Crystallization studies of cAMP-dependent protein kinase

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Solvent content of protein crystals

1968 • 7,954 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

Regulation and Kinetics of the Actin-Myosin-ATP Interaction

1980 • 1,077 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

The distribution and dissociation of cyclic adenosine 3':5'-monophosphate-dependent protein kinases in adipose, cardiac, and other tissues.

1975 • 758 citations

A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase.

1986 • 581 citations

Peptides and Protein Phosphorylation

2018 • 525 citations

Casein Kinases—Multipotential Protein Kinases

1982 • 454 citations

Expression Cloning of Human EGF Receptor Complementary DNA: Gene Amplification and Three Related Messenger RNA Products in A431 Cells

1984 • 406 citations

Regulatory Mechanisms in the Control of Protein Kinase

1982 • 357 citations

The Role of Cyclic-AMP-Dependent Protein Kinase in the Regulation of Glycogen Metabolism in Mammalian Skeletal Muscle

1978 • 352 citations

Direct evidence that oncogenic tyrosine kinases and cyclic AMP-dependent protein kinase have homologous ATP-binding sites

1984 • 345 citations

Glucose-induced conformational change in yeast hexokinase.

1978 • 305 citations

Space-Filling Models of Kinase Clefts and Conformation Changes

1979 • 280 citations

cAMP-dependent Protein Kinase

1989 • 274 citations

Characterization of a tyrosine-specific kinase activity in human fibroblast membranes stimulated by platelet-derived growth factor.

1982 • 253 citations

Space-Filling Models of Kinase Clefts and Conformation Changes: Comparison of the surface structures of kinase enzymes implicates closing clefts in their mechanism.

1979 • 223 citations

Structure of Yeast Phosphoglycerate Kinase

1974 • 222 citations

Affinity labeling of cAMP-dependent protein kinase with p-fluorosulfonylbenzoyl adenosine. Covalent modification of lysine 71.

1981 • 191 citations

Structure of horse muscle phosphoglycerate kinase

1974 • 189 citations

Homology of the .gamma. subunit of phosphorylase b kinase with cAMP-dependent protein kinase

1984 • 173 citations

Substrate binding closes the cleft between the domains of yeast phosphoglycerate kinase.

1979 • 173 citations

Structure and control of phosphofructokinase from Bacillus stearothermophilus

1979 • 172 citations

On the relative scaling of X-ray photographs

1965 • 154 citations

The phosphorylation of proteins: a major mechanism for biological regulation

1985 • 151 citations

Distinction between “Self” and “Not-Self” in Lower Invertebrates

1970 • 143 citations

Effect of denaturation on the susceptibility of proteins to enzymic phosphorylation

1975 • 135 citations

Yeast hexokinase in solution exhibits a large conformational change upon binding glucose or glucose 6-phosphate

1979 • 129 citations

Strategy for data collection from protein crystals using a multiwire counter area detector diffractometer

1985 • 114 citations

cAMP‐dependent protein kinase: prototype for a family of enzymes

1988 • 99 citations

Modification of the catalytic subunit of bovine heart cAMP-dependent protein kinase with affinity labels related to peptide substrates.

1982 • 95 citations

Nuclear‐Magnetic‐Resonance Study of the Active‐Site Structure of Yeast Phosphoglycerate Kinase

1976 • 93 citations

Magnetic resonance studies of the effect of the regulatory subunit on metal and substrate binding to the catalytic subunit of bovine heart protein kinase.

1980 • 82 citations

Differential labeling and identification of the cysteine-containing tryptic peptides of catalytic subunit from porcine heart cAMP-dependent protein kinase.

1981 • 81 citations

Structure of pyruvate kinase and similarities with other enzymes: possible implications for protein taxonomy and evolution

1978 • 81 citations

The structure of a yeast hexokinase monomer and its complexes with substrates at 2.7-A resolution.

1975 • 80 citations

The electron stationary picture method for high-speed measurement of reflection intensities from crystals with large unit cells

1978 • 78 citations

Properties of a CH3-blocked creatine kinase with altered catalytic activity. Kinetic consequences of the presence of the blocking group.

1977 • 75 citations

Interaction of Manganous Ion, Substrates, and Anions with Arginine Kinase

1974 • 60 citations

Structure of yeast hexokinase

1973 • 58 citations

Selective protection of sulfhydryl groups in cAMP-dependent protein kinase II.

1983 • 56 citations

Salt-induced conformational changes in the catalytic subunit of adenosine 3',5'-phosphate dependent protein kinase. Use for establishing a connection between one sulfhydryl group and the .gamma.-P subsite in the ATP site of this subunit

1982 • 52 citations

Structure of Horse-muscle Phosphoglycerate Kinase at 6 Å Resolution

1972 • 52 citations

X-ray grade crystals of diphtheria toxin.

1982 • 50 citations

Studies of the mechanism of action and regulation of cAMP-dependent protein kinase

1980 • 49 citations

Protein kinases: A diverse family of related proteins

1987 • 46 citations

Yeast hexokinase PII. Conformational changes induced by substrates and substrate analogues.

1978 • 42 citations

Use of the multiwire area detector diffractometer as a national resource for protein crystallography

1985 • 39 citations

Low resolution structure of adenylate kinase

1973 • 39 citations

Structure of yeast hexokinase-B

1971 • 37 citations

Crystallization studies of cAMP-dependent protein kinase

1985 • 32 citations

cAMP-dependent Protein Kinase: A Framework for a Diverse Family of Enzymes

1988 • 31 citations

Adenosine cyclic 3',5'-phosphate-dependent protein kinase from bovine brain: inactivation of the catalytic subunit and holoenzyme by 7-chloro-4-nitro-2,1,3-benzoxadiazole

1982 • 29 citations

Tyrosine kinase catalyzed phosphorylation and inactivation of the inhibitor protein of the cAMP-dependent protein kinase.

1987 • 28 citations

X-Ray Small-Angle Scattering of the Allosteric Yeast Pyruvate Kinase

1972 • 28 citations

Crystallization of a tryptic core of the single-stranded DNA binding protein of bacteriophage T4

1982 • 10 citations

たんぱく質結晶学に対する国家共同装置(national resource)としてのマルチワイヤ二次元検出回折計の利用

1985 • 9 citations