T-cell receptor transgenic analysis of tumor-specific CD8 and CD4 responses in the eradication of solid tumors.

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

1998 • 2,615 citations

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1998 • 2,373 citations

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

1998 • 2,106 citations

Determination of lymphocyte division by flow cytometry

1994 • 1,712 citations

Antitumor and antimetastatic activity of interleukin 12 against murine tumors.

1993 • 1,206 citations

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.

1987 • 1,166 citations

Tumor Rejection After Direct Costimulation of CD8 ⁺ T Cells by B7-Transfected Melanoma Cells

1993 • 1,154 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

1990 • 926 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

1988 • 505 citations

A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity

1994 • 347 citations

CD4+ T Cell Help Impairs CD8+ T Cell Deletion Induced by Cross-presentation of Self-Antigens and Favors Autoimmunity

1997 • 320 citations

Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy

1997 • 316 citations

CD8(+) T cell-mediated spontaneous diabetes in neonatal mice.

1996 • 276 citations

Active immunotherapy of cancer with a nonreplicating recombinant fowlpox virus encoding a model tumor-associated antigen.

1995 • 222 citations

Peripheral tolerance to an islet cell‐specific hemagglutinin transgene affects both CD4⁺ and CD8⁺ T cells

1992 • 217 citations

Antigenic Cancer Cells Grow Progressively in Immune Hosts without Evidence for T Cell Exhaustion or Systemic Anergy

1997 • 205 citations

Cytolytic T-cell clones against an autologous human melanoma: specificity study and definition of three antigens by immunoselection.

1989 • 188 citations

Establishment of a murine model of malignant mesothelioma

1992 • 184 citations

Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells.

1992 • 169 citations

Tumor antigens recognized by T lymphocytes

1997 • 153 citations

Molecular Mechanisms Used by Tumors to Escape Immune Recognition

1993 • 120 citations

Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity.

1988 • 118 citations

T‐Cell Immunotherapy of Tumors by Adoptive Transfer of Cytotoxic T Lymphocytes and by Vaccination with Minimal Essential Epitopes

1995 • 115 citations

Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice.

1996 • 101 citations

Transforming Growth Factor-Beta: Antisense RNA-Mediated Inhibition Affects Anchorage-Independent Growth, Tumorigenicity and Tumor-Infiltrating T-Cells in Malignant Mesothelioma

1994 • 91 citations

Prolonged survival of thymoma-bearing mice after vaccination with a soluble protein antigen entrapped in liposomes: a model study.

1992 • 78 citations

Timely immunization subverts the development of peripheral nonresponsiveness and suppresses tumor development in simian virus 40 tumor antigen-transgenic mice.

1994 • 74 citations

Multiple lineages of tumors express a common tumor antigen, P1A, but they are not cross-protected.

1995 • 71 citations

CD8 T Cells Are Not Required for Islet Destruction Induced by a CD4+ Islet-Specific T-Cell Clone

1992 • 69 citations

Defects in cell‐mediated immunity during growth of a syngeneic simian virus‐induced tumor

1975 • 62 citations

The role of CD4+ tumor-infiltrating lymphocytes in human solid tumors

1995 • 57 citations

Patho- and immunobiology of malignant mesothelioma: characterisation of tumour infiltrating leucocytes and cytokine production in a murine model

1994 • 54 citations

Neoplastic cells that express low levels of MHC class I determinants escape host immunity.

1994 • 47 citations

Altered CD3 chain and cytokine gene expression in tumor infiltrating T lymphocytes during the development of mesothelioma

1996 • 38 citations

Tumor-infiltrating lymphocytes: evidence for specific immune reactions against growing cancers in mice and humans.

1990 • 29 citations

Recognition and Lysis of Human Melanoma by a CD3+, CD4+, CD8−T-Cell Clone Restricted by HLA-A2

1996 • 27 citations

The induction of immune responses to murine malignant mesothelioma by IL‐2 gene transfer

1997 • 22 citations

In vitro and in vivo immunosuppressive effects of supernatants from human choriocarcinoma cell lines

1991 • 19 citations

TRANSFECTION OF MAJOR HISTOCOMPATIBLITY COMPLEX CLASS I AND CLASS II GENES CAUSES TUMOUR REJECTION

1989 • 17 citations

Induction of experimental autoimmune encephalomyelitis by native myelin basic protein‐activated T lymphocyte lines

1992 • 3 citations