Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

1985 • 1,650 citations

Amino Acid Homology Between the Encephalitogenic Site of Myelin Basic Protein and Virus: Mechanism for Autoimmunity

1985 • 941 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination

1975 • 615 citations

Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells

1984 • 432 citations

Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice.

1989 • 372 citations

Lymphocyte specificity to protein antigens. I. Characterization of the antigen-induced in vitro T cell-dependent proliferative response with lymph node cells from primed mice.

1977 • 361 citations

Primary demyelination in Theiler's virus infection. An ultrastructural study.

1975 • 273 citations

Persistent infection of oligodendrocytes in Theiler's virus-induced encephalomyelitis

1983 • 243 citations

Molecular mimicry: frequency of reactivity of monoclonal antiviral antibodies with normal tissues

1986 • 243 citations

Theiler's Virus-Induced Demyelination: Prevention by Immunosuppression

1976 • 242 citations

Adoptive transfer of EAE-like lesions from rats with coronavirus-induced demyelinating encephalomyelitis

1983 • 233 citations

Statistical Methods in Research

1950 • 227 citations

Primary demyelination as a nonspecific consequence of a cell-mediated immune reaction.

1975 • 224 citations

Antibody responses in chronic relapsing experimental allergic encephalomyelitis: correlation of serum demyelinating activity with antibody titre to the myelin/oligodendrocyte glycoprotein (MOG)

1987 • 217 citations

The induction of cell-mediated immunity and tolerance with protein antigens coupled to syngeneic lymphoid cells.

1979 • 207 citations

Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in mice is influenced by the H-2D region: correlation with TEMV-specific delayed-type hypersensitivity.

1985 • 207 citations

Characterization of Theiler's murine encephalomyelitis virus (TMEV)-specific delayed-type hypersensitivity responses in TMEV-induced demyelinating disease: correlation with clinical signs.

1986 • 206 citations

Statistical Methods in Research.

1949 • 198 citations

Relapsing experimental allergic encephalomyelitis in the SJL/J mouse.

1981 • 197 citations

Susceptibility to Theiler's virus-induced demyelination. Mapping of the gene within the H-2D region.

1986 • 187 citations

Lymphocyte Specificity to Protein Antigens

1977 • 175 citations

Multiple Sclerosis as a Disease of Immune Regulation

1984 • 169 citations

Demyelination induced by Theiler's virus: influence of the H-2 haplotype.

1985 • 157 citations

The Effect of L3T4 T Cell Depletion on the Pathogenesis of Theiler's Murine Encephalomyelitis Virus Infection in CBA Mice

1987 • 155 citations

Mechanisms of regulation of cell-mediated immunity. II. Induction and suppression of delayed-type hypersensitivity to azobenzenearsonate-coupled syngeneic cells.

1978 • 146 citations

Two minor determinants of myelin basic protein induce experimental allergic encephalomyelitis in SJL/J mice.

1988 • 146 citations

Ultrastructural immunohistochemical localization of virus in acute and chronic demyelinating Theiler's virus infection.

1982 • 139 citations

Demyelinative myelopathy in mice induced by the DA virus

1976 • 139 citations

The induction of hapten-specific T cell tolerance by using hapten-modified lymphoid cells. I. Characteristics of tolerance induction.

1976 • 136 citations

Mechanisms of regulation of cell-mediated immune responses. I. Effect of the route of immunization with TNP-coupled syngeneic cells on the induction and suppression of contact sensitivity to picryl chloride.

1978 • 136 citations

Variations in genetic control of susceptibility to Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. I. Differences between susceptible SJL/J and resistant BALB/c strains map near the T cell beta-chain constant gene on chromosome 6.

1987 • 127 citations

Myelin basic protein and proteolipid protein reactivity of brain- and cerebrospinal fluid-derived T cell clones in multiple sclerosis and postinfectious encephalomyelitis.

1987 • 127 citations

The induction of hapten‐specific T cell tolerance using hapten‐modified lymphoid membranes II. Relative roles of suppressor T cells and clone inhibition in the tolerant state

1977 • 126 citations

Multiple sclerosis in the Faroe Islands.

1986 • 119 citations

Chronic neurologic disease in Theiler's virus infection of SJL/J mice

1976 • 108 citations

Partial suppression of Theiler's virus‐induced demyelination in vivo by administration of monoclonal antibodies to immune‐response gene products (Ia antigens)

1986 • 104 citations

Purification of Theiler's Murine Encephalomyelitis Virus and Analysis of the Structural Virion Polypeptides: Correlation of the Polypeptide Profile with Virulence

1980 • 101 citations

Theiler's virus antigen detected in mouse spinal cord 2½ years after infection

1984 • 99 citations

The Induction of Hapten-Specific T Cell Tolerance by Using Hapten-Modified Lymphoid Cells

1976 • 98 citations

The effect of short-term and chronic immunosuppression on Theiler's virus demyelination

1982 • 88 citations

Studies on the Species-Variability of Experimental Allergic Encephalomyelitis in Guinea Pigs and Rats

1974 • 87 citations

Virus-Induced Autoimmunity

1984 • 84 citations

Induction of autoimmune reactions to myelin basic protein in measles virus encephalitis in Lewis rats

1988 • 81 citations

Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. I. Cross-specificity among TMEV substrains and related picornaviruses, but not myelin proteins.

1987 • 81 citations

Monoclonal anti-I-A antibody reverses chronic paralysis and demyelination in Theiler's virus-infected mice: critical importance of timing of treatment

1987 • 70 citations

Specific immune regulation of chronic-relapsing experimental allergic encephalomyelitis in mice.

1988 • 69 citations

Mechanisms of Regulation of Cell-Mediated Immunity

1978 • 68 citations

Mechanisms of Regulation of Cell-Mediated Immune Responses

1978 • 59 citations

EPIDEMIOLOGY OF MULTIPLE SCLEROSIS: CRITIQUE OF THE EVIDENCE FOR A VIRAL ETIOLOGY

1978 • 48 citations

The Theiler's murine encephalomyelitis virus (TMEV) model for multiple sclerosis shows a strong influence of the murine equivalents of HLA-A, B, and C

1987 • 47 citations

ChemInform Abstract: Simultaneous Multiple Peptide Synthesis: The Rapid Preparation of Large Numbers of Discrete Peptides for Biological, Immunological, and Methodological Studies

1987 • 44 citations

Preparation of Proteolipids

1978 • 43 citations

Serum and cells from Theiler's virus-infected mice fail to injure myelinating cultures or to produce in vivo transfer of disease

1984 • 37 citations

Methods for the Identification and Characterization of Glycoproteins in Central and Peripheral Myelin

1985 • 37 citations

Simultaneous multiple peptide synthesis: The rapid preparation of large numbers of discrete peptides for biological, immunological, and methodological studies

1988 • 25 citations

IMMUNOCHEMICAL STUDIES OF ORGAN AND TUMOUR LIPIDS—XIV

1964 • 23 citations

Monoclonal antibody-induced inhibition of relapsing EAE in SJL/J mice correlates with inhibition of neuroantigen-specific cell-mediated immune responses☆

1987 • 20 citations

The pathogenetic significance of cross reactions in autoimmune disease of the nervous system

1984 • 15 citations

A rapid method for quantitation of antiviral antibodies

1989 • 10 citations

Theiler's virus encephalomyelitis is unaffected by treatment with myelin components

1985 • 7 citations