Analysis of heat shock element recognition by saturation mutagenesis of the human HSP70.1 gene promoter.

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Heat shock proteins.

1990 • 1,365 citations

MECHANISM AND CONTROL OF TRANSCRIPTION INITIATION IN PROKARYOTES

1985 • 1,012 citations

Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions

1990 • 996 citations

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

1988 • 886 citations

Selection of DNA binding sites by regulatory proteins

1987 • 761 citations

Heat shock factor and the heat shock response

1991 • 615 citations

Is hsp70 the cellular thermometer?

1991 • 586 citations

Key features of heat shock regulatory elements.

1988 • 566 citations

Molecular cloning and expression of a human heat shock factor, HSF1.

1991 • 472 citations

Germline Transformation Used to Define Key Features of Heat-Shock Response Elements

1988 • 451 citations

Stable binding of Drosophila heat shock factor to head-to-head and tail-to-tail repeats of a conserved 5 bp recognition unit

1989 • 439 citations

Isolation of the gene encoding the S. cerevisiae heat shock transcription factor

1988 • 417 citations

Transcriptional control of rat heme oxygenase by heat shock.

1987 • 415 citations

Trimerization of a yeast transcriptional activator via a coiled-coil motif

1989 • 392 citations

Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability.

1991 • 381 citations

Molecular cloning and expression of a hexameric Drosophila heat shock factor subject to negative regulation

1990 • 375 citations

Selection of DNA binding sites by regulatory proteins

1988 • 364 citations

Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humans.

1991 • 347 citations

The DNA binding domain and bending angle of E. coli CAP protein

1986 • 322 citations

Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF.

1990 • 321 citations

Stress proteins in biology and medicine

1990 • 273 citations

Cooperative binding of drosophila heat shock factor to arrays of a conserved 5 bp unit

1991 • 250 citations

Mechanisms of Heat-Shock Gene Activation in Higher Eukaryotes

1987 • 240 citations

Nucleotide sequence and organization of the rat heme oxygenase gene.

1987 • 210 citations

Attenuation of the heat shock response in HeLa cells is mediated by the release of bound heat shock transcription factor and is modulated by changes in growth and in heat shock temperatures.

1991 • 197 citations

Specific recognition nucleotides and their DNA context determine the affinity of E2 protein for 17 binding sites in the BPV-1 genome.

1989 • 195 citations

Cloning and expression of a gene encoding hsc73, the major hsp70-like protein in unstressed rat cells.

1987 • 193 citations

Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a human hsp70 gene promoter.

1987 • 173 citations

Isolation and functional analysis of a human 70,000-dalton heat shock protein gene segment.

1985 • 164 citations

Cloning of random-sequence oligodeoxynucleotides

1986 • 162 citations

Heat shock-induced interactions of heat shock transcription factor and the human hsp70 promoter examined by in vivo footprinting.

1991 • 159 citations

Phenomenological Theory of Gel Electrophoresis of Protein-Nucleic Acid Complexes

1989 • 91 citations

Cis-acting elements involved in the regulated expression of a human hsp70 gene

1988 • 67 citations

Modular Recognition of 5-Base-Pair DNA Sequence Motifs by Human Heat Shock Transcription Factor

1991 • 25 citations