New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo.

TISSUE SULPHYDRYL GROUPS

1959 • 1,486 citations

Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent

1978 • 1,226 citations

The kinetics of antibody binding to membrane antigens in solution and at the cell surface

1980 • 568 citations

Immunotoxins: A New Approach to Cancer Therapy

1983 • 282 citations

Dynamic state of glutathione in blood plasma.

1980 • 249 citations

The Preparation and Cytotoxic Properties of Antibody‐Toxin Conjugates

1982 • 199 citations

Effect of chemical deglycosylation of ricin A chain on the in vivo fate and cytotoxic activity of an immunotoxin composed of ricin A chain and anti-Thy 1.1 antibody.

1987 • 134 citations

Studies on the structure and properties of the lectins from Abrus precatorius and Ricinus communis

1975 • 118 citations

Modification of the carbohydrate in ricin with metaperiodate — cyanoborohydride mixtures

1985 • 117 citations

Study of the plasma clearance of antibody – ricin‐A‐chain immunotoxins

1986 • 116 citations

Direct Determinations of Plasma, Cell, and Organ-Blood Volumes in Normal and Hypervolemic Mice

1950 • 101 citations

[16] Preparation of antibody—toxin conjugates

1985 • 99 citations

Importance of the Antigen-Binding Valency and the Nature of the Cross-Linking Bond in Ricin A-Chain Conjugates with Antibody

1982 • 84 citations

Purification of immunotoxins containing ricin A-chain and abrin A-chain using Blue Sepharose CL-6B

1987 • 79 citations

In vivo administration of lymphocyte-specific monoclonal antibodies in nonhuman primates. In vivo stability of disulfide-linked immunotoxin conjugates.

1986 • 70 citations

Antibody Toxin Conjugates: A Perspective

2015 • 66 citations

Fate of an antibody-ricin a chain conjugate administered to normal rats

1986 • 46 citations

Effect of linkage variation on pharmacokinetics of ricin A chain-antibody conjugates in normal rats.

1986 • 45 citations

Immunotoxins Containing Ricin A Or B Chains with Modified Carbohydrate Residues Act Synergistically in Killing Neoplastic B CellsIn Vitro*

1985 • 20 citations