Cysteine in the triple-helical domain of one allelic product of the alpha 1(I) gene of type I collagen produces a lethal form of osteogenesis imperfecta.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

Genetic heterogeneity in osteogenesis imperfecta.

1979 • 2,147 citations

Structurally Distinct Collagen Types

1980 • 1,078 citations

The Biosynthesis of Collagen and Its Disorders

1979 • 1,067 citations

The Metabolic Basis of Inherited Disease

1983 • 757 citations

Osteogenesis Imperfecta

1981 • 378 citations

Proteolytic enzymes as probes for the triple-helical conformation of procollagen

1981 • 334 citations

Some Properties of the Products of Reaction of Tadpole Collagenase with Collagen^*

1967 • 246 citations

An improved method for determining specific radioactivities of proline-14C and hydroxyproline-14C in collagen and in noncollagenous proteins

1974 • 244 citations

Abnormal collagen metabolism in cultured cells in osteogenesis imperfecta.

1975 • 189 citations

Internal deletion in a collagen gene in a perinatal lethal form of osteogenesis imperfecta

1983 • 180 citations

Human skin fibroblast collagenase: chemical properties of precursor and active forms

1978 • 175 citations

Osteogenesis imperfecta type II delineation of the phenotype with reference to genetic heterogeneity

1984 • 173 citations

Heritable Disorders of Connective Tissue

1973 • 171 citations

Reduced secretion of structurally abnormal type I procollagen in a form of osteogenesis imperfecta.

1981 • 170 citations

Evidence for a structural mutation of procollagen type I in a patient with the Ehlers-Danlos syndrome type VII.

1980 • 160 citations

Abnormal collagen fibril structure in the gravis form (type I) of Ehlers-Danlos syndrome.

1979 • 156 citations

Altered Relation of Two Collagen Types in Osteogenesis Imperfecta

1977 • 143 citations

Type I osteogenesis imperfecta: a nonfunctional allele for pro alpha 1 (I) chains of type I procollagen.

1982 • 137 citations

Synthesis and processing of a type I procollagen containing shortened pro-alpha 1(I) chains by fibroblasts from a patient with osteogenesis imperfecta.

1983 • 121 citations

Synthesis of a shortened pro-alpha 2(I) chain and decreased synthesis of pro-alpha 2(I) chains in a proband with osteogenesis imperfecta.

1983 • 107 citations

Osteogenesis imperfecta congenita: evidence for a generalized molecular disorder of collagen.

1977 • 106 citations

Formation of the Triple Helix of Type I Procollagen in cellulo. A Kinetic Model Based on cis-trans Isomerization of Peptide Bonds

1981 • 105 citations

Chain assembly intermediate in the biosynthesis of type III procollagen in chick embryo blood vessels.

1981 • 83 citations

Disorder of collagen metabolism in a patient with osteogenesis imperfecta (lethal type): increased degree of hydroxylation of lysine in collagen types I and III

1981 • 82 citations

Bone collagen metabolism in vitamin D deficiency (Short Communication)

1973 • 64 citations

Peptide Mapping of Collagen Chains Using CNBr Cleavage of Proteins Within Polyacrylamide Gels

1981 • 63 citations

Termination of procollagen chain synthesis by puromycin. Evidence that assembly and secretion require a COOH-terminal extension.

1976 • 61 citations

Covalent structure of collagen: amino acid sequence of .alpha.1(III)-CB9 from type III collagen of human liver

1981 • 60 citations

A new rapid method for measuring hydroxylsine and its glycosides in hydrolysates and physiological fluids

1973 • 55 citations

Cyanogen bromide cleavage of proteins in sodium dodecyl sulphate/polyacrylamide gels Diagonal peptide mapping of proteins from epidermis

1981 • 45 citations

Intracellular degradation of newly synthesized collagen is conformation‐dependent

1981 • 40 citations

Synthesis and degradation of collagen by skin fibroblasts from controls and from patients with osteogenesis imperfecta

1979 • 39 citations

The prenatal diagnosis of osteogenesis imperfecta congenita

1975 • 31 citations

Changes in synthesis of types-I and -III collagen during matrix-induced endochondral bone differentiation in rat

1980 • 30 citations

The brittle bone syndrome — Osteogenesis imperfecta

1984 • 25 citations

Osteogenesis Imperfecta: Promising Beginnings and Continuing Challenges

1981 • 20 citations

Collagen genes

1982 • 8 citations