations

Measurement of adenosine 3′:5′-cyclic monophosphate by competitive binding to salt-dissociated protein kinase

1978 • 23 citations

Acyl-CoA synthetase activity of brown adipose tissue mitochondria substrate specificity and its relation to the endogenous pool of long-chain fatty acids

1980 • 20 citations

Measurement of adenylate cyclase activity by competitive binding to the free regulatory moiety of protein kinase I

1980 • 16 citations

Binding of 5,5'-bis[8-(phenylamino)-1-naphthalenesulfonate] by the regulatory subunits of adenosine cyclic 3',5'-phosphate dependent protein kinase

1982 • 12 citations

An adenosine 3′:5′-monophosphate-adenosine binding protein from mouse liver

1978 • 10 citations

Reconstitution of type I and II adenosine cyclic 3',5'-phosphate dependent protein kinase

1982 • 5 citations