The Role of Cyclic-AMP-Dependent Protein Kinase in the Regulation of Glycogen Metabolism in Mammalian Skeletal Muscle

An Adenosine 3′,5′-Monophosphate-dependant Protein Kinase from Rabbit Skeletal Muscle

1968 • 1,423 citations

FRACTIONATION AND CHARACTERIZATION OF A CYCLIC ADENINE RIBONUCLEOTIDE FORMED BY TISSUE PARTICLES

1958 • 1,055 citations

Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase.

1977 • 844 citations

Purification and Properties of Rabbit Skeletal Muscle Adenosine 3',5'-Monophosphate-dependent Protein Kinases

1971 • 810 citations

The Subunit Structure of Rabbit‐Skeletal‐Muscle Phosphorylase Kinase, and the Molecular Basis of Its Activation Reactions

1973 • 727 citations

Purification and Properties of Rabbit Skeletal Muscle Phosphorylase b Kinase^*

1964 • 545 citations

A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors

1972 • 524 citations

THE RELATIONSHIP OF EPINEPHRINE AND GLUCAGON TO LIVER PHOSPHORYLASE

1957 • 486 citations

The phosphorylase b to a converting enzyme of rabbit skeletal muscle

1956 • 463 citations

Separation and Characterization of Two Phosphorylase Phosphatase Inhibitors from Rabbit Skeletal Muscle

1976 • 439 citations

Glycogen Synthetase Activity in Skeletal Muscle

1965 • 436 citations

Factors Affecting the Activity of Muscle Phosphorylase b Kinase

1959 • 418 citations

The Regulation of Skeletal Muscle Phosphorylase Kinase by Ca2+

1971 • 416 citations

Inactivation of Glycogen Synthetase and Activation of Phosphorylase Kinase by Muscle Adenosine 3',5'-Monophosphate-dependent Protein Kinases

1970 • 410 citations

Complete Amino-Acid Sequence of Actin of Rabbit Skeletal Muscle

1973 • 396 citations

Control of Phosphorylase Activity in a Muscle Glycogen Particle

1970 • 358 citations

Ancient Linkage Groups and Frozen Accidents

1973 • 338 citations

Activation of Skeletal Muscle Phosphorylase Kinase by Adenosine Triphosphate and Adenosine 3′,5′-Monophosphate

1968 • 329 citations

Studies on UDPG-α-Glucan Transglucosylase. III. Interconversion of Two Forms of Muscle UDPG-α-Glucan Transglucosylase by a Phosphorylation-Dephosphorylation Reaction Sequence^*

1963 • 310 citations

Binding of Glycolytic Enzymes to Structure Proteins of the Muscle

1968 • 299 citations

The Regulation of Glycogen Metaabolism

1978 • 297 citations

Catalysis of the Phosphorylase Kinase Activation Reaction

1971 • 294 citations

Isolation and properties of the rabbit skeletal muscle protein inhibitor of adenosine 3',5'-monophosphate dependent protein kinases

1977 • 264 citations

Control of Phosphorylase Activity in a Muscle Glycogen Particle

1970 • 244 citations

Activation of skeletal muscle phosphorylase kinase by calcium ions. II. Identification of the kinase activating factor as a proteolytic enzyme

1968 • 238 citations

Complete amino acid sequence of rabbit muscle glycogen phosphorylase.

1977 • 229 citations

Phosphorylation of troponin and the effects of interactions between the components of the complex

1974 • 228 citations

The minimum substrate of cyclic AMP-stimulated protein kinase, as studied by synthetic peptides representing the phosphorylatable site of pyruvate kinase (type L) of rat liver

1976 • 214 citations

Effects of Electrical Stimulation and Epinephrine on Muscle Phosphorylase, Phosphorylase b Kinase, and Adenosine 3‘,5‘-Phosphate

1965 • 211 citations

Glycogen Synthetase-D Phosphatase

1972 • 200 citations

Insulin-mediated effect on the activity of UDPG-glycogen transglucosylase of muscle

1960 • 200 citations

The Purification and Properties of Rabbit Skeletal Muscle Glycogen Synthase

1976 • 196 citations

Structure of the Site Phosphorylated in the Phosphorylase b to a Reaction

1959 • 194 citations

Comparison of the substrate specificities of protein phosphatases involved in the regulation of glycogen metabolism in rabbit skeletal muscle

1977 • 193 citations

Subunit structure of rabbit skeletal muscle phosphorylase kinase

1973 • 187 citations

UDP-glucose: glycogen α-4-glucosyltransferase I kinase activity of purified muscle protein kinase

1969 • 171 citations

Physicochemical properties of rabbit skeletal muscle phosphorylase kinase

1973 • 169 citations

Insulin treatment and increased UDPG-glycogen transglucosylase activity in muscle

1961 • 165 citations

INTRACELLULAR LOCALIZATION OF GLYCOGENOLYTIC AND GLYCOLYTIC ENZYMES IN WHITE AND RED RABBIT SKELETAL MUSCLE A GEL FILM METHOD FOR COUPLED ENZYME REACTIONS IN HISTOCHEMISTRY

1969 • 163 citations

Studies on the Activation of Phosphorylase in Skeletal Muscle by Contraction and by Epinephrine

1969 • 163 citations

Regulation of muscle glycogen synthetase by metabolites. Differential effects on the I and D forms

1968 • 149 citations

The phosphorylation of troponin I from cardiac muscle

1975 • 148 citations

RABBIT SKELETAL MUSCLE GLYCOGEN

1968 • 145 citations

The substrate specificity of adenosine 3′:5′-cyclic monophosphate-dependent protein kinase of rabbit skeletal muscle

1977 • 142 citations

In vivo regulation of rat muscle glycogen synthetase activity

1969 • 137 citations

Effect of denaturation on the susceptibility of proteins to enzymic phosphorylation

1975 • 135 citations

CYCLIC AMP AND HISTONE PHOSPHORYLATION*

1971 • 130 citations

Protein Kinases: Aspects of Their Regulation and Diversity

1973 • 129 citations

Influence Of Epinephrine and Insulin on Uridine Diphosphate Glucose-α-Glucan Transferase and Phosphorylase in Muscle

1964 • 127 citations

Properties of a Phosphoprotein Phosphatase from Bovine Heart with Activity on Glycogen Synthase, Phosphorylase, and Histone

1974 • 126 citations

Quantitative Comparison of the Binding of Various Glycolytic Enzymes to F‐Actin and the Interaction of Aldolase with G‐Actin

1971 • 126 citations

Phosphorylation of the Inhibitor Component of Troponin by Phosphorylase Kinase

1972 • 125 citations

The Rigulation of Glycogen Metabolism

1978 • 124 citations

A protein inhibitor of rabbit liver phosphorylase phosphatase

1975 • 121 citations

Debranching Enzyme from Rabbit Skeletal Muscle

1975 • 120 citations

The Phosphorylation of Rabbit Skeletal Muscle Glycogen Synthase by Glycogen Synthase Kinase-2 and Adenosine-3': 5'-Monophosphate-Dependent Protein Kinase

1976 • 118 citations

Regulation of glycogen synthase. Phosphorylation specificities of cAMP-dependent and cAMP-independent kinases for skeletal muscle synthase.

1977 • 116 citations

The Hormonal Control of Activity of Skeletal Muscle Phosphorylase Kinase

1975 • 116 citations

Separation of Two Phosphorylase Kinase Phosphatases from Rabbit Skeletal Muscle

1976 • 115 citations

Specificity of a protein phosphatase inhibitor from rabbit skeletal muscle

1977 • 114 citations

Glycogen synthetase kinase 2 (GSK 2); The identification of a new protein kinase in skeletal muscle

1974 • 112 citations

Amino acid sequences at the two sites on glycogen synthetase phosphorylated by cyclic AMP‐dependent protein kinase and their dephosphorylation by protein phosphatase‐III

1977 • 111 citations

The hormonal control of glycogen metabolism: The amino acid sequence at the phosphorylation site of protein phosphatase inhibitor‐1

1977 • 107 citations

Glycogenolysis during Tetanic Contraction of Isolated Mouse Muscles in the Presence and Absence of Phosphorylase a

1964 • 107 citations

The Hormonal Control of Activity of Skeletal Muscle Phosphorylase Kinase

1975 • 107 citations

A study on the autoactivation of rabbit muscle phosphorylase kinase.

1976 • 103 citations

X‐Linked testicular feminization in the mouse as a non‐inducible regulatory mutation of the Jacob‐Monod type

1970 • 103 citations

THE ACTION OF NUCLEOTIDES IN THE DISRUPTIVE PHOSPHORYLATION OF GLYCOGEN

1938 • 102 citations

Structural studies on rabbit muscle glycogen synthase. I. Subunit composition

1975 • 98 citations

Studies on the Phosphorylation and Activation of Skeletal Muscle Phosphorylase and Phosphorylase Kinase in Vivo

1970 • 95 citations

Regulation of glycogen synthetase. Specificity and stoichiometry of phosphorylation of the skeletal muscle enzyme by cyclic 3':5'-AMP-dependent protein kinase.

1975 • 88 citations

Molecular characteristics of the totally dependent and independent forms of glycogen synthase of rabbit skeletal muscle

1971 • 88 citations

The amino acid sequence of rabbit cardiac troponin I

1976 • 87 citations

Multiple forms of phosphorylase kinase in red and white skeletal muscle

1974 • 81 citations

The control of phosphorylase kinase phosphatase by “second site phosphorylation”; A new form of enzyme regulation

1973 • 81 citations

Activation of glycogen synthetase and inactivation of phosphorylase kinase by the same phosphoprotein phosphatase

1973 • 79 citations

Calsequestrin, Myosin, and the Components of the Protein‐Glycogen Complex in Rabbit Skeletal Muscle

1978 • 76 citations

A second heat‐stable protein inhibitor of phosphorylase phosphatase from rabbit muscle

1976 • 76 citations

Total conversion of glycogen synthase from the I- to the D-form by a cyclic AMP-independent protein kinase from rabbit skeletal muscle.

1977 • 72 citations

Glycogen synthase kinases. Distribution in mammalian tissues of forms that are independent of cyclic AMP.

1977 • 67 citations

Studies on UDPG: α-1,4-Glucan α-4-Glucosyltransferase. VI. Specificity and Structural Requirements for the Activator of the D Form of the Dog Muscle Enzyme^*

1964 • 65 citations

Non-dependence on native structure of pig liver pyruvate kinase when used as a substrate for cyclic 3′,5′-AMP-stimulated protein kinase

1975 • 63 citations

Structural studies on rabbit muscle glycogen synthase. II. Limited proteolysis

1975 • 60 citations

Regulation of glycogen synthetase activity by two kinases

1975 • 60 citations

Control of Enzyme Activity

1983 • 58 citations

Amino acid sequence of a phosphorylation site in skeletal muscle glycogen synthetase

1977 • 58 citations

The substrate specificity of cyclic AMP‐dependent protein kinase: Amino acid sequences at the phosphorylation sites of herring protamine (clupeine)

1978 • 57 citations

The Molecular Basis of Skeletal Muscle Phosphorylase Kinase Deficiency

1976 • 56 citations

The sites of phosphorylation of rabbit cardiac troponin I by adenosine 3′:5′-cyclic monophosphate-dependent protein kinase. Effect of interaction with troponin C

1977 • 55 citations

The X-chromosome and the enzymes controlling muscle glycogen: Phosphorylase kinase

1970 • 54 citations

Effect of Mg2+ concentration on the cAMP-dependent protein kinase-catalyzed activation of rabbit skeletal muscle phosphorylase kinase.

1977 • 54 citations

Regulation of glycogen synthetase. Effects of trypsin on the structure, activity, and phosphorylation of the skeletal muscle enzyme.

1976 • 53 citations

Muscle glycogen synthase in vivo state:

1977 • 53 citations

Activation of glycogen phosphorylase kinase by a calcium-activated, cyclic nucleotide-independent protein kinase system.

1977 • 52 citations

The role of phosphorylase kinase in the nervous and hormonal control of glycogenolysis in muscle.

1974 • 52 citations

Amino acid sequence at the phosphorylated site of rat liver pyruvate kinase

1975 • 50 citations

Isolation of a glycogen synthase I kinase that is independent of adenosine 3':5'-monophosphate.

1975 • 50 citations

Amino‐terminal sequence of rabbit muscle phosphorylase

1975 • 50 citations

Hormonal and non-hormonal control of glycogen synthesis — Control of transferase phosphatase and transferase I kinase

1968 • 47 citations

Substrate Specificity of Hexokinases

1961 • 47 citations

Distribution of isoenzymes of the glycogenolytic cascade in different types of muscle fibre

1976 • 46 citations

Substrate specificity of glycogen synthase phosphatase from bovine heart: Action on phosphorylase a and histone

1973 • 46 citations

Subunit structure of trypsin-activated phosphorylase kinase

1973 • 45 citations

Peptides from myelin basic protein as substrates for adenosine 3′, 5′-cyclic monophosphate-dependent protein kinases

1974 • 44 citations

Control of Enzyme Activity

1976 • 43 citations

CYCLIC AMP IN SKELETAL MUSCLE*

1971 • 36 citations

Skeletal muscle phosphorylase kinase deficiency: Detection of a protein lacking any activity in ICR/IAn mice

1973 • 35 citations

Characterization of a Ca2+-Dependent Protein Kinase in Skeletal Muscle Membranes of I-Strain and Wild-Type Mice

1978 • 34 citations

Characterization of the Phosphorylase b to a Converting Activity in Skeletal Muscle Extracts of Mice with the Phosphorylase b Kinase Deficiency Mutation

1974 • 32 citations

Skeletal muscle purine nucleotide levels in normal and phosphorylase kinase deficient mice

1976 • 26 citations

Phosphorylation of the inhibitory subunit of troponin in perfused hearts of mice deficient in phosphorylase kinase. Evidence for the phosphorylation of troponin by adenosine 3′:5′-phosphate-dependent protein kinase in vivo

1977 • 25 citations

Glycogen-storage disease associated with phosphorylase kinase deficiency: evidence for X inactivation.

1974 • 24 citations

Is Phosphorylase Phosphatase a Manganese Metalloenzyme?

1978 • 23 citations

Effect of limited proteolysis on activity and phosphorylation of rabbit muscle glycogen synthetase

1976 • 22 citations

The substrate specificity and regulation of the protein phosphatases involved in the control of glycogen metabolism in mammalian skeletal muscle

1978 • 19 citations

Structure and Regulation of Enzymes for the Degradation and Resynthesis of Glycogen

1975 • 18 citations

Activity of rat‐liver phosphoprotein phosphatase on phosphopeptides formed in the cyclic AMP‐dependent protein kinase reaction

1977 • 14 citations

Postnatal development of phosphorylase kinase in mouse skeletal muscle

1977 • 11 citations