In vitro Approach to Development of Immune Reactivity

Plaque Formation in Agar by Single Antibody-Producing Cells

1963 • 2,385 citations

Further improvements in the plaque technique for detecting single antibody-forming cells.

1968 • 2,171 citations

IMMUNIZATION OF DISSOCIATED SPLEEN CELL CULTURES FROM NORMAL MICE

1967 • 2,062 citations

THE GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

1966 • 1,944 citations

THE ORIGIN AND KINETICS OF MONONUCLEAR PHAGOCYTES

1968 • 1,492 citations

Phytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes.

1960 • 1,394 citations

Ontogeny of the Haemopoietic System: Yolk Sac Origin of In Vivo and In Vitro Colony Forming Cells in the Developing Mouse Embryo*

1970 • 1,031 citations

THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES

1964 • 1,030 citations

The cloning of normal “Mast” cells in tissue culture

1965 • 886 citations

Infectious immunological tolerance.

1971 • 811 citations

The culture of mature organs in a synthetic medium

1959 • 773 citations

The Bursa of Fabricius and Antibody Production

1956 • 701 citations

The carrier effect in the secondary response to hapten‐protein conjugates. II. Cellular cooperation

1971 • 677 citations

CELL TO CELL INTERACTION IN THE IMMUNE RESPONSE

1968 • 668 citations

IMMUNOGLOBULINS ON THE SURFACE OF LYMPHOCYTES

1971 • 665 citations

CELL TO CELL INTERACTION IN THE IMMUNE RESPONSE

1968 • 639 citations

A Requirement for Two Cell Types for Antibody Formation in vitro

1967 • 612 citations

T Cell Control of Antibody Production

1974 • 582 citations

Current concepts of the immunological function of the thymus.

1967 • 577 citations

Progress in immunology

1968 • 577 citations

Replacement of T-Cell Function by a T-Cell Product

1972 • 537 citations

One-Way Stimulation in Mixed Leukocyte Cultures

1966 • 534 citations

Trans-filter induction of tubules in mouse metanephrogenic mesenchyme

1956 • 521 citations

Lymphocyte Interaction: A Potential Histocompatibility Test in vitro

1964 • 510 citations

EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS

1967 • 504 citations

Developmental aspects of antibody formation and structure

1972 • 466 citations

Theta Isoantigen as a Marker of Thymus-derived Lymphocytes in Mice

1969 • 449 citations

ANTIBODY FORMATION IN VITRO

1961 • 445 citations

Induction of immunoglobulin and antibody synthesis in vitro by lipopolysaccharides

1972 • 431 citations

Suppressor T cells.

1972 • 430 citations

Immune responses in vitro. I. Culture conditions for antibody synthesis

1972 • 426 citations

Selective induction of DNA synthesis in T and B lymphocytes

1972 • 411 citations

Contemporary Topics in Immunobiology

1977 • 410 citations

Epitheliomesenchymal interaction in pancreatic morphogenesis

1962 • 409 citations

PRIMARY IMMUNE RESPONSE IN CULTURES OF SPLEEN CELLS

1967 • 397 citations

Toward Molecular Mechanisms of Developmental Processes

1973 • 384 citations

A Method of Increased Sensitivity for detecting Single Antibody-forming Cells

1965 • 381 citations

ANTIBODY FORMATION INITIATED IN VITRO

1963 • 360 citations

The induction of clones of normal mast cells by a substance from conditioned medium

1966 • 358 citations

Thymus and Antigen‐Reactive Cells

1969 • 345 citations

Morphogenetic interactions in the development of the mouse thymus gland

1960 • 336 citations

Immunogenicity of Antigen-Containing Ribonucleic Acid Preparations from Macrophages

1965 • 323 citations

Activation of T and B Lymphocytes by Insoluble Phytomitogens

1972 • 318 citations

Purification and Biological Activity of Thymosin, a Hormone of the Thymus Gland

1972 • 308 citations

TISSUE INTERACTION IN THE DEVELOPMENT OF THYMUS LYMPHOCYTES

1969 • 295 citations

Surface Antigenic Markers for Distinguishing T and B Lymphocytes in Mice

1971 • 295 citations

ISOLATION, BIOCHEMICAL CHARACTERISTICS, AND BIOLOGICAL ACTIVITY OF A CIRCULATING THYMIC HORMONE IN THE MOUSE AND IN THE HUMAN

1975 • 288 citations

Evidence for thymus-independent humoral antibody production in mice against polyvinylpyrrolidone and E. coli lipopolysaccharide

1971 • 280 citations

Mouse Thymic Iso-antigens

1966 • 278 citations

IMMUNOGLOBULINS ON THE SURFACE OF LYMPHOCYTES

1971 • 276 citations

THE MECHANISM OF ANTIGENIC STIMULATION OF PRIMARY AND SECONDARY CLONAL PRECURSOR CELLS

1972 • 272 citations

THE EFFECTS OF MERCAPTOETHANOL AND OF PERITONEAL MACROPHAGES ON THE ANTIBODY-FORMING CAPACITY OF NONADHERENT MOUSE SPLEEN CELLS IN VITRO

1972 • 267 citations

Studies of allograft immunity in mice. I. Induction, development and in vitro assay of cellular immunity.

1970 • 266 citations

CARRIER FUNCTION IN ANTI-HAPTEN IMMUNE RESPONSES

1970 • 265 citations

FETAL RESPONSE TO ANTIGENIC STIMULUS

1963 • 261 citations

Functional heterogeneity of murine lymphoid cells. 3. Differential responsiveness of T cells to phytohemagglutinin and concanavalin A as a probe for T cell subsets.

1973 • 259 citations

Mitogens as Probes for Immunocyte Activation and Cellular Cooperation

1972 • 256 citations

Elicitation of Selective T and B Lymphocyte Responses by Cell Surface Binding Ligands

1972 • 253 citations

DIFFERENTIATION OF T CELLS INDUCED BY PREPARATIONS FROM THYMUS AND BY NONTHYMIC AGENTS

1973 • 252 citations

THE MITOTIC RESPONSE OF THYMUS-DERIVED CELLS TO ANTIGENIC STIMULUS

1966 • 246 citations

Requirement of Thymus-dependent Lymphocytes for Potentiation by Adjuvants of Antibody Formation

1971 • 245 citations

Immunologic Complementation between Thymus and Marrow Cells—A Model for the Two‐Cell Theory of Immunocompetence

1969 • 240 citations

SYNERGY AMONG LYMPHOID CELLS MEDIATING THE GRAFT-VERSUS-HOST RESPONSE

1972 • 240 citations

Antigen-induced selective recruitment of circulating lymphocytes

1971 • 239 citations

A THREE-CELL INTERACTION REQUIRED FOR THE INDUCTION OF THE PRIMARY IMMUNE RESPONSE in vitro

1968 • 237 citations

Suppression of Immunoglobulin G Synthesis as a Result of Antibody-Mediated Suppression of Immunoglobulin M Synthesis in Chickens

1970 • 235 citations

THE FAILURE OF THYMUS-DERIVED CELLS TO PRODUCE ANTIBODY

1967 • 233 citations

Stimulation of B-lymphocytes by endotoxin. Reactions of thymus-deprived mice and karyotypic analysis of dividing cells in mice bearing T 6 T 6 thymus grafts.

1972 • 232 citations

Mixed Lymphocyte Cultures Produce Effector Cells: Model in vitro for Allograft Rejection

1970 • 230 citations

Immunization of Normal Mouse Spleen Cell Suspensions in vitro

1966 • 230 citations

TISSUE GRAFTING AND RADIATION

1967 • 225 citations

Experimental analysis of the origin of cell types in the development of the mouse thymus

1961 • 224 citations

Origin and kinetics of monocytes and macrophages.

1970 • 223 citations

A Localized Haemolysis in Gel Method for the Detection of Cells Producing 7S Antibody: Detection of Cells producing 7S Antibodies by the Plaque Technique

1965 • 223 citations

Mechanism of Antibody Diversity: Germ Line Basis for Variability

1970 • 222 citations

Ontogeny of mouse lymphocyte function. II. Development of the ability to produce antibody is modulated by T lymphocytes.

1975 • 220 citations

A Modification of the Hemolytic Plaque Assay for Use with Protein Antigens

1968 • 219 citations

Chromosome Marker Studies on the Development of the Haemopoietic System in the Chick Embryo

1965 • 216 citations

In vitro Cytotoxic Activity of Thymus Cells sensitized to Alloantigens

1970 • 216 citations

Cellular Control Mechanisms and Cancer.

1965 • 211 citations

The role of macrophages in the induction of antibody in x-irradiated animals.

1967 • 211 citations

In vitro generation of B lymphocytes in mouse foetal liver, a mammalian ‘bursa equivalent’

1974 • 210 citations

Tolerance, Enhancement and the Regulation of Interactions Between T Cells, B Cells and Macrophages

1972 • 208 citations

Origin and Turnover of Monocytes and Macrophages

1989 • 200 citations

STUDIES ON THE DIFFERENTIATION OF THYMUS-DERIVED LYMPHOCYTES

1970 • 198 citations

Appearance of T-cell Markers in Bone Marrow Rosette-Forming Cells after Incubation with Thymosin, a Thymic Hormone

1971 • 195 citations

A Simple Method for detecting Single Antibody-forming Cells

1964 • 188 citations

The Thymus and the Cellular Basis of Immunity

1969 • 188 citations

Interrelationships of myeloid and lymphoid cells: studies with chromosome-marked cells transfused into lethally irradiated mice

1966 • 186 citations

STEM-CELL MIGRATION IN DEVELOPING MYELOID AND LYMPHOID SYSTEMS

1967 • 183 citations

CELL-MEDIATED IMMUNE RESPONSE IN VITRO

1972 • 180 citations

General methods for the study of cells and serum during the immune response: the response to dinitrophenyl in mice.

1969 • 179 citations

An in Vitro Primary Immune Response to 2, 4, 6-Trinitrophenyl Substituted Erythrocytes: Response against Carrier and Hapten

1970 • 178 citations

Lymphocyte activation. II. discriminating stimulation of lymphocyte subpopulations by phytomitogens and heterologous antilymphocyte sera.

1972 • 178 citations

Evidence for Individual Human Peripheral Blood Lymphocytes bearing both B and T Cell Markers

1974 • 175 citations

Selection of a Single Antibody-Forming Cell Clone and Its Propagation in Syngeneic Mice

1970 • 175 citations

Immune responses in vitro

1972 • 168 citations

Thymus-dependent and thymus-independent populations: origin, migratory patterns and lifespan.

1971 • 166 citations

CELL INTERACTIONS IN THE PRIMARY IMMUNE RESPONSE IN VITRO: A REQUIREMENT FOR SPECIFIC CELL CLUSTERS

1969 • 165 citations

CELL INTERACTIONS IN THE IMMUNE RESPONSE IN VITRO

1972 • 162 citations

APPLICATION OF A LOCALIZED HEMOLYSIN REACTION FOR SPECIFIC DETECTION OF INDIVIDUAL ANTIBODY-FORMING CELLS

1964 • 162 citations

Induction in vitro of Antibodies to Phage T2: Antigens in the RNA Extract Employed

1965 • 159 citations

T cell factor which can replace T cells in vivo

1974 • 156 citations

Experimental studies on the development of the bursa of Fabricius

1966 • 156 citations

Induction of antibody‐forming cell clones in microcultures

1972 • 155 citations

General Method for the Detection of Cells producing Antibodies against Haptens and Proteins

1970 • 155 citations

CELL INTERACTIONS IN THE IMMUNE RESPONSE IN VITRO

1972 • 155 citations

CELL INTERACTIONS IN THE IMMUNE RESPONSE IN VITRO

1972 • 153 citations

Aspects of Synthesis and Order in Growth

1956 • 152 citations

ROLE OF MACROPHAGES IN IMMUNOLOGICAL MATURATION

1968 • 151 citations

Strain differences in the immune response of mice. I. The neonatal response to sheep red cells.

1968 • 150 citations

Foetal and neonatal immunology

1971 • 149 citations

Aspects of synthesis and order in growth

1954 • 147 citations

A MAMMALIAN EQUIVALENT OF THE AVIAN BURSA OF FABRICIUS

1966 • 146 citations

CHARACTERIZATION OF SPLENIC LYMPHOID CELLS IN FETAL AND NEWBORN MICE

1973 • 143 citations

Lipopolysaccharide can substitute for helper cells in the antibody response in vitro

1972 • 143 citations

Regulation of lymphocyte responses in vitro. 3. Inhibition by adherent cells of the T-lymphocyte response to phytohemagglutinin.

1973 • 141 citations

Functional Heterogeneity of Murine Lymphoid Cells

1973 • 141 citations

CELLULAR REQUIREMENTS FOR THE PRIMARY IN VITRO ANTIBODY RESPONSE TO DNP-FICOLL

1974 • 134 citations

The requirement for macrophages in the in vitro immune response

1971 • 134 citations

Ontogeny of the Immune Response

1964 • 133 citations

Specific Collaboration between T and B Lymphocytes across a Cell Impermeable Membrane in vitro

1972 • 132 citations

MATURATION OF THE HUMORAL IMMUNE RESPONSE IN MICE

1974 • 130 citations

LYMPHOCYTE DIFFERENTIATION FROM PRECURSOR CELLS IN VITRO*

1975 • 127 citations

Microenvironmental Aspects of Immunity

1973 • 126 citations

INDUCTION OF A HEMOLYSIN RESPONSE IN VITRO

1970 • 126 citations

The Immunological Significance of the Thymus

1963 • 126 citations

The cytoplasm in heredity

1950 • 125 citations

Embryonic Origin of the Mouse Macrophage

1972 • 124 citations

Cellular interactions in the immune response

1972 • 122 citations

Appendix of the Rabbit: A Homologue of the Bursa in the Chicken?

1963 • 120 citations

IMMUNE RESPONSES IN VITRO

1971 • 119 citations

Graft versus host reaction in tissue culture. I. Lysis of monolayers of embryo mouse cells from strains differing in the H-2 histocompatibility locus by rat lymphocytes sensitized in vitro.

1968 • 119 citations

Cellular Cooperation in the Antibody Response of Mice to Two Serum Albumins: Specific Function of Thymus Cells

1969 • 117 citations

Radioresistance of the Enhancing Effect of Cells from Carrier-Immunized Mice in an In Vitro Primary Immune Response

1971 • 117 citations

Morphological and Functional Aspects of Immunity

1971 • 116 citations

Thymic hormones and the immune response.

1974 • 116 citations

Studies on the differentiation of B lymphocytes in the mouse.

1973 • 113 citations

In vitro stimulation of mouse thymus cells by PHA and allogeneic cells

1971 • 112 citations

Regulation of lymphocyte responses in vitro,

1973 • 110 citations

Segregation of Lymphocyte Populations through Differential Migration

1969 • 108 citations

Cell-mediated immune response in vitro

1972 • 108 citations

The gut epithelium—A first level lymphoid organ?

1968 • 106 citations

The carrier effect in the secondary response to hapten-protein conjugates. V. Use of antilymphocyte serum to deplete animals of helper cells

1971 • 104 citations

The effects of anti-theta antiserum upon graft-versus-host activity of spleen and lymph node cells

1972 • 104 citations

Rocket‐Line Immunoelectroplioresis (76)

1973 • 100 citations

Initiation of Antibody Production to Sheep Erythrocytes in Vitro: Replacement of the Requirement for T-Cells with a Cell-Free Factor Isolated from Cultures of Lymphoid Cells

1972 • 99 citations

Interaction of thymus lymphocytes with histoincompatible cells. II. Recirculating lymphocytes derived from antigen-activated thymus cells

1972 • 98 citations

Studies on the ontogeny of the mouse immune system. II. Immunoglobulin-producing cells.

1968 • 98 citations

Graft reaction in tissue culture. II. Quantification of the lytic action on mouse fibroblasts by rat lymphocytes sensitized on mouse embryo monolayers.

1969 • 96 citations

Studies on the generation of B lymphocytes in the mouse embryo

1975 • 95 citations

SYNERGY AMONG LYMPHOID CELLS MEDIATING THE GRAFT-VERSUS-HOST RESPONSE

1973 • 94 citations

STIMULATION OF I<scp>G</scp>G ANTIBODY RESPONSE IN VITRO BY T CELL-REPLACING FACTOR

1973 • 93 citations

AUTOSENSITIZATION IN VITRO

1971 • 93 citations

STUDIES ON SOME PHYSICOCHEMICAL PROPERTIES OF A THYMUS HUMORAL FACTOR CONFERRING IMMUNOCOMPETENCE ON LYMPHOID CELLS

1970 • 92 citations

Cellular Traffic of the Thymus: Experiments with Chromosome Markers: Evidence from Parabiosis for an Afferent Stream of Cells

1964 • 92 citations

The Antigen System of Paramecium aurelia

1957 • 91 citations

Cell Interaction in an Immune Response in vitro: Requirement for Theta-Carrying Cells

1970 • 90 citations

Supressor Cells in the Graft vs Host Reaction

1973 • 88 citations

T and B lymphocytes

1974 • 86 citations

In Vitro Studies of Immunological Responses of Lymphoid Cells

1967 • 83 citations

INDUCTION OF ANTIBODY FORMATION AND TOLERANCE IN VITRO TO A PURIFIED PROTEIN ANTIGEN

1967 • 83 citations

Immune globulin production by the bursa of Fabricius of young chickens.

1968 • 82 citations

Studies on thymus products. 3. Epithelial origin of the serum thymic factor.

1974 • 82 citations

Allograft Response in Vitro

1972 • 81 citations

PRIMARY ANTIBODY RESPONSE IN ORGAN CULTURES

1966 • 81 citations

Antibody with homogeneous antigen binding produced by splenic foci in organ culture

1969 • 81 citations

FUNCTIONAL MATURATION OF THYMIC LYMPHOCYTE POPULATIONS IN VITRO

1972 • 80 citations

Ontogeny of mouse lymphocyte function. I. Paradoxical elevation of reactivity to allogeneic cells and phytohemagglutinin in BALB-c fetal thymocytes.

1974 • 80 citations

STUDIES ON THYMUS FUNCTION

1970 • 79 citations

Inactivation of poly-DL-alanyl bacteriophage T4 with antisera specific toward poly-DL-alanine.

1966 • 77 citations

REGULATION OF θ‐ANTIGEN EXPRESSION BY AGENTS ALTERING CYCLIC AMP LEVEL AND BY THYMIC FACTOR

1975 • 76 citations

IMMUNOCOMPETENCE OF SPLEEN CELLS FROM NEONATALLY THYMECTOMIZED MICE CONFERRED IN VITRO BY A SYNGENEIC THYMUS EXTRACT

1969 • 76 citations

Anti-θ Antibodies for detecting Thymus-dependent Lymphocytes in the Immune Response of Mice to SRBC

1970 • 76 citations

Book Review: The Lymphocyte in Immunology and Hæmopoiesis

1967 • 76 citations

Antibody Formation in Tissue Culture

1959 • 75 citations

Reconstitution of a thymus cell‐deprived immune system by syngeneic and allogeneic thymocytes in vitro

1971 • 75 citations

REDUCTION IN SURFACE CHARGE AS AN EXPLANATION OF THE RECOGNITION BY MACROPHAGES OF NUCLEI EXPELLED FROM NORMOBLASTS

1969 • 74 citations

Frequency of hapten‐specific B cells in neonatal and adult murine spleens

1974 • 73 citations

Mononuclear Phagocytes

1985 • 72 citations

The immunological properties of haptens coupled to thymus-independent carrier molecules. I. The characteristics of the immune response to dinitrophenyllysinesubstituted pneumococcal polysaccharide (SIII) and levan

1974 • 72 citations

Thymus reticulum cell cultures confer T cell properties on spleen cells from thymus‐deprived animals

1973 • 71 citations

In vitro formation of lymphocytes from embryonic thymus

1960 • 70 citations

THE PRODUCTION OF ANTIBODIES BY TISSUES LIVING OUTSIDE OF THE ORGANISM

1912 • 70 citations

IN VITRO INDUCTION OF A PRIMARY RESPONSE TO THE DINITROPHENYL DETERMINANT

1970 • 68 citations

Functional development of the interacting cells in the immune response. I. Development of T cell and B cell function.

1972 • 67 citations

The culture of lymph nodes in vitro

1952 • 67 citations

Bursa of Fabricius in Chickens: Possible Humoral Factor

1965 • 65 citations

In Vitro Studies of the Antibody Response

1961 • 64 citations

RESTRICTION OF THE CAPACITY TO RESPOND TO TWO ANTIGENS BY SINGLE PRECURSORS OF ANTIBODY-PRODUCING CELLS IN CULTURE

1969 • 64 citations

The Reticuloendothelial System and Immune Phenomena

1971 • 64 citations

In vitro Reconstitution of the Immune Response of Thymus-deprived Mice to Sheep Red Blood Cells

1970 • 64 citations

Reconstitution of the Antibody Response in Vitro of T Cell-Deprived Spleen Cells by Supernatants from Spleen Cell Cultures

1972 • 64 citations

Ontogenesis of Cell-Mediated Immunity in Murine Thymocytes and Spleen Cells and its Acceleration by Thymosin, a Thymic Hormone

1971 • 62 citations

The Skin, a First Level Lymphoid Organ?

1970 • 61 citations

Bone Marrow Macrophage Precursors. I. Some Functional Characteristics of the Early Cells of the Mouse Macrophage Series

1972 • 61 citations

Stem Cell Replacement in Normal Thymus Grafts.

1964 • 60 citations

PRIMARY ANTIBODY RESPONSE IN VITRO IN PERITONEAL CELLS

1967 • 59 citations

THE TRANSPORT OF CELLS FROM THE BURSA OF FABRICIUS TO THE SPLEEN AND THE THYMUS

1965 • 59 citations

Ontogeny of Acquired Immunity

1973 • 58 citations

Increased mitogenic reactivity of normal spleen cells to T lectins induced by thymus humoral factor (THF)

1975 • 57 citations

In vitro induction of the graft-versus-host reaction

1966 • 57 citations

Cellular Deficit in Thymectomized Mice

1970 • 57 citations

THE NATURE OF THE IMMUNOLOGIC INADEQUACY OF NEONATAL RABBITS AS REVEALED BY CELL TRANSFER STUDIES

1957 • 56 citations

The Stimulation of Splenic Foci in Vitro

1971 • 56 citations

Interactive processes in cytodifferentiation

1962 • 56 citations

IN VITRO STIMULATION OF ANTIBODY FORMATION BY PERITONEAL CELLS

1970 • 55 citations

Functional heterogeneity among the T-derived lymphocytes of the mouse

1975 • 55 citations

The mechanism of immunological unresponsiveness to picryl chloride and the possible role of antibody mediated depression.

1971 • 55 citations

STUDIES ON THYMUS FUNCTION

1970 • 54 citations

Polyanions and lipopolysaccharide acts on different subpopulations of B cells

1974 • 54 citations

COOPERATION OF LYMPHOID CELLS IN AN IN VITRO GRAFT REACTION SYSTEM

1970 • 53 citations

HUMORAL THYMIC FACTORS INFLUENCING POSTTHYMIC CELLS*

1975 • 51 citations

ADVANCES IN THE KNOWLEDGE OF THE EOSINOPHIL IN RELATION TO ANTIBODY FORMATION

1958 • 51 citations

Primary Immune Reactions in Organ Cultures

1965 • 51 citations

Peritoneal macrophages in the immune response to SRBC in vitro.

1970 • 48 citations

INDUCTION OF T‐CELL DIFFERENTIATION IN VITRO BY THYMUS EPITHELIAL CELLS*

1975 • 47 citations

Soluble mediators of t‐b interaction

1973 • 46 citations

Allograft Immunity In Vitro

1973 • 46 citations

REACTIVATION IN VITRO OF IMMUNOCOMPETENCE IN IRRADIATED MOUSE SPLEEN

1967 • 46 citations

SYNERGISM OF THYMUS AND BONE MARROW IN THE PRODUCTION OF GRAFT-VERSUS-HOST SPLENOMEGALY IN X-IRRADIATED HOSTS

1970 • 46 citations

Contemporary Topics in Immunobiology

1974 • 46 citations

The Immune Response in Mice to the Haptenic Determinant Dnp Coupled to a Thymus-Independent Carrier (Levan)

1972 • 45 citations

Methodological Approaches to the Study of Leukemias

1966 • 45 citations

Differentation of foetal mouse thymus. Ultrastructure of organ cultures and of subcapsular grafts.

1971 • 43 citations

Immune Reactivity of Lymphocytes

1976 • 43 citations

Cooperation between Carrier-reactive and Hapten-sensitive Cells in vitro

1971 • 43 citations

Induction of Theta-Positive Lymphocytes and Lymphoblasts in Mouse Bone Marrow by Mitogens

1975 • 43 citations

Participation of θ-Bearing Cell in an in vitro Assay of Transplantation Immunity

1971 • 42 citations

Restoration of Antibody Producing Capacity in Bursectomized Chickens by Bursal Grafts in Millipore(R) Chambers.

1965 • 42 citations

Ontogeny and Peripheralization of Thymic Lymphocytes

1973 • 42 citations

Reactivation of immunocompetence in spleen cells of aged mice

1974 • 41 citations

Primary-Type Antibody Response in vitro

1966 • 41 citations

ANTIGENIC AND FUNCTIONAL EVIDENCE FOR THE IN VITRO INDUCTIVE ACTIVITY OF THYMOPOIETIN (THYMIN) ON THYMOCYTE PRECURSORS*

1975 • 40 citations

INDUCTION OF ANTIBODIES IN VITRO

1969 • 40 citations

Ontogeny of mouse T-lymphocyte function

1975 • 40 citations

Antigen Binding Cells in Embryonic Chicken Bursa and Thymus

1971 • 40 citations

Immunity and the thymus

1963 • 39 citations

Thymus-derived cells as killer cells in cell-mediated immunity.

1971 • 39 citations

A Theory of Antibody Formation Involving Eosinophils and Reticuloendothelial Cells

1958 • 38 citations

Chapter 3 Specific Interactions Between Tissues During Organogenesis

1968 • 37 citations

THE FUNCTIONAL HETEROGENEITY OF MACROPHAGES AT THE SINGLE CELL LEVEL

1967 • 37 citations

Studies on the ontogeny of the mouse immune system. I. Cell-bond immunity.

1968 • 37 citations

Antigenic change and cell maturation in murine thymocytes

1970 • 37 citations

Selective effects of mitogens on subpopulations of mouse lymphoid cells

1974 • 37 citations

Generation of antibody diversity. I. Kinetics of production of different antibody specificities during the course of an immune response

1974 • 36 citations

In vitro correction of antigen-induced immune suppression: Effects of histamine, dibutyryl cyclic AMP and cholera enterotoxin

1974 • 36 citations

A bicellular mechanism in the immune response to chemically defined antigens

1971 • 36 citations

An improved system for the assay of stimulation in mouse mixed leucocyte cultures

1974 • 36 citations

An anti‐theta sensitive hapten‐carrier response in nude mice

1974 • 35 citations

Studies on the effect of a thymic humoral factor on differentiation of thymus‐derived lymphocytes

1973 • 35 citations

ONTOGENY OF MACROPHAGE RESISTANCE TO MOUSE HEPATITIS IN VIVO AND IN VITRO

1967 • 35 citations

Ontogenic development of the reactivity of macrophages to antigenic stimulation

1973 • 34 citations

THE NATURE AND MECHANISM OF STIMULATION OF IMMUNE RESPONSIVENESS BY THYMUS EXTRACTS*

1975 • 34 citations

The carrier effect in the secondary response to hapten‐protein conjugates. III. The anatomical distribution of helper cells and antibody‐forming‐cell‐precursors

1971 • 34 citations

Ontogeny of Mouse Lymphocyte Function

1974 • 34 citations

Graft-versus-host response inducedin vitro by mouse yolk sac cells

1973 • 32 citations

Thymus-antigen- and immunoglobulin-positive cells in lymph-nodes, thymus, and malignant lymphomas of NZB/NZW mice

1974 • 32 citations

The functional development of the reticulo-endothelial system. 3. The bactericidal capacity of fixed macrophages of foetal and neonatal chicks and rats.

1965 • 31 citations

Immunocompetence of embryonic hemopoietic cells after traffic to thymus.

1971 • 31 citations

Presence of Antigen-Binding Cells for Five Diverse Antigens at the Onset of Lymphoid Development: Lack of Evidence for Somatic Diversification during Ontogeny

1974 • 31 citations

Hemolysin Formation in Newborn Mice of Different Strains.

1965 • 31 citations

Transmission of radioisotopically labeled materials during embryonic induction in vitro

1963 • 31 citations

Nuclear Physics: Elements of Nuclear Physics . By F. Rasetti. New York: Prentice-Hall, Inc. $4.50.

1937 • 30 citations

Effect of Adjuvants on the Antibody Response to a Hapten on a Thymus-independent Carrier

1972 • 30 citations

Lack of requirement for cell cooperation in the antibody response to DNP conjugated to levan

1975 • 29 citations

Requirement for lymphocyte-macrophage interaction in the response of mouse spleen cultures to pneumococcal polysaccharide

1971 • 28 citations

Allogeneic Interactions Provide Evidence for a Novel Class of Immunological Reactivity

1972 • 28 citations

STUDIES ON CHARACTERIZATION OF THE LYMPHOID TARGET CELL FOR ACTIVITY OF A THYMUS HUMORAL FACTOR

1973 • 28 citations

Comparison of the suppressive effect of thymus cells and the suppression by neonatal application of antigen

1973 • 28 citations

Functional development of the interacting cells in the immune response. II. Development of immunocompetence to heterologous erythrocytes in vitro.

1972 • 27 citations

Developmental studies of mouse thymus and spleen.

1963 • 27 citations

Reconstitution of immunocompetence in B cells by addition of concanavalin A or concanavalin A-treated thymus cells.

1973 • 27 citations

Nonspecific stimulation of antibody production in surgically bursectomized chickens by bursa-containing diffusion chambers.

1968 • 27 citations

IN VITRO STIMULATION OF ANTIBODY FORMATION BY PERITONEAL CELLS

1970 • 27 citations

Antibody Diversity: Is it All Coded for by the Germ Line 206

1973 • 27 citations

Antigenic differences between spleen‐seeking and lymph node‐seeking thymus cells

1973 • 26 citations

INDUCTION OF A HEMOLYSIN RESPONSE IN VITRO

1971 • 26 citations

Thymosin and Other Thymic Hormones: Their Nature and Roles in the Thymic Dependency of Immunological Phenomena

1973 • 26 citations

Ontogeny of the antibody‐forming cell line in mice. I. Kinetics of appearance of mature B cells

1975 • 26 citations

MOUSE FETAL LIVER AND THYMUS: POTENTIAL SOURCES OF IMMUNOLOGICALLY ACTIVE CELLS*

1963 • 26 citations

COOPERATION OF LYMPHOID CELLS IN AN IN VITRO GRAFT REACTION SYSTEM

1971 • 25 citations

IMMUNOSUPPRESSION BY EMBRYONIC LIVER CELLS

1975 • 25 citations

Studies on the Ontogeny of the Mouse Immune System

1968 • 24 citations

IN VITRO STUDIES ON RADIATION LYMPHOID RECOVERY OF MOUSE SPLEEN

1966 • 24 citations

Splenic determination of immunocompetence: Influence on other lymphoid organs

1971 • 24 citations

In vitro synthesis of gamma M-like globulin by various chick embryonic cells.

1966 • 24 citations

Macrophage Functional Heterogeneity in the in vitro Induced Immune Response

1971 • 24 citations

DNA replication as a prerequisite for the induction of primary antibody response

1972 • 23 citations

Ontogeny of the antibody-forming cell line in mice. II. Maturation of B cells during fetal development.

1976 • 23 citations

Antibody Diversity: A Case for its Generation after Antigenic Stimulation

1974 • 22 citations

Cellular composition of the chicken thymus; effects of neonatal bursectomy and hydrocortisone treatment

1973 • 22 citations

T &amp; B lymphocytes in thymus of SJL/J mice

1975 • 22 citations

ONTOGENY OF THYMUS CELL FUNCTION*

1975 • 22 citations

A bicellular mechanism in the immune response to chemically defined antigens

1971 • 22 citations

Production of Functional T Cells after Treatment of Bone Marrow with Thymic Factor

1973 • 21 citations

A three-cell mosaic culture: In vitro immune response by a combination of pure B- and T-cells with peritoneal macrophages

1972 • 21 citations

Role of the Thymus in the Development of Immunocompetence of Embryonic Liver Cells in Vitro

1968 • 21 citations

Methodological Approaches to the Study of Leukemias

1966 • 21 citations

Antigens and Antibodies as Cell Phenotypes

1959 • 21 citations

Antibody Formation Studied at the Single-Cell Level

2015 • 19 citations

THYMUS-INFLUENCED IMMUNOLOGICAL MATURATION OF EMBRYONIC LIVER CELLS1,2

1971 • 19 citations

OLIGOMERIC IGA: THE MAJOR COMPONENT OF THE IN VITRO PRIMARY RESPONSE OF MOUSE SPLEEN FRAGMENTS

1973 • 19 citations

MATURATION OF HEMOLYSIN-PRODUCING CELL CLONES

1969 • 19 citations

Relation of the Thymus to the Formation of Immunologically Reactive Cells

1967 • 18 citations

Lymphoid cell dependence of eosinophil response to antigen. 3. Comparison of the rate of appearance of two types of memory cells in various lymphoid tissues at different times after priming.

1973 • 18 citations

Normal development of the thymus‐dependent limb of humoral immune responses in mice

1973 • 18 citations

Antibody Diversity: Is It All Coded for by the Germ Line Genes?

1974 • 17 citations

The cloning of macrophages in agar: Identification of the cells by electron microscopy

1966 • 17 citations

Cell interactions in antibody formation in vitro. II. the interaction of the third cell and antigen.

1972 • 17 citations

Comparison of the immune response potential of newborn mice to T-dependent and T-independent synthetic polypeptides.

1976 • 16 citations

Studies on the Source and Action of the T-Cell Replacing Factor (TRF)

1973 • 16 citations

Immunogenic function of macrophages: In vitro production of antibodies to a hapten-carrier conjugate

1972 • 16 citations

Mechanisms in immune tolerance

1974 • 15 citations

Thymus–Marrow Cell Interaction evaluated by PHA Stimulation and Graft versus Host Activity

1971 • 15 citations

Effect of Adult Peritoneal Cells on the Antibody Response of Newborn Mice to Sheep Red Blood Cells

1971 • 15 citations

In vitro primary immune response resulting from the interaction between bone marrow-derived and thymus cells

1970 • 15 citations

Fetal Lymphoid Tissues: Antibody Production in Vitro

1973 • 15 citations

?? ANTIGEN ON MOUSE LYMPHOCYTES STIMULATED WITH PHYTOHAEMAGGLUTININ

1971 • 15 citations

Lymphoid Cell Migration

1971 • 15 citations

On the function of the embryonic thymus.

1964 • 14 citations

THE CELLULAR BASIS OF IMMUNOLOGICAL TOLERANCE IN NEWBORN ANIMALS

1966 • 14 citations

Analysis of Lymphoid Cell Types Developing in Mouse Foetal Liver

1974 • 14 citations

Initiation of primary-type and secondary-type antibody responses to bacteriophage phiX 174 in vitro.

1968 • 13 citations

FACTORS INFLUENCING ACTIVATION OF B‐CELLS IN IMMUNITY*

1975 • 13 citations

IDENTIFICATION OF θ‐BEARING T‐CELLS DERIVED FROM BONE MARROW CELLS TREATED WITH THYMIC FACTOR*

1975 • 12 citations

Lymphoid Cell Dependence of Eosinophil Response to Antigen

1973 • 12 citations

Anti-TNP antibody responses in vitro: augmented primary responses of carrier-primed spleen cells.

1971 • 12 citations

Cell Interactions in Antibody Formation in Vitro

1972 • 12 citations

In vitro studies on thymus and lung differentiation following urethan treatment.

1965 • 11 citations

Peritoneal macrophage response in neonatal mice.

1973 • 11 citations

Role of Macrophages in the Development of Immunological Maturity in Rat

1970 • 11 citations

Further evidence concerning macrophages producing 19 S-antibody in mice

1969 • 11 citations

Ultrastructural differences between macrophages of newborn and adult mice.

1976 • 11 citations

Thymic Humoral Factors

1973 • 11 citations

Suppression by Soluble Factor Released from B Cells

1976 • 11 citations

GRAFT-VS.-HOST REACTION IN TISSUE CULTURE

1973 • 11 citations

FUNCTIONAL MATURATION OF LYMPHOCYTES WITHIN EMBRYONIC MOUSE THYMUS

1971 • 10 citations

Primary Antibody Response Induced in vitro Among Cells from Normal Animals

1967 • 10 citations

Short pulses of antigen induce in vitro an antibody response to haptenic determinants

1974 • 10 citations

Growth and differentiation of cells of lymphoid origin on embryo cell monolayers.

1965 • 10 citations

Antibody formation in newborn mice initiated through adult macrophages. Abstr.

1967 • 10 citations

Initiation of Primary-Type and Secondary-Type Antibody Responses to Bacteriophage φX 174 in Vitro

1968 • 9 citations

The enhancement of a primary in vitro anti‐hapten response by carrier priming

1972 • 9 citations

SPECIFIC INHIBITION OF THE GRAFT-VERSUS-HOST REACTION IN FETAL OR NEONATAL LIVER CHIMERAS

1975 • 8 citations

MATURATION OF HEMOLYSIN-PRODUCING CELL CLONES

1970 • 8 citations

Development of B lymphocytes

1975 • 8 citations

The Development of Immunocompetent Cells

1968 • 7 citations

ACTIVATION OF IMMUNE COMPETENCE BY THYMUS FACTORS*

1975 • 7 citations

Communications

1971 • 7 citations

Concluding Remarks to Session Eight: Suppressor Cells and Enhancing Antibodies: Immune Agents of the Facilitation Reaction

1976 • 6 citations

Antibody response to bacteriophage ϕX 174 in vitro: Demonstration of immunological memory in terms of IgM and IgG responses

1972 • 6 citations

Graft versus host inhibition. I. Incubated parental strain spleen and liver cells administered to F1 mice.

1969 • 6 citations

Early evaluation of mixed leukocyte interactions in mice and guinea pigs using measurements of protein synthesis

1973 • 6 citations

The Role of Soluble Factors in T-B Cell Collaboration

1973 • 6 citations

Requirements for Development of Immunocompetence of Embryonic Liver Cells: the Graft-versus-Host Response

1973 • 6 citations

Differentiation of the thymus-leukemia (TL) antigen in the thymus of mouse embryos.

1968 • 6 citations

Thymus Extracts Induce Differentiation of Thymus Derived Cells

1973 • 6 citations

Transient Appearance of PHA-Reactive Thymocytes in the Foetal Mouse

1973 • 5 citations

Immunological Potential of Yolk Sac Cells

1976 • 5 citations

Chapter 1 Reception of Immunogenic Signals By Lymphocytes

1974 • 5 citations

Kinetics of proliferation of splenic macrophage precursor cells during the early primary immune response.

1972 • 5 citations

Thymus cell traffic induced by antigen stimulation

1974 • 4 citations

Evidence of macrophages being 19 S-antibody producing cells, as shown by a modification of the Plaque—Technique

1969 • 4 citations

Studies on the Maturation of Immune Responsiveness in the Mouse

1973 • 4 citations

The Lymphoid Development of the Embryonic Chicken Thymus in Organ Culture

1973 • 4 citations

Dissociated thymus and bone marrow cells: Synergism in Graft Versus Host reaction

1973 • 4 citations

THE ABSOLUTE REQUIREMENT FOR T‐CELLS IN THE INDUCTION OF IGM‐SECRETING CELLS, IN VITRO

1975 • 4 citations

TRANSPLANTATION OF ADULT PERITONEAL CELLS INTO NEWBORN MICE

1969 • 4 citations

A Comparison of the Immunologic Function of Thymus Cells at Varying Stages of Maturation

1970 • 4 citations

Immunosuppression by Fetal Liver as a Model for Tolerance to Self

1976 • 3 citations

Analysis of the role of different cell types in the genetic regulation of antibody production to the thymus‐independent synthetic polypeptide poly (<scp>D</scp>Tyr, <scp>D</scp>Glu)‐poly(<scp>D</scp>Pro)‐‐poly (<scp>D</scp>Lys)

1975 • 3 citations

Regulatory Cells in the Bone Marrow

1976 • 3 citations

The thymus origin of the carrier‐specific cell in an anti‐hapten response in vitro

1972 • 3 citations

Oligocellular mechanism in the production of antibodies: in vitro response to a haptenic determinant

1973 • 3 citations

Cell Interactions in the In Vitro Production of Antibodies to Chemically Defined Antigens

1971 • 3 citations

Involvement of Cells With ‘B’ Properties in Development of T Helpers

1976 • 3 citations

Proceedings: Immunosuppression by embryonic liver cells: a model for establishment of tolerance to self.

1975 • 1 citations

Differential Responses of Macrophage Precursors and Antibody Forming Cells to Immunization

1971 • 1 citations

Microenvironmental Aspects of Lymphatic Tissue: Summary

1973 • 1 citations