Sarcoplasmic reticulum calcium pump in cardiac and slow twitch skeletal muscle but not fast twitch skeletal muscle undergoes phosphorylation by endogenous and exogenous Ca2+/calmodulin-dependent protein kinase. Characterization of optimal conditions for calcium pump phosphorylation.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Amino-acid sequence of a Ca2+ + Mg2+ -dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence

1985 • 1,126 citations

Effects of pH on the myofilaments and the sarcoplasmic reticulum of skinned cells from cardiace and skeletal muscles.

1978 • 1,086 citations

[31] Computer programs for calculating total from specified free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands

1988 • 1,048 citations

The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase.

1975 • 917 citations

Two Ca2+ ATPase genes: Homologies and mechanistic implications of deduced amino acid sequences

1986 • 812 citations

Functional comparisons between isoforms of the sarcoplasmic or endoplasmic reticulum family of calcium pumps.

1992 • 649 citations

Molecular cloning of cDNA encoding the Ca2+ release channel (ryanodine receptor) of rabbit cardiac muscle sarcoplasmic reticulum.

1990 • 617 citations

Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity

1991 • 499 citations

Rapid calcium release from cardiac sarcoplasmic reticulum vesicles is dependent on Ca2+ and is modulated by Mg2+, adenine nucleotide, and calmodulin.

1987 • 489 citations

Concerted regulation of cardiac sarcoplasmic reticulum calcium transport by cyclic adenosine monophosphate dependent and calcium-calmodulin-dependent phosphorylations

1979 • 454 citations

Mechanism of Calcium Transport

1985 • 453 citations

Nature and site of phospholamban regulation of the Ca2+ pump of sarcoplasmic reticulum

1989 • 449 citations

Phosphorylation of the Sarcoplasmic Reticulum and Sarcolemma

1982 • 441 citations

Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains.

1986 • 435 citations

Adult forms of the Ca2+ATPase of sarcoplasmic reticulum. Expression in developing skeletal muscle.

1987 • 374 citations

Phosphorylation-induced mobility shift in phospholamban in sodium dodecyl sulfate-polyacrylamide gels. Evidence for a protein structure consisting of multiple identical phosphorylatable subunits.

1984 • 254 citations

Substrate specificity of a multifunctional calmodulin-dependent protein kinase.

1985 • 243 citations

Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban

1991 • 226 citations

The calcium and magnesium binding sites on cardiac troponin and their role in the regulation of myofibrillar adenosine triphosphatase.

1980 • 218 citations

Regulation of sarcoplasmic reticulum gene expression during cardiac and skeletal muscle development

1992 • 216 citations

Regulation of the Cardiac Ryanodine Receptor by Protein Kinase-Dependent Phosphorylation1

1991 • 199 citations

Relationships of molecular structure and function in Ca2(+)-transport ATPase

1990 • 191 citations

Effects of adenosine 3':5'-monophosphate-dependent protein kinase on sarcoplasmic reticulum isolated from cardiac and slow and fast contracting skeletal muscles.

1976 • 189 citations

Molecular mechanism of regulation of Ca2+ pump ATPase by phospholamban in cardiac sarcoplasmic reticulum. Effects of synthetic phospholamban peptides on Ca2+ pump ATPase.

1992 • 184 citations

Amino acids Glu2 to Ile18 in the cytoplasmic domain of phospholamban are essential for functional association with the Ca(2+)-ATPase of sarcoplasmic reticulum.

1994 • 166 citations

Effect of pH on ionic exchange and function in rat and rabbit myocardium

1975 • 165 citations

Phosphorylation and activation of the Ca(2+)-pumping ATPase of cardiac sarcoplasmic reticulum by Ca2+/calmodulin-dependent protein kinase.

1993 • 163 citations

Functional reconstitution of the cardiac sarcoplasmic reticulum Ca2(+)-ATPase with phospholamban in phospholipid vesicles.

1990 • 160 citations

Characterization of rabbit cardiac sarco(endo)plasmic reticulum Ca2(+)-ATPase gene.

1990 • 155 citations

Calmodulin modulation of single sarcoplasmic reticulum Ca2+-release channels from cardiac and skeletal muscle.

1989 • 150 citations

Effects of hypoxia on mechanics of cardiac contraction

1970 • 148 citations

Stimulation of bovine cardiac sarcoplasmic reticulum Ca2+ pump and blocking of phospholamban phosphorylation and dephosphorylation by a phospholamban monoclonal antibody.

1986 • 144 citations

Molecular tools to elucidate problems in excitation-contraction coupling

1990 • 140 citations

Effects of phospholamban phosphorylation catalyzed by adenosine 3′:5′-monophosphate- and calmodulin-dependent protein kinases on calcium transport ATPase of cardiac sarcoplasmic reticulum

1983 • 136 citations

Inactivation of the sarcoplasmic reticulum calcium channel by protein kinase

1992 • 124 citations

Possible control of intracellular calcium metabolism by [H+]: Sarcoplasmic reticulum of skeletal and cardiac muscle

1970 • 116 citations

Calmodulin-binding proteins from brain and other tissues

1979 • 98 citations

Incomplete Relaxation between Beats after Myocardial Hypoxia and Ischemia

1974 • 97 citations

Phospholamban expressed in slow-twitch and chronically stimulated fast-twitch muscles minimally affects calcium affinity of sarcoplasmic reticulum Ca(2+)-ATPase.

1992 • 95 citations

Differential alterations in ATP-supported calcium transport activities of sarcoplasmic reticulum and sarcolemma of aging myocardium

1981 • 92 citations

Proteolytic activation of the canine cardiac sarcoplasmic reticulum calcium pump

1986 • 91 citations

Age-related alterations in the phosphorylation of sarcoplasmic reticulum and myofibrillar proteins and diminished contractile response to isoproterenol in intact rat ventricle.

1993 • 88 citations

Phospholamban regulation of cardiac sarcoplasmic reticulum (Ca(2+)-Mg2+)-ATPase. Mechanism of regulation and site of monoclonal antibody interaction

1991 • 86 citations

Purification of the CaATPase of sarcoplasmic reticulum by affinity chromatography.

1984 • 82 citations

Rabbit cardiac and slow‐twitch muscle express the same phospholamban gene

1988 • 81 citations

Expression and characterization of the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II using the baculovirus expression system

1990 • 79 citations

[11] Regulation of Ca2+-pump from cardiac sarcoplasmic reticulum

1988 • 77 citations

Fluoroaluminate complexes are bifunctional analogues of phosphate in sarcoplasmic reticulum Ca(2+)-ATPase

1992 • 67 citations

Structural features of cation transport ATPases

1992 • 67 citations

Cardiac-specific phosphorylation site for multifunctional Ca2+/calmodulin-dependent protein kinase is conserved in the brain ryanodine receptor.

1992 • 66 citations

The effect of pH on the transient-state kinetics of Ca2+-Mg2+-ATPase of cardiac sarcoplasmic reticulum. A comparison with skeletal sarcoplasmic reticulum.

1982 • 66 citations

Fluoride is a slow, tight-binding inhibitor of the calcium ATPase of sarcoplasmic reticulum.

1992 • 62 citations

Characterization of structural unit of phospholamban by amino acid sequencing and electrophoretic analysis

1986 • 61 citations

Insulin action inhibits insulin-like growth factor-II (IGF-II) receptor phosphorylation in H-35 hepatoma cells. IGF-II receptors isolated from insulin-treated cells exhibit enhanced in vitro phosphorylation by casein kinase II.

1988 • 54 citations

Nucleotide triphosphate utilization by cardiac and skeletal muscle sarcoplasmic reticulum. Evidence for a hydrolysis cycle not coupled to intermediate acyl phosphate formation and calcium translocation.

1981 • 52 citations

Rapid purification of canine cardiac sarcoplasmic reticulum Ca2+-ATPase.

1978 • 48 citations

Use of aequorin for the appraisal of the hypothesis of the release of calcium from the sarcoplasmic reticulum induced by a change of pH in skinned cardiac cells

1985 • 47 citations

Inhibitory and stimulatory effects of fluoride on the calcium pump of cardiac sarcoplasmic reticulum

1991 • 39 citations

Effects of aging on phospholamban phosphorylation and calcium transport in rat cardiac sarcoplasmic reticulum

1990 • 37 citations

The binding of monoclonal and polyclonal antibodies to the Ca2+-ATPase of sarcoplasmic reticulum: effects on interactions between ATPase molecules

1990 • 36 citations

The role of phospholamban in the regulation of calcium transport by cardiac sarcoplasmic reticulum

1990 • 33 citations

Properties and characterization of a highly purified sarcoplasmic reticulum Ca2+-ATPase from dog cardiac and rabbit skeletal muscle.

1983 • 31 citations

Differential effects of non-ionic detergents on microsomal and sarcolemmal adenylate cyclase in cardiac muscle

1978 • 29 citations

Ion-motive ATPases : structure, function, and regulation

1992 • 29 citations

Expression of the internal calcium pump in pregnant rat uterus

1993 • 25 citations

Comparison of the effects of fluoride on the calcium pumps of cardiac and fast skeletal muscle sarcoplasmic reticulum: evidence for tissue-specific qualitative difference in calcium-induced pump conformation

1994 • 16 citations

Evidence for an effect of phospholamban on the regulatory role of ATP in calcium uptake by the calcium pump of the cardiac sarcoplasmic reticulum

1993 • 15 citations