Hydrogen peroxide increases GABAergic mIPSC through presynaptic release of calcium from IP₃ receptor‐sensitive stores in spinal cord substantia gelatinosa neurons

A TRP Channel that Senses Cold Stimuli and Menthol

2002 • 2,182 citations

Bell-shaped calcium-response curves of lns(l,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

1991 • 1,699 citations

Central sensitization and LTP: do pain and memory share similar mechanisms?

2003 • 1,406 citations

2APB, 2-Aminoethoxydiphenyl Borate, a Membrane-Penetrable Modulator of Ins(1,4,5)P3-Induced Ca2+ Release

1997 • 888 citations

Regulation of Phosphoinositide-specific Phospholipase C Isozymes

1997 • 866 citations

Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress.

1988 • 846 citations

2‐Aminoethoxydiphenyl borate (2‐APB) is a reliable blocker of store‐operated Ca²⁺entry but an inconsistent inhibitor of InsP₃‐induced Ca²⁺release

2002 • 678 citations

Local Calcium Signaling in Neurons

2003 • 601 citations

Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor

1996 • 457 citations

Reactive oxygen species (ROS) play an important role in a rat model of neuropathic pain

2004 • 444 citations

Presynaptic calcium stores underlie large-amplitude miniature IPSCs and spontaneous calcium transients

2000 • 394 citations

Measurement of striatal H2O2 by microdialysis following global forebrain ischemia and reperfusion in the rat: correlation with the cytotoxic potential of H2O2 in vitro

1995 • 333 citations

IP ₃ Receptor Types 2 and 3 Mediate Exocrine Secretion Underlying Energy Metabolism

2005 • 303 citations

Single-axon tracing study of neurons of the external segment of the globus pallidus in primate

2000 • 287 citations

A Specific Inhibitory Pathway between Substantia Gelatinosa Neurons Receiving Direct C-Fiber Input

2003 • 277 citations

2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels

2003 • 276 citations

Modulation of Transmitter Release by Presynaptic Resting Potential and Background Calcium Levels

2005 • 272 citations

Block of TRPC5 channels by 2‐aminoethoxydiphenyl borate: a differential, extracellular and voltage‐dependent effect

2005 • 250 citations

Gαi and Gαo are target proteins of reactive oxygen species

2000 • 244 citations

Blind patch-clamp recordings from substantia gelatinosa neurons in adult rat spinal cord slices: Pharmacological properties of synaptic currents

1993 • 236 citations

Effects of antagonists to high-threshold calcium channels upon spinal mechanisms of pain, hyperalgesia and allodynia

2000 • 234 citations

Stores Not Just for Storage

2001 • 223 citations

The role of the endoplasmic reticulum Ca2+ store in the plasticity of central neurons

2006 • 196 citations

Differential cellular expression of isoforms of inositol 1,4,5-triphosphate receptors in neurons and glia in brain

1999 • 193 citations

Induction of Hippocampal Long-Term Depression Requires Release of Ca²⁺from Separate Presynaptic and Postsynaptic Intracellular Stores

1996 • 189 citations

Physiological, neurochemical and morphological properties of a subgroup of GABAergic spinal lamina II neurones identified by expression of green fluorescent protein in mice

2004 • 185 citations

Hydrogen Peroxide Modulation of Synaptic Plasticity

2003 • 184 citations

The Role of TRP Channels in Oxidative Stress-induced Cell Death

2006 • 171 citations

Function and pharmacology of TRPM cation channels

2005 • 160 citations

Glutamate-Dependent Inhibition of Dopamine Release in Striatum Is Mediated by a New Diffusible Messenger, H₂O₂

2003 • 156 citations

Peripheral inflammation facilitates Abeta fiber-mediated synaptic input to the substantia gelatinosa of the adult rat spinal cord.

1999 • 152 citations

Presence and functional significance of presynaptic ryanodine receptors

2003 • 139 citations

Presynaptic calcium stores and synaptic transmission

2005 • 136 citations

Peripheral Inflammation Facilitates Aβ Fiber-Mediated Synaptic Input to the Substantia Gelatinosa of the Adult Rat Spinal Cord

1999 • 135 citations

The inositol triphosphate receptor family

1996 • 133 citations

Hydrogen Peroxide As a Diffusible Signal Molecule in Synaptic Plasticity

2004 • 131 citations

Menthol-Induced Ca²⁺Release from Presynaptic Ca²⁺Stores Potentiates Sensory Synaptic Transmission

2004 • 124 citations

The type 1 inositol 1,4,5-trisphosphate receptor gene is altered in the opisthotonos mouse.

1997 • 120 citations

Increase in External Glutamate and NMDA Receptor Activation Contribute to H₂O₂‐Induced Neuronal Apoptosis

1999 • 111 citations

Elevation of hydrogen peroxide after spinal cord injury detected by using the Fenton reaction

1999 • 107 citations

The Type 1 Inositol 1,4,5-Trisphosphate Receptor Gene Is Altered in theopisthotonosMouse

1997 • 101 citations

β3, a novel auxiliary subunit for the voltage‐gated sodium channel, is expressed preferentially in sensory neurons and is upregulated in the chronic constriction injury model of neuropathic pain

2000 • 95 citations

NMDA Receptor Activation Mediates Hydrogen Peroxide–Induced Pathophysiology in Rat Hippocampal Slices

2002 • 86 citations

Actions of brain‐derived neurotrophic factor on spinal nociceptive transmission during inflammation in the rat

2005 • 83 citations

Calcium Release from Presynaptic Ryanodine-Sensitive Stores Is Required for Long-Term Depression at Hippocampal CA3-CA3 Pyramidal Neuron Synapses

2004 • 78 citations

Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis

2005 • 78 citations

Wallerian degeneration and hyperalgesia after peripheral nerve injury are glutathione-dependent

1998 • 71 citations

Besides affecting intracellular calcium signaling, 2‐APB reversibly blocks gap junctional coupling in confluent monolayers, thereby allowing the measurement of single‐cell membrane currents in undissociated cells

2003 • 71 citations

Hydrogen peroxide modulates whole cell Ca2+ currents through L-type channels in cultured rat dentate granule cells

2004 • 69 citations

Cross talk between Ca²⁺and redox signalling cascades in muscle and neurons through the combined activation of ryanodine receptors/Ca²⁺release channels

2005 • 67 citations

Trigeminal pain transmission requires reactive oxygen species production

2005 • 62 citations

H2O2 regulates recombinant Ca2+ channel α1C subunits but does not mediate their sensitivity to acute hypoxia

2004 • 61 citations

Dual Action of Hydrogen Peroxide on Synaptic Transmission at the Frog Neuromuscular Junction

2003 • 56 citations

Measurement of the extracellular H2O2 in the brain by microdialysis

1998 • 56 citations

Phospholipase C-γ1 is required for cell survival in oxidative stress by protein kinase C

2002 • 51 citations

Phospholipase C-γ1 is required for cell survival in oxidative stress by protein kinase C

2002 • 39 citations

Pharmacological Modulation of Intracellular Ca<sup>2+</sup> Channels at the Single-Channel Level

2001 • 37 citations

Sustained l-type calcium currents in dissociated deep dorsal horn neurons of the rat: characteristics and modulation

2001 • 34 citations

Mechanism of antinociceptive effect of nimodipine in experimental diabetic neuropathic pain

2003 • 24 citations

Miniature postsynaptic currents depend on Ca2+ released from internal stores via PLC/IP3 pathway

2001 • 22 citations

Activation of purified cardiac ryanodine receptors by dihydropyridine agonists

2001 • 13 citations